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Found 598 clinical trials
Imaging and Biopsy of HIV-Infected Individuals Undergoing Analytic Treatment Interruption

assigned to 1 of 2 groups: One group will stay on ART. They will have 2 study visits: the first 45 days after screening, and the second 12 to 16 weeks later. They will have a PET/CT scan at each

  • 25 Oct, 2022
  • 1 location
Accurate Dosimetry and Biomarkers Improve Survival in HCC Patients Treated With Resin 90 Yttrium (90Y)-Microspheres (DOSEY90)

, biomarkers assessed from blood samples prior and after the treatment and voxel-based dosimetry obtained from post-treatment PET/CT images acquisitions.

  • 23 Mar, 2022
  • 1 location
A Molecular Imaging-Derived Biomarker of PSMA Expression - Revealing Theranostic Potential in Gastrointestinal Tumors (Focusing on Hepatocellular Carcinoma) (GIPSMA)

determine if i) biopsy-derived tissue of newly diagnosed patients exhibit a PSMA expression profile, ii) PSMA-PET/CT shows upregulated PSMA expression in-vivo, iii) such a molecular imaging approach

  • 13 Oct, 2022
  • 1 location
Effect of Thyrotropin Level on Iodine Uptake in Metastatic Differentiated Thyroid Cancer

effect of thyrotropin on iodine uptake in metastatic DTC during levothyroxine withdrawal by two times 124I PET/CT scans on different endogenous thyrotropin levels.

  • 16 May, 2021
  • 2 locations
Long-Term Transcutaneous Stimulation and Essential Tremor: A PET Study

seeking to perform three standard PET/CT sessions on a subset of these subjects (n=10) at Mayo Clinic - Rochester to evaluate changes in brain metabolic activity as a result of 3 months treatment with the

movement disorder
hand tremor
brain stimulation
  • 17 Mar, 2022
  • 1 location
Free-Base Nicotine or Nicotine Salt e-Liquids in Current E-Cigarette Smokers, PeloPET Study

This clinical trial studies the effect of free-base compared with nicotine salt based e-liquids on electronic cigarette (EC) puffing behavior, abuse liability, and deposition and absorption of nicotine in the respiratory tract and rate of uptake in the brain in current EC smokers. The results from this study may provide …

  • 04 Oct, 2022
  • 1 location
[177Lu]Ludotadipep Treatment in Patients With Metastatic Castration-resistant Prostate Cancer.

The study aims to evaluate the stability and efficacy after administration of [177Lu]Ludotadipep in patients with metastatic castration resistant prostate cancer (mCRPC), with dose-escalation applied to determine the appropriate dose.

  • 15 Aug, 2021
Per-operating Use of a Probe for Detection of β+

The objective of the study is to evaluate the sensibility of the probe Forimtech to detect β+ emission in vivo in humans and its usefulness during elective surgical procedure Hypothesis:The probe Forimtech is able to allow per-surgery detection of tumoral lesions sensible to 18F-FDG and to help in the realization …

pet/ct scan
  • 29 Jun, 2022
  • 1 location
Salvage Systemic Therapy With or Without Stereotactic Ablative Radiotherapy for Recurrent Ovarian Cancer (SABR-ROC)

Rationale Ovarian cancer is the 3rd most common gynecologic malignancy in Korea. The standard treatment is tumor debulking surgery with or without adjuvant chemotherapy. However, with a recurrence rate of 80%, the treatment results are the worst among gynecological cancers. The use of target and immune agents have demonstrated to …

  • 04 Oct, 2022
  • 1 location
Reinducing Radioiodine-sensitivity in Radioiodine-refractory DTC Using Lenvatinib (RESET) (RESET)

This is a single-centre open label phase II study evaluating the effect of lenvatinib treatment for restoring radioiodine uptake and retention in radioiodine-refractory (RAI-R) thyroid cancer to warrant I-131 therapy.

  • 24 Apr, 2022
  • 1 location