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Found 142 clinical trials
HIV Vaccine in HIV-uninfected Adults (RV546)

The purpose of this study is to test whether delayed boosting (an extra administration of a vaccine) with the IHV01 (FLSC) protein and A244/AHFG with or without ALFQ will cause the body to make higher amounts of antibodies or different types of antibodies after the vaccination.

Accepts healthy volunteers
  • 0 views
  • 13 Mar, 2022
  • 1 location
Strategic Antiretroviral Therapy and HIV Testing for Youth in Rural Africa

The goal of this study is to evaluate the effect of a combination intervention on long-term HIV viral load (VL) suppression among HIV-infected adolescents and young adults 15-24 years of age. The study will take place in 28 rural HIV clinics in western Kenya and southwest Uganda. Clinics will be …

hiv viral load
antiretroviral agents
HIV Infection
antiretroviral therapy
hiv test
  • 0 views
  • 04 Feb, 2022
  • 2 locations
Optimizing HIV Virologic Outcomes for Pregnant Women in Uganda

The ENHANCED -SPS study is a before and after cluster randomized trial that will be conducted in 14 public health facilities providing HIV care in Southwestern Uganda. The study will evaluate the effectiveness of a multi-component intervention package that targets barriers to achieving optimal viral suppression among pregnant and postpartum …

  • 0 views
  • 23 Jan, 2021
  • 1 location
CombinADO: Evaluation of an Intervention Aimed at Improving HIV Outcomes Among Adolescents and Young Adults Living With HIV in Mozambique

This is a cluster-randomized trial designed to compare the effectiveness of the CombinADO strategy versus optimized standard of care (SOC) on viral suppression, antiretroviral therapy (ART) adherence and retention in HIV care among adolescents living with HIV (ALHIV) ages 10 to 24 years attending participating health facilities. Clinics are the …

antiretroviral therapy
HIV Vaccine
  • 0 views
  • 08 Oct, 2021
  • 1 location
Identifying Efficient Linkage Strategies for HIV Self-Testing

HIV self-testing (HIVST) has been found to be a highly acceptable approach for men to learn of their HIV status and has resulted in increased testing uptake. However, rates of antiretroviral therapy (ART) initiation among those tested with HIVST are difficult to capture. This clinical trial will test varying approaches …

antiretroviral therapy
HIV Vaccine
Accepts healthy volunteers
  • 0 views
  • 05 Dec, 2021
  • 1 location
Promoting Reductions in Intersectional StigMa (PRISM) - GHANA

HIV prevalence among men with have sex with men (MSM) in Ghana is at least eight times higher than that of the general population (2%). MSM in Ghana face high levels of stigma due to HIV status (actual or perceived), same-sex behavior, and gender non-conformity. These stigmas are documented barriers …

hiv test
HIV Vaccine
  • 0 views
  • 14 Jun, 2021
  • 1 location
The Welcome Incoming Neighbor (WIN) Community Trial

Migration is common in rural Africa: in-migrants have higher HIV incidence and prevalence than community residents, but underutilize combined HIV prevention and care services, including voluntary medical male circumcision and antiretroviral therapy, increasing the risks of HIV acquisition and onward transmission. Uptake of combined HIV prevention (CHP) is critical in …

antiretroviral therapy
HIV Vaccine
circumcision
  • 0 views
  • 09 Sep, 2021
  • 1 location
Pediatric HIV Disclosure Benefits Study (PhD-BS) - Sankofa 2

The purpose of this study is to conduct a pragmatic, stepped wedge cluster randomized trial in 12 HIV pediatric clinics in Ghana to determine effectiveness, health benefits, cost and implementation to inform scale-up and sustainability of pediatric disclosure.

hiv diagnosis
HIV Vaccine
  • 0 views
  • 23 Sep, 2021
  • 1 location
A Study of Switching to RPV Plus Other ARVs in HIV-1-infected Children (Aged 2 to <12 Years) Who Are Virologically Suppressed

The purpose of this study is to evaluate the steady state pharmacokinetics (PK) of rilpivirine (RPV) and determine the appropriate dose of RPV in combination with other antiretrovirals (ARVs) in participants aged greater than or equal to 2 to less than 12 years and to evaluate the safety and tolerability …

raltegravir
antiretroviral agents
dolutegravir
abacavir
emtricitabine
  • 61 views
  • 28 Apr, 2022
  • 5 locations
Validation of a Tuberculosis Treatment Decision Algorithm in HIV-infected Children

TB-Speed HIV is a prospective multicentre management study evaluating the safety and feasibility of the recently proposed PAANTHER TB treatment decision algorithm for HIV-infected children with presumptive TB. It will be conducted in four countries with high and very high TB (Tuberculosis) incidence (Cte d'Ivoire, Uganda, Mozambique, and Zambia) which …

tuberculosis
HIV Vaccine
  • 0 views
  • 29 Sep, 2021
  • 8 locations