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Found 155 clinical trials
Effects of Closed-loop Automatic Control of FiO2 in Extremely Preterm Infants

prolonged hypoxemic episodes are associated with retinopathy of prematurity (ROP), impaired long-term development and death. Closed-loop automated control of the inspiratory fraction of oxygen (FiO2-C

  • 0 views
  • 22 Jan, 2021
  • 2 locations
Preliminary Investigation of optimaL Oxygen Targets Trial

Mechanical ventilation of ICU patients universally involves titration of the fraction of inspired oxygen (FiO2) to maintain arterial oxygen saturation (SpO2). Despite decades of ICU practice

assisted ventilation
mechanical ventilation
FIO2
oximetry
  • 21 views
  • 24 Jan, 2021
  • 1 location
NHFOV vs NIPPV vs nCPAP in Preterm Infants With Respiratory Distress Syndrome

This will be a prospective, multi-center, three-arms,parallel, randomized, controlled trial with a superiority design,conducted in China. The investigators conduct this multi-centre, randomized, controlled trial to test the hypothesis that NHFOV is more effective than nCPAP or NIPPV in the treatment of respiratory distress syndrome (RDS) in infants with a gestational …

  • 0 views
  • 26 Jan, 2021
  • 8 locations
suPAR-Guided Anakinra Treatment for Management of Severe Respiratory Failure by COVID-19

The SAVE-MORE is a pivotal, confirmatory, phase III randomized clinical trial (RCT) aiming to evaluate the efficacy and safety of early start of anakinra guided by suPAR in patients with LRTI by SARS-CoV-2 in improving the clinical state of COVID-19 over 28 days as measured by the ordinal scale of …

  • 0 views
  • 19 Feb, 2021
  • 39 locations
LUS and Consequences of High FiO2 in Children

The purpose of this study is to evaluate effect of high FiO2 on the development of intraoperative atelectasis in mechanically ventilated children using LUS. to

  • 0 views
  • 28 Jan, 2021
  • 2 locations
Lowering PEEP: Weaning From High PEEP Setting

sum of two kind of venus-admixured. As it is known from classical physiology, the effects of FiO2 variations on PaO2 are deeply different depending on the type of venous admixures. In the case of a

pao2
FIO2
positive end expiratory pressure
  • 0 views
  • 26 Jan, 2021
  • 1 location
Comparison of High Flow Nasal Cannula (HFNC) Face-mask Non-Invasive Ventilation (NIV) & Helmet NIV in COVID-19 ARDS Patients

respiratory rate (RR) more than 30/min or oxygen saturation (SpO2) less than 90% or PaO2/FiO2 ratio less than 300 despite standard oxygen therapy by face mask (<15 L/min) who present to Royal hospital or

  • 0 views
  • 28 Jan, 2021
  • 1 location
High Flow Oxygen Therapy in Patients Suffering From Chronic Obstructive Pulmonary Disease Exacerbation: Effects and Mechanisms of Action

) heated air-oxygen mixture (FIO2 21-100%) through a dedicated nasal cannula and can be interesting in this context. This well tolerated technique improves oxygenation and decreases respiratory rate and

  • 0 views
  • 23 Jan, 2021
  • 1 location
CPAP in Liver Transplant

The purpose of this study is to determine the effectiveness of continuous positive airway pressure compared to standard treatment in preventing the need for intubation and mechanical ventilation in patients who develop acute hypoxemia after liver transplant. Hypoxemia complicates the recovery of 30-50 % of patients after abdominal surgery; endotracheal …

  • 4 views
  • 07 Nov, 2020
  • 1 location
Two Strategies of RDS Treatment in Newborns With Birth Weight > 1500 Grams

The purpose of this study is to compare two different treatment strategies for RDS in preterm infants > 1500 grams and evaluate whether a selective surfactant administration would reduce the need of intubation, mechanical ventilation and surfactant use.

pulmonary surfactant
intubation
mechanical ventilation
continuous positive airway pressure
oximetry
  • 2 views
  • 07 Nov, 2020
  • 2 locations