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Found 37 clinical trials
  • 1 views
  • 07 Nov, 2020
  • 2 locations
Study to Assess Safety Tolerability and Efficacy of Afabicin in The Treatment of Participants With Bone or Joint Infection Due to Staphylococcus

-susceptible S. aureus (MSSA) and methicillin-resistant S. aureus (MRSA)] and/or coagulase-negative staphylococci (CoNS) and to compare it to standard of care (SOC).

  • 7 views
  • 01 Aug, 2021
  • 17 locations
A Trial to Evaluate the Loading Dose Required to Achieve Therapeutic Serum Teicoplanin Concentration Timely

treatment of methicillin-resistant Staphyllococcus aureus (MRSA) bacteremia.

methicillin
bacteremia
blood culture
vancomycin
MRSA
  • 1 views
  • 07 Nov, 2020
Antimicrobial Prophylaxis for Skin Colonization With Propionibacterium Acnes in Primary Open Shoulder Surgery

INESS Antibiotic Prophylaxis in Orthopedic Guide recommends the use of Cefazolin at induction for all orthopaedic procedure with implantation of internal fixation device. With the increasing rate of identified P. acnes shoulder surgery infection despite the use of recommended skin preparation and preoperative prophylactic antibiotics, a question arises; Is Cefazolin …

  • 142 views
  • 20 Jul, 2021
  • 2 locations
Study to Evaluate Safety and Activity of TRL1068 in Prosthetic Joint Infections

TRL1068 is expected to eliminate the pathogen-protecting biofilm in the prosthetic joint and surrounding tissue, thus making these pathogens substantially more susceptible to established antibiotic treatment regimens. This initial study is designed to assess overall safety and pharmacokinetics (PK) of TRL1068. The overall goal of the development program is to …

  • 0 views
  • 09 Jul, 2021
  • 2 locations
Community-Acquired Methicillin Resistant Staphylococcus Aureus Colonization in Pregnant Women and Infections in Newborns

Background: Community acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) is an emerging pathogen of the 21st century whose incidence as a cause of local and invasive

methicillin
staphylococcus
MRSA
decolonization
  • 0 views
  • 07 Nov, 2020
  • 1 location
Dalbavancin for the Treatment of Acute Bacterial Skin and Skin Structure Infections in Children Known or Suspected to be Caused by Susceptible Gram-positive Organisms Including MRSA

To determine the safety and descriptive efficacy of dalbavancin for the treatment of acute bacterial skin and skin structure infections in children, aged birth to 17 years (inclusive), known or suspected to be caused by susceptible Gram-positive organisms, including methicillin-resistant strains of Staphylococcus aureus.

impetigo
induration
staphylococcus
systemic infection
platelet count
  • 0 views
  • 24 Jan, 2021
  • 96 locations
Antibiotic Prophylaxis in High-Risk Arthroplasty Patients

To determine the effectiveness of a 7-day course of an oral, prophylactic antibiotic on the incidence of periprosthetic joint infection and wound complications following primary total hip and knee arthroplasty in a high-risk patient population.

  • 0 views
  • 13 May, 2021
  • 2 locations
Selective Decontamination of the Digestive Tract in Intensive Care Unit Patients

the frequency of infections with resistant bacteria such as multi-resistant Gram negative organisms, MRSA and Clostridium difficile. SuDDICU is a cross-over, cluster randomised trial comparing

nosocomial infections
antibiotics
mechanical ventilation
antibiotic therapy
critical illness
  • 13 views
  • 28 Jan, 2021
  • 3 locations
Study to Optimize the Use of New Antibiotics

carbapenem-resistant Acinetobacter baumannii and Pseudomonas aeruginosa, carbapenem-resistant enterobacteria, vancomycin-resistant Enterococcus faecium and methicillin-resistant Staphylococcus aureus

bacteremia
carbapenem
antibiotic therapy
staphylococcus
ceftazidime-avibactam
  • 3 views
  • 24 Jan, 2021
  • 20 locations