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Found 171 clinical trials
LIquid BIopsies in Patients Presenting Non-small Cell Lung Cancer

The goal of this project is to characterize the genetic profile of patients with advanced stage IIIB/IV non-small cell lung cancer (NSCLC) using liquid biopsies

erbb2
epidermal growth factor receptor
BRAF
RET
proto-oncogene tyrosine-protein kinase ros
  • 21 views
  • 13 Oct, 2021
  • 12 locations
Molecular Targets for the Treatment of Histiocytosis (TARGET-HISTIO)

The primary objective: to develop technical and operating procedures for detection mutations of histiocytosis during clinical practice of no-specialized molecular platforms, for diagnosis and follow-up of the disease. The secondary objectives: to describe therapeutic target mutations in histiocytosis patients, and to develop the cellular tests to evaluate in vitro the …

  • 0 views
  • 01 Jul, 2022
  • 2 locations
Encorafenib and Cetuximab in Patients With Metastatic, BRAFV600E-mutated, Colorectal Carcinoma: a Multi-centric, Multi-national, Prospective, Longitudinal, Non-interventional Study in Germany, Austria and Switzerland (BERING-CRC)

months for patients with BRAF wild-type tumours. After 1st line therapy, treatment outcomes with standard therapy are poor in patients with BRAF-mutated mCRC, with response rates (ORR) of ≤ 11%, a median

  • 0 views
  • 14 Oct, 2022
  • 14 locations
Selective Internal Radiation Therapy With 90Y Resin Micropheres for Refractory Colorectal Cancer Liver Metastases (SIRT)

Observational, feasibility study investigating biological aspects in patients with liver metastasis from colorectal cancer undergoing treatment with SIRT, by translational analysis of biological samples.

  • 0 views
  • 22 Mar, 2022
  • 1 location
Sub-type Specific Genomic Mutations in sBOTs

The aim of this study is to identify different origin in carcinogenesis between serous borderline ovarian tumors presenting a. without implants, b. with non-invasive implants, c. with invasive implants and d. with micropapillary pattern. The presence of specific mutations could suggest for a more aggressive primary treatment if a higher …

  • 0 views
  • 02 Nov, 2021
  • 1 location
Clinical and Molecular Study With Digital Support of Patients With Inoperable Lung Cancer (SNF-CLIMEDIN)

The purpose of this study is to provide high quality oncology services to patients with inoperable Non-Small Cell Lung Cancer (NSCLC) in Greece. These services will be based on 3 pillars Clinical: personalized treatment will be administered and its effectiveness and safety will be recorded and evaluated. Molecular: the gene …

  • 0 views
  • 24 May, 2022
  • 15 locations
Mapping of Tumor Stem Cells in the Resection Marigin During Extirpation of Highly Malignant Gliomas Using GlioStem (CeNo2)

The study investigates the occurance of GlioStem positive tumor stem cells in the rescection marigins of hig grade human gliomas

  • 0 views
  • 12 Oct, 2022
  • 1 location
Clinical Evaluation of Genetron TERT/BRAF PCR Kit in Thyroid Cancer Patients

The purpose of this trail is to evaluate the performance of Genetron TERT/BRAF PCR Kit in Thyriod Cancer patients using real-time PCR method.

KIT
  • 0 views
  • 16 Jun, 2022
  • 4 locations
Pan-Canadian Lung Cancer Observational Study (PALEOS)

), exon 20 EGFR mutation, MET and BRAF patients, with the goal of expanding into other rare molecular alterations within year 2

HER2
lung cancer
ROS1
lung carcinoma
cancer
  • 1 views
  • 14 Jul, 2022
  • 1 location
Binimetinib Plus Encorafenib Real Life Investigation of Next Generation Melanoma Treatment (BERING)

binimetinib in unresectable advanced or metastatic BRAF(Rapidly Accelerated Fibrosarcoma isoform B)-V600-mutant malignant melanoma after commercial availability of these two products in Germany, Austria and

cancer
BRAF
  • 1 views
  • 17 Feb, 2022
  • 66 locations