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Found 67 clinical trials
Precision-Based Genomics in Prostate Cancer

Background Prostate cancer is the most common cancer and the second leading cause of death in males in the United States. Researchers want to find additional gene mutations that may increase a man s risk for prostate cancer and may affect how aggressive the disease is. Objective To look at …

  • 25 Jul, 2022
  • 1 location
Observatory of Prolymphocytic Leukemia T

as JAK STAT axis inhibitors, anti-AKT, or anti BCL2 . Main objective: Better manage prolymphocytic T leukemias. Secondary objectives: Molecular characterization of

monoclonal antibodies
  • 24 Jan, 2021
  • 1 location
NGS in Gallbladder Cancer and Response to Treatment

Evidence suggests distinct models of molecular and pathologic progression, and a growing body of genetics data points to a heterogeneous collection of underlying mutations in key oncogenes and tumor suppressor genes. Although tumor genetics have been used to tailor individual treatment regimens and guide clinical decision making in other cancers, …

  • 18 Jun, 2022
  • 1 location
of Androgen Receptor Expression in Breast Cancer With or Without BRCA Mutation

Androgen Receptor is extensively expressed in BRCA and its role in the disease may differ depending upon molecular subtypes and stages. Androgen Receptor (AR) may act as an antagonist of estrogen receptor α (ERα), in ERα induced effect, whereas in the absence of estrogens, AR may act as an agonist, …

estrogen receptor
  • 17 Jun, 2022
  • 1 location
Identification of miRNAs Associated With Gender Difference in Osteoarthritis Patients (MIRGOA)

The biological study involves the collection of samples from male and female patients (intraoperative waste tissue, blood and synovial fluid), suffering from mild and moderate-severe OA, who undergo endo or arthro-prosthesis surgery, or arthroplasty, for the identification and characterization of a panel of "gender-specific" miRNAs. MicroRNAs will be extracted from …

joint reconstruction
  • 06 Apr, 2022
Prediction of Aortic Dilatation and Rupture

Aortic aneurysm is a very common incidental finding in the diagnostic imaging of the chest. It is especially common in middle aged men (up to 40 %). It is called as a silent killer, since it can lead to aortic dissection and rupture without pre-existing symptoms. Mortality of rupture can …

  • 10 Oct, 2021
  • 1 location
Maternal Hypertriglyceridaemia Study

Besides maternal hyperglycemia, a strong link between maternal pregravid weight/maternal triglyceride(Tg) levels and fetal growth/childhood obesity/metabolic syndrome in offspring has been demonstrated in largely Caucasian populations. This study aims to explore the link between maternal hypertriglyceridemia and offspring health in Asians.

hemoglobin a1c
oral glucose tolerance test
  • 21 Jan, 2021
  • 1 location