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Found 114 clinical trials
Hyperandrogenemia and Altered Day-night LH Pulse Patterns (CRM008)

The purpose of this study is to determine if, in mid- to late pubertal girls with hyperandrogenism, androgen-receptor blockade (spironolactone) improves the ability of progesterone to acutely reduce waking luteinizing hormone pulse frequency (primary endpoint).

testosterone level
progesterone
androgens
testosterone
hirsutism
  • 68 views
  • 29 May, 2022
  • 1 location
Does Spironolactone Normalize Sleep-wake Luteinizing Hormone Pulse Frequency in Pubertal Girls With Hyperandrogenism?

The purpose of this study is to determine if, in mid- to late pubertal girls with hyperandrogenism (HA), androgen-receptor blockade (spironolactone) alone normalizes sleep-wake luteinizing hormone (LH) pulse frequency (primary endpoint) and overall LH and follicle-stimulating hormone secretion (secondary endpoints).

  • 8 views
  • 04 Oct, 2022
  • 1 location
Research on Risk Factors and Comprehensive Intervention Measures of Polycystic Ovary Syndrome Complicated With Mental Diseases Such as Depression and Anxiety (PCOS)

The current study intends to establish a prediction method and evaluation system for polycystic ovary syndrome (PCOS) complicated with affective disorder, such as depression and anxiety, through

  • 8 views
  • 27 Oct, 2022
  • 1 location
Administration of Kisspeptin to Subjects With Reproductive Disorders

The investigators are seeking participants for a study of the role of kisspeptin in the reproductive system. Kisspeptin is a naturally occuring hormone in humans that stimulates the production of reproductive hormones. The investigators hypothesize that kisspeptin administration will be a useful tool for characterizing certain reproductive disorders.

secondary hypogonadism
acne
prolactin
klinefelter syndrome
estradiol
  • 808 views
  • 04 Oct, 2022
  • 1 location
Behavioral Economics for Activity Motivation in Adolescents and Young Adults With Prediabetes and Type 2 Diabetes

There is an urgent need to engineer targeted physical activity interventions that are effective and scalable for obese adolescents and young adults (AYA) with type 2 diabetes (T2D), who often have very low levels of physical activity. The BEAM Trial is a proposed mobile health (mHealth) intervention that uses behavioral …

diabetes
  • 0 views
  • 24 Oct, 2022
  • 1 location
Ultrasound Characterization of Ovarian Follicle Dynamics During Weight Loss

menstrual cycles versus obese women with irregular menstrual cycles and/or polycystic ovary syndrome (PCOS).

multivitamins
polycystic ovary syndrome
insulin
hormonal contraception
diabetes
  • 284 views
  • 16 Oct, 2022
  • 1 location
The Physiological Responses and Adaptation of Brown Adipose Tissue to Chronic Treatment With Beta3-Adrenergic Receptor Agonists

Background Brown adipose tissue (BAT) is a type of fat in the body. It may prevent weight gain, improve insulin sensitivity, and reduce fatty liver. Researchers want to see if BAT helps the body burn energy. Objective To learn more about how BAT works to burn energy. Eligibility Healthy people …

insulin
vitamins
insulin sensitivity
insulin resistance
body mass index
  • 340 views
  • 24 Oct, 2022
  • 1 location
Go Girls! Fitness Support Group Intervention Effectiveness Study (CBS002)

The main purpose of this study is to determine if the Go Girls! program to take place at the Kluge Children's Rehabilitation Center Therapeutic Recreation Gymnasium, intended to introduce girls to a fun, non-threatening environment of exercise with peer support, improves scores on a physical activity enjoyment scale (PACES). Information …

insulin
diabetes
type 2 diabetes mellitus
insulin resistance
  • 85 views
  • 04 Oct, 2022
  • 1 location
Hysteroscopic Findings in Ovarian Polycystic and Unexplained Infertile Women.

In many PCO infertile patients, abnormal endometrial echogenicity and thickness are documented by TVS and proved by endometrial biopsy in some cases. Should patients with normal appearance of

hysteroscopy
cavities
prolactin
follicle stimulating hormone
  • 22 views
  • 14 Oct, 2021
  • 1 location
Saroglitazar Magnesium 4 mg in the Treatment of NAFLD in Women With PCOS (EVIDENCES VII)

This is a multicenter, phase 2A, randomized, double-blind, placebo-controlled study designed to evaluate the efficacy and safety of Saroglitazar Magnesium in women with well characterized PCOS

  • 1108 views
  • 11 May, 2022
  • 9 locations