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Found 827 clinical trials
Prospective European Multicenter Study on Aortic Valve Replacement: (E-AVR Registry)

Traditional and transcatheter surgical treatments of severe aortic valve stenosis (SAVS) are increasing in parallel with the improved life-expectancy. Recent randomized trials (RCTs) reported comparable or non-inferior mortality with transcatheter treatments compared to traditional surgery. However, RCTs have the limitation of being a mirror of the predefined inclusion/exclusion criteria, without …

aortic valve stenosis
coronary artery disease
aortic valve replacement
stenosis
regurgitation
  • 6 views
  • 25 Jan, 2021
  • 2 locations
Japanese Upper GI Symptoms Compared With Iranian and Canadian Patients Presenting

The purpose of this prospective cohort study is to compare upper GI symptoms and endoscopy findings in Canada with Japan and Iran, and correlate this with the upper GI microbiome. The investigators plan to recruit 500 new patients referred for upper GI endoscopy in Canada (McMaster University) and 500 in …

endoscopy
gastroesophageal reflux
reflux
16s rrna
esophagogastroduodenoscopy
  • 111 views
  • 15 Feb, 2022
  • 1 location
Pakistan Study of Premature Coronary Atherosclerosis in Young Adults

Coronary heart disease (CHD) is a major cause of morbidity, disability, mortality, and health expenditures worldwide. A wealth of studies has demonstrated that people of South Asian ancestry have a higher risk of CHD and particularly premature CHD than most other racial/ethnic groups, and recent research suggests that this risk …

Accepts healthy volunteers
atherosclerosis
cardiovascular disease
angiography
  • 0 views
  • 21 Dec, 2021
  • 1 location
Psoriasis Longitudinal Assessment and Registry (PSOLAR)

The purpose of this study is to further evaluate the safety of infliximab, ustekinumab, and guselkumab in patients with plaque and other forms of psoriasis. The study also includes patients receiving other therapies, such as non-biologic and other biologic agents. The registry also evaluates patient and disease characteristics, including patient-reported …

psoriasis
ustekinumab
brodalumab
biological drug
interleukin-17
  • 4563 views
  • 06 Jun, 2022
  • 81 locations
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford (CoRDS)

CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, international patient registry for all rare diseases. This program allows patients and researchers to connect as easily as possible to help advance treatments and cures …

other disease
rare diseases
  • 4 views
  • 15 Jul, 2022
  • 2 locations
A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

This study is an access and distribution protocol for unlicensed cryopreserved cord blood units (CBUs) in pediatric and adult patients with hematologic malignancies and other indications.

cancer
hematologic malignancy
  • 643 views
  • 11 Aug, 2022
  • 127 locations
Glucose Variability and Cognition in Prediabetes

This study examines the association of variability in glucose values over a 10-day period with cognitive function and functional status among individuals with prediabetes, aged 50 or older.

Accepts healthy volunteers
continuous glucose monitoring
  • 0 views
  • 20 Apr, 2022
Prevention of Human Papillomavirus (HPV) Infection in Paediatric Kidney and Liver Transplant Recipients and in Paediatric Patients With Advanced Chronic Kidney Disease

Due to their immunosuppressive therapy, solid-organ transplant (SOT) recipients bear a 10 to 100 times higher risk of human papillomavirus (HPV)-associated malignancies than healthy individuals

cancer
immunosuppressive agents
nephropathy
  • 3 views
  • 25 Feb, 2022
  • 1 location
Telerehabilitation for TMD

quality-of-life outcomes in each group will determine (based on a 10% margin) whether delivering physical therapy via telerehabilitation is as good as standard in-person care for these individuals. Long

  • 0 views
  • 10 Jul, 2022
  • 1 location
Impact of a Task Delegation to ICU Nurses for Midlines' Placement (IDEM)

catheter is a 10 to 20 cm long peripheral venous catheter, which can be used for up to 28 days. These features make it a good alternative to central venous and conventional peripheral venous catheters.

thrombosis
  • 0 views
  • 09 Aug, 2022
  • 1 location