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Found 3315 clinical trials
Featured trial
The RADIANCE II Pivotal Study: A Study of the ReCor Medical Paradise System in Stage II Hypertension

The objective of the RADIANCE II Pivotal study is to demonstrate the effectiveness and safety of the Paradise System in subjects with Stage 2 hypertension on 0-2 medications at the time of consent. Prior to randomization, subjects will be hypertensive in the absence of hypertension medication.

angiography
antihypertensive therapy
hypertension
antihypertensive drugs
hypertensive medication
  • 932 views
  • 05 Dec, 2021
  • 83 locations
Featured trial
Hypertension Intracranial Pulsatility and Brain Amyloid-beta Accumulation in Older Adults (HIPAC Trial)

The aim of this study is to determine if lowering blood pressure using FDA approved medication (antihypertensive drugs) alters brain pulsatility and reduces brain amyloid beta protein accumulation in older adults. Amyloid beta protein is high in the brain of older adults with Alzheimer's disease. Hypertension may increase brain amyloid …

calcium
angiotensin ii
beta amyloid protein
antihypertensive drugs
electrocardiogram
  • 28 views
  • 16 Jun, 2021
  • 1 location
Featured trial
The Effect of Tirzepatide versus Dulaglutide on Major Adverse Cardiovascular Events in Patients with Type 2 Diabetes

We are currently recruiting participants for a clinical research study to evaluate the effectiveness of an investigational medication in type 2 diabetics who have had cardiovascular events including, but not limited to heart attack, stroke, cardiac stent placement or bypass, etc.

diabetes
type 2 diabetes
diabetes mellitus
type 2 diabetes mellitus
  • 41 views
  • 09 Aug, 2021
  • 1 location
Featured trial
Type 2 Diabetes Study – Seeking Volunteers Who Treat with Any Combination of Medications, Except Insulin.

We are currently seeking volunteers who are diagnosed with Type 2 Diabetes and who are treating with any combination of medications including any of the following:

  • 31 views
  • 08 Oct, 2021
  • 1 location
Featured trial
DIABETICS WITH FOOT ULCERS

A DIABETIC FOOT ULCER IS AN OPEN SORE OR WOUND THAT OCCURS IN APPROXIMATELY 15 PERCENT OF PATIENTS WITH DIABETES AND IS COMMONLY LOCATED ON THE BOTTOM OF THE FOOT.  

  • 56 views
  • 11 Sep, 2019
  • 1 location
Featured trial
Diabetic Gastroparesis Study

Diabetic gastroparesis creates feelings of bloating, nausea, vomiting and pain. If you have diabetes, ClinSearch is enrolling volunteers in a study testing an investigational medication.

  • 102 views
  • 23 Nov, 2020
  • 1 location
Featured trial
A multicenter, randomized, double-blind, placebo-controlled, parallel-arm study to assess the efficacy, safety, and tolerability of AVP-786 (deudextromethorphan hydrobromide [d6-DM]/quinidine sulfate [Q]) for the treatment of negative symptoms of schizophrenia

The purpose of this research is to evaluate the efficacy, safety and tolerability of AVP-786 compared to placebo for the treatment of negative symptoms of schizophrenia. Negative symptoms of schizophrenia can include difficulty in displaying emotion through facial expressions, apathy (lack of interest), slowed speech production, loss of ability to …

  • 0 views
  • 05 Apr, 2021
  • 1 location
Featured trial
Inflammatory Characterization of Known or Possible Cardiovascular Diseases

Background: Cardiometabolic diseases are a combination of medical disorders that, when they occur together, increase the risk of heart disease and diabetes

diabetes
fats
heart disease
  • 46 views
  • 23 Nov, 2020
  • 1 location
Featured trial
A Phase 3, multicenter, randomized, double-blind, placebo-controlled, parallel-design study to assess the efficacy, safety, and tolerability of AVP-786 (deudextromethorphan hydrobromide [d6-DM]/quinidine sulfate [Q]) for the treatment of agitation in patients with dementia of the Alzheimer’s type.

Evaluate the efficacy, safety, and tolerability of AVP-786 compared to placebo, for the treatment of agitation in patients with dementia of the Alzheimer's type.  

dementia
donepezil
rivastigmine
agitation
galantamine
  • 14 views
  • 08 Dec, 2020
  • 1 location
Featured trial
Human Translational Studies of Inflammation and Cardiometabolic Diseases: The Psoriasis, Atherosclerosis and Cardiometabolic Disease (PACI) Initiative

diabetes. One disorder, psoriasis, is an inflammation that mostly affects the skin but can affect the entire body. Another disorder, atherosclerosis, is a process in which cholesterol is gradually deposited

diabetes
cholesterol measurement
heart disease
atherosclerosis
  • 61 views
  • 23 Nov, 2020
  • 1 location