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Found 332 clinical trials
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A Pivotal, Multicenter, Blinded, Sham Procedure-Controlled Trial of Renal Denervation by the Peregrine System™ Kit, in Subjects With Hypertension

The TARGET BP I Trial is a randomized, blinded, multi-center, international, sham-procedure controlled trial, comparing renal denervation performed with the Peregrine System Kit in the treatment

  • 67 views
  • 10 Aug, 2020
  • 1 location
featured
Comparative evaluation of the performance and safety of A-CP HA Kit, for the preparation of a combination of platelet-rich plasma and hyaluronic acid, versus hyaluronic acid alone and placebo in patients with knee osteoarthritis

The purpose of this study is to assess the performance and safety of a combination of hyaluronic (HA) and platelet-rich plasma (PRP) in knee injection treatment for use in relieving symptoms in patietns with knee pain. To qualify you must be between ages 50 and 80, have Grade 2 or …

hyaluronic acid
knee pain
  • 109 views
  • 11 Jun, 2020
  • 1 location
featured
A Randomized Phase 3 Study of Sitravatinib in Combination with Nivolumab Versus Docetaxel in Patients with Advanced Non-Squamous Non-Small Cell Lung Cancer with Disease Progression On or After Platinum-Based Chemotherapy and Checkpoint Inhibitor Therapy (SAPPHIRE)

This is an open-label, randomized (1:1), multicenter, Phase 3 clinical trial evaluating the safety and efficacy of nivolumab in combination with investigational agent sitravatinib compared to docetaxel in patients with advanced non-squamous NSCLC who have previously experienced radiographic disease progression on or after treatment with platinum-based chemotherapy in combination with …

nivolumab
platinum-based chemotherapy
lung carcinoma
advanced non-squamous non-small cell lung cancer
non-squamous non-small cell lung cancer
  • 213 views
  • 28 Jul, 2021
  • 189 locations
featured
A Phase 1/1b Study of Sitravatinib in Combination with Nivolumab and Ipilimumab in Patients with Advanced or Metastatic Clear-Cell Renal Cell Carcinoma or Other Solid Malignancies

related RTKs including the TAM family (Tyro3/Axl/MERTK), VEGFR2, KIT, and MET. NIVO/IPI are monoclonal antibodies (mAbs) that inhibit the immune checkpoint proteins programmed death receptor-1 (PD-1

systemic therapy
carcinoma
nivolumab
ipilimumab
monoclonal antibodies
  • 27 views
  • 15 Sep, 2020
  • 1 location
featured
Phase 2 Study of Glesatinib, Sitravatinib or Mocetinostat in Combination With Nivolumab in Non-Small Cell Lung Cancer

Phase 2 Study of Glesatinib, Sitravatinib or Mocetinostat in Combination With Nivolumab in Non-Small Cell Lung Cancer

  • 356 views
  • 08 Nov, 2020
  • 2 locations
The TISA Trial - Senegal

This study evaluates the addition of a simple, scalable "WASH kit", including household water treatment products, a safe water storage container, and hygiene promotion, to the standard national

  • 0 views
  • 27 Jan, 2021
  • 1 location
Optimizing Antituberculosis Therapy in Adults With Tuberculous Meningitis

Kit (Zeesan Company, Xiamen). Participants with slow or intermediate acetylators will be administered with standard chemotherapy. For participants with rapid acetylators, patients were stratified at

  • 0 views
  • 05 Feb, 2021
  • 4 locations
Implementation Research of Kangaroo Mother Care in Rural Pakistan.

Pakistan has a high neonatal mortality rate (55/1000 live birth)(1) and each year more than 200,000 newborns die. In rural Pakistan, more than 50% deliveries occur at home and majority by unskilled birth attendants(2). The country has a high proportion of preterm births and according to unpublished data it ranges …

  • 1 views
  • 24 Jan, 2021
  • 2 locations
Point of Care Tests for Syphilis and HIV

This study will evaluate the performance of two point-of-care dual syphilis and HIV tests [Multiplo TP/HIV test (MedMira Inc, Halifax, Nova Scotia) and the INSTI Multiplex HIV-1/HIV-2/Syphilis Antibody Test (bioLytical Laboratories Inc., Richmond, BC)]. In addition to standard syphilis and HIV testing, point-of care testing (POCT) will be performed on …

hiv insti
hiv test
antibody test
  • 0 views
  • 25 Jan, 2021
  • 1 location
Safety Study of Etripamil Nasal Spray for Patients With Paroxysmal Supraventricular Tachycardia. NODE-303

NODE-303 is a multi-center, open label (OL) study to evaluate the safety of etripamil NS in patients with Paroxysmal Supraventricular Tachycardia (PSVT). Patients will be provided with an ambulatory Cardiac Monitoring System (CMS) to help document PSVT episodes. The CMS will be self-applied by the patient, when PSVT symptoms begin. …

  • 109 views
  • 27 Jan, 2021
  • 147 locations