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Found 32 clinical trials
HIV And Parasitic Infection (HAPI) Study (HAPI)

highly sensitive multi-parallel stool PCR test. Hypothesis: highly sensitive stool PCR testing will demonstrate that disease burden of parasitic infection in PLWH in Malawi is higher than historically

Accepts healthy volunteers
  • 0 views
  • 26 May, 2022
  • 1 location
Effectiveness of COVID-19 Vaccine in Hematopoietic Stem Cell Transplant Patients (ESCVHSCT)

COVID-19 vaccinations are predicted to be a huge success in pandemic control. However, the majority of the studies were conducted on healthy individuals, and the efficiency of COVID-19 vaccination in post-transplant patients is uncertain. In the setting of HSCT, the extreme immunosuppression caused by the conditioning regimen and the graft …

  • 0 views
  • 28 May, 2022
  • 1 location
Early Targeted Antibiotic Therapy in Patients With Sepsis.

The aim of this study is to assess the efficacy of early targeted antibiotic therapy in patients with sepsis and septic shock using the new biomarker Sirtuin 1 and PCR for bacterial resistance detection. The primary outcome is change in SOFA score (ΔSOFA) which will be calculated by subtracting the …

antibiotics
septic shock
antibiotic therapy
shock
  • 0 views
  • 25 Jul, 2022
  • 1 location
A Clinical Trial for Chlorhexidine as Treatment for Vulvovaginal Candidiasis

The overall aim of this study is to investigate if vaginally applied 1% chlorhexidine gluconate (CHG) could be an alternative treatment to oral fluconazole (FLZ), both during an acute episode and as prophylaxis, against recurrent infections of vulvovaginal candidiasis (RVVC). RVVC is very common in fertile women. Up to six …

  • 0 views
  • 02 Jun, 2022
  • 1 location
Phase I Randomized Double-Blind Clinical Trial With New SARS-CoV-2 CoVacHGMix Type 5 Adenoviral Vector Vaccine in Healthy Volunteers Aged 18-45 Years

The CoVacHGMix adenoviral vector vaccine is a new vaccine developed to protect against SARS-CoV-2 and is a Phase I study designed based on adaptive clinical trial standards. In this Phase I study, it is aimed to test the safety and efficacy of the investigational product at 2 different dose levels …

Accepts healthy volunteers
  • 0 views
  • 20 Sep, 2022
  • 1 location
A Real-world Evidence Study of BNT162b2 mRNA Covid-19 Vaccine in Brazil

. Participants with a positive polymerase chain reaction (PCR) test for SARS-CoV-2 will be classified as cases, and those with negative PCR test for SARS-CoV-2 will be classified as controls. Cases will be

  • 0 views
  • 21 Mar, 2022
  • 1 location
Patient Reported Health-Related Quality of Life Associated With COVID-19.

COVID-19 pandemic elicited broad medical, economic, and social consequences. There is limited research and outstanding data gaps related to understanding the impact of long-term effect of COVID-19 on Health-Related Quality of Life (HRQoL) and Work Productivity and Activity Impairment (WPAI) in the outpatient settings in the US. Information on the …

  • 0 views
  • 10 Mar, 2022
  • 1 location
Comparative Study of Patterns of Immune Response to COVID 19 Vaccination

An effective vaccine stands as the most effective way for controlling the COVID 19 pandemic , yet, immunogenic vaccine efficacy needs to be extensively studied . T cell responses against the structural proteins have been found to be the most immunogenic in peripheral blood mononuclear cells of convalescent SARS-CoV1 patients …

  • 0 views
  • 17 Jun, 2022
  • 1 location
Large-scale COVID-19 Population Screening

Infectious diseases pose a threat to the life of individuals worldwide. The pandemic has highlighted the need to develop an innovative and cost- effective large population-based screening methodology. The investigators propose a two-fold improvement barcode-labeled testing strategy specifically for pooled samples. This platform combines isothermal amplification and real-time electrochemical detection; …

  • 0 views
  • 03 Sep, 2021
  • 3 locations
KIDney Injury in Times of COVID-19 (KIDCOV) (KIDCOV)

from 3 different states, California, Michigan, and Illinois. Study endpoints will be assayed from urine samples mailed to the study team at 2, 6, and 12 months after their date of PCR test, with no

Accepts healthy volunteers
renal injury
  • 0 views
  • 11 May, 2022
  • 3 locations