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Found 114 clinical trials
Study to Assess Potential Impairments in Estradiol Augmentation of Gonadotropin Secretion in Polycystic Ovary Syndrome (CRM009)

endpoint) is reduced in adult women with polycystic ovary syndrome.

hirsutism
testosterone
Accepts healthy volunteers
luteinizing hormone
hyperandrogenism
  • 251 views
  • 26 May, 2022
  • 1 location
A Clinical Trial to Evaluate the Efficacy, Tolerability, and Safety of a Fixed Dose Combination of Spironolactone, Pioglitazone & Metformin (SPIOMET) in Polycystic Ovary Syndrome (PCOS) (SPIOMET4HEALTH)

combination of Spironolactone, Pioglitazone and Metformin (SPIOMET) for adolescent girls and young adult women with polycystic ovary syndrome. Study description: Currently, there is no European

hirsutism
insulin
testosterone
hyperandrogenism
pioglitazone
  • 79 views
  • 04 Oct, 2022
  • 3 locations
Myo-Inositol for Infertility in PCOS

This will be a prospective, double-blind randomized clinical trial of letrozole and placebo versus letrozole and inositols for up to 5 treatment cycles of ovulation induction or until pregnancy is achieved. All participants and members of the research team will be blinded to the treatment arms. Placebo and inositol supplement …

letrozole
infertility
ovulation induction
inositol
hyperandrogenism
  • 57 views
  • 30 May, 2022
  • 1 location
MYPP-trial: Myo-inositol Supplementation to Prevent Pregnancy Complications in Women With Polycystic Ovary Syndrome. (MYPP)

Polycystic Ovary Syndrome (PCOS) is the most common endocrine disorder in women of reproductive age. PCOS is a heterogeneous condition, characterised by metabolic disturbances, insulin

insulin
insulin resistance
testosterone
inositol
prenatal
  • 0 views
  • 07 Oct, 2022
  • 1 location
A Study of Safety and Efficacy of Tildacerfont in Females With Polycystic Ovary Syndrome and Elevated Adrenal Androgens

An investigation of the safety and efficacy of tildacerfont in women with PCOS and elevated adrenal androgens

androgens
body mass index
  • 26 views
  • 04 Oct, 2022
  • 7 locations
Continuous Versus Cyclical OCP Use in PCOS (CCOUP)

The mainstay treatment for females with Polycystic Ovary Syndrome (PCOS) has long been a combination of an oral contraceptive pill or OCP (containing both estrogen and progestin) along with an

hirsutism
androgens
testosterone
spironolactone
Accepts healthy volunteers
  • 467 views
  • 04 Oct, 2022
  • 1 location
Letrozole Versus Laparoscopic Ovarian Drilling in Polycystic Ovary Syndrome

Polycystic ovary syndrome is the major cause of anovulatory infertility. Clomiphene citrate is the most commonly used oral agent for ovulation induction in this group, but there are some

letrozole
body mass index
clomiphene
ovulation induction
semen analysis
  • 200 views
  • 30 May, 2022
  • 1 location
Treating PCOS With Semaglutide vs Active Lifestyle Intervention

Girls with obesity and polycystic ovarian syndrome will receive either glucagon like peptide-1 receptor agonist therapy or a dietary intervention for 12 weeks to decrease the metabolic syndrome

insulin
receptor agonist therapy
dietary modification
insulin sensitivity
semaglutide
  • 239 views
  • 04 Oct, 2022
  • 1 location
Relative Desirability of Metformin vs. Birth Control Pill in Treating PCOS in Women of Later Reproductive Age (SHK002)

The goal of this study is to determine the relative desirability of metformin vs. oral combined hormonal contraceptives (OCs) in treating Polycystic Ovary Syndrome (PCOS) in women of later

insulin
type 2 diabetes mellitus
Accepts healthy volunteers
oligomenorrhea
hyperandrogenism
  • 197 views
  • 15 Feb, 2022
  • 1 location
Feasibility Study of the AblaCare System in Transvaginal Ablation of Ovarian Tissue Under ULTRAsound Visualization in Women With Infertility Due to Polycystic Ovary Syndrome (ULTRA-US)

women with infertility due to polycystic ovary syndrome (PCOS) who have not responded to first-line ovulation induction treatment or are contraindicated for or decline such treatment.

hirsutism
androgens
testosterone
oligomenorrhea
antral
  • 0 views
  • 04 Oct, 2022
  • 1 location