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Found 896 clinical trials
Cut-off Values of 6-min Walk Test and Sit-to-stand Test for Determining Functional Status in Atrial Fibrillation

Cut-off values indicating reduced functional status in 6-min walk test and 30-second sit-to-stand test in patients with atrial fibrillation will be determined in the study.

  • 11 Mar, 2021
  • 1 location
Psychophysical Studies of Cancer Therapy Pain

The Aim of this Study is to examine the feasibility of using quantitative sensory testing procedures, widely applied to the experimental study of sensory processing in humans both with and without various pain syndromes, to now characterize the psychophysical properties of neuropathic pain that has developed as a consequence of …

pain relieving
moderate pain
cancer treatment
  • 11 Apr, 2021
  • 1 location
Pre- and Post-treatment Lung Microbiota Metabolome and Immune Signatures at the Site of Disease in Patients With Active Pulmonary Tuberculosis

The diverse microbial communities in different parts of the human body (microbiome) are important for health but understudied in pulmonary tuberculosis (TB), which is the single biggest infectious cause of death in the world. The investigators will study the site-of-disease microbiome (in the lung bronchoalveolar space) in TB cases to …

  • 10 Apr, 2021
  • 3 locations
PROSAIC-19 - Prospective Longitudinal Assessment in a COVID-19 Infected Cohort

DESIGN Longitudinal prospective observational multicentre study. Primary objective: Understand the immune mechanisms driving COVID-19 disease in patients with a history of lung disease

blood test
pulmonary disease
  • 25 Jan, 2021
  • 1 location
Examining Racial and SocioEconomic Disparities (ERASED) in Chronic Low Back Pain Study

It remains unclear whether certain disadvantaged subgroups of society may be at heightened risk for poor chronic low back pain (cLBP) outcomes. The overall aim of this study is to incorporate a socioeconomic framework to characterize racial differences in cLBP severity and disability. Further, guided by the theory of fundamental …

low back pain
  • 24 Jan, 2021
  • 1 location
Food Intake Response to Short-Term Modifications of Metabolism in Humans

One reason people gain weight is eating more calories from food than what they need for energy over 24 hours. Metabolism is the amount of energy a person uses over 24 hours. Researchers want to study the relationship between changes in metabolism and how much a person eats. Objectives To …

blood test
  • 12 Mar, 2021
  • 1 location
Differential Expression of Cytokines Transcriptome and miRNA in Coronavirus Disease 2019 (COVID-19) Egyptian's Patients

The aim of this effort is to study host-pathogen interaction in Egyptian patients infected with COVID-19. The investigators will perform genome-wide miRNA and transcriptome screens in the infected patients along with healthy ones for comparison. All types of cytokines play pivotal roles in immunity, including the responses to different viral …

  • 26 Jan, 2021
  • 2 locations
NHALES (Natural History of Asthma With Longitudinal Environmental Sampling)

Background Asthma is a serious clinical and public health problem. Researchers want to collect data to better understand how bacteria and other things in the environment can affect people's asthma. Eligibility Nonsmoking adults age 18 - 60 who have moderate to severe asthma and are not pregnant or breastfeeding. Design …

chest tightness
  • 21 Mar, 2021
  • 1 location
Bronchial Asthma and Diabetes: Impact on Bronchial Inflammation and Exercise Capacity

Type 2 diabetes is the most common form of diabetes and according to several studies, even lung can represent another target of the diabetic disease. Asthmatic patients often show comorbidities and obesity is one of the main.Several studies in literature suggest that patients with higher Body Mass Index (i.e. overweight …

body mass index
eosinophil count
  • 25 Jan, 2021
  • 1 location
The Impact of Insomnia on Pain in HIV

The overall objective of this application is to investigate the impact of insomnia on pain, physical functioning, and inflammation in people living with HIV. The two aims of this study to determine 1) whether insomnia promotes increased sensitivity and inflammatory reactivity to pain stimuli, and 2) if weekly fluctuations in …

sleep disorder
hiv diagnosis
antiretroviral agents
antiretroviral therapy
psychiatric disorder
  • 23 Jan, 2021
  • 1 location