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Found 124 clinical trials
Frequency and Clinical Phenotype of BAP1 Hereditary Predisposition Syndrome

This research will have a significant impact on the overall management of those cancer patients and their family members who are at risk for hereditary cancer due to germline inactivation of BAP1. Our study will ultimately facilitate the development of novel screening, prevention and treatment strategies for these individuals with …

Accepts healthy volunteers
  • 20 Jul, 2022
  • 1 location
of Androgen Receptor Expression in Breast Cancer With or Without BRCA Mutation

Androgen Receptor is extensively expressed in BRCA and its role in the disease may differ depending upon molecular subtypes and stages. Androgen Receptor (AR) may act as an antagonist of estrogen receptor α (ERα), in ERα induced effect, whereas in the absence of estrogens, AR may act as an agonist, …

estrogen receptor
  • 17 Jun, 2022
  • 1 location
TRIple Negative Breast Cancer Markers In Liquid Biopsies Using Artificial Intelligence

Triple negative breast cancer (TNBC) is the most aggressive of breast cancers and it is usually treated with chemotherapy even before surgery. In many cases, the chemotherapy completely "melts" the tumor and these patients do well. When the tumor is not eliminated by the chemotherapy, the patient receive more chemotherapy …

  • 14 May, 2021
  • 4 locations
Quality Control Study of MR Based Screening of Individual With Increased Risk for Pancreas Cancer.

Early detection of pre-cancerous lesions or early stage pancreatic cancer seems to have a positive impact in survival for patients with an increased genetic risk to develop pancreas cancer. In this study, following the indication of the swedish guidelines, consecutive patients with a family history for pancreas cancer underwent a …

  • 23 Jan, 2021
  • 1 location