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Found 599 clinical trials
VRC 611: Human Monoclonal Antibody (mAb) VRC-HIVMAB0102-00-AB (CAP256V2LS)Administered Via Subcutaneous and Intravenous Injection in Healthy Adults

Background HIV is a serious disease with no cure or vaccine to prevent it. Using antibodies could be a way to prevent HIV infection. Antibodies are made by the human body to fight germs. Researches want to test an antibody, CAP256V2LS. Objective To test CAP256V2LS to see if it is …

Accepts healthy volunteers
  • 10 views
  • 19 Jun, 2022
  • 1 location
A Study to See if Low Level Laser Light Can Help to Treat Toenail Fungus

The purpose of this study is to determine whether low level laser therapy (LLLT) using the Erchonia LunulaLaser device is effective in clearing toenails with onychomycosis.

  • 2266 views
  • 28 Jan, 2022
  • 1 location
Improving Informed Consent for Early Phase Anti-Cancer Trials (CONSENT)

The purpose of the trial will be to test whether providing both a short summary PIS and a link to a set of online video modules will improve patient understanding (those considering early phase clinical trials) as measured on the Quality of Informed Consent questionnaire (Part A), as compared to …

  • 0 views
  • 17 Mar, 2022
  • 1 location
Efficacy and Safety of On-demand and Continuous Administration of Nasal Spray in the Treatment of Allergic Rhinitis

WHO recommend to divide AR into 4 subgroups according to the symptom frequency (intermittent or persistent) and severity (mild or moderate-to-severe). For the persistent moderate-to-severe AR subgroup, the guideline suggests to treat with intranasal corticosteroid (INS) plus antihistamines (AH1) for 2-4 weeks. If the symptom is controlled then degrade the …

  • 0 views
  • 11 May, 2022
Evaluation of a New Bladder Health Mobile Application in Pregnancy (BHmApp)

Millions of women experience involuntary loss of urine called urinary incontinence (UI). UI can be slightly bothersome or totally debilitating. Women experience UI twice as often as men. Urinary incontinence can also be a persistent condition caused by underlying physical problems or changes, including pregnancy and childbirth. UI symptom severity …

Accepts healthy volunteers
pelvic floor muscle training
  • 14 views
  • 27 May, 2022
  • 1 location
Fixed Versus Adjustable Loop in ACL Reconstruction

Study Aims and Objectives: To investigate the following null hypothesis: that there is no difference in clinical and functional outcome when comparing outcomes of Anterior Cruciate Ligament (ACL) reconstruction when comparing femoral side graft fixation with either a fixed versus an adjustable suspensory loop system. The research team will achieve …

knee joint laxity
autograft
meniscal tear
anterior cruciate ligament injury
  • 8 views
  • 29 Jan, 2022
  • 1 location
Traditional Versus Alternative Alignment in TKR

As many as 20% of patients are unhappy with the results of total knee replacement (TKR). Various changes to surgical technique have tried to address this but have not led to a significant improvement in the numbers of patients satisfied with their operation. Recently, attention has focussed on alignment of …

Accepts healthy volunteers
  • 0 views
  • 30 May, 2022
  • 1 location
Remote Hearing Aid Adjustment for New Hearing Aid Users; a Randomised Controlled Trial (RCT) (RCT)

Many hearing aid users experience substantial communication difficulties that may affect their participation in daily life situations negatively. One of the reasons for experiencing remaining problems could be due to unrealistic expectations, another reason could be that the hearing aid is not well adjusted or that the hearing aid user …

Accepts healthy volunteers
  • 0 views
  • 10 May, 2022
  • 1 location
The Basel BOMP-AID Randomized Trial (BOMP-AID)

Delirium is a neurobehavioural syndrome that frequently develops in the postoperative and/or ICU setting. The incidence of elderly patients who develop delirium during hospital stay ranges from 11-82%. Delirium was first described more than half a century ago in the cardiac surgery population, where it was already discovered as a …

  • 1 views
  • 21 Mar, 2022
  • 1 location
Permanent Resin Restorations Fabricated by Three Dimension Printer

Additive manufacturing (AM) and 3D printing (3DP) technologies have advanced significantly in many different areas. With the time and cost advantage it provides in low-volume production, 3D printing technologies also come to the fore in the field of digital dentistry. A tooth-coloured, ceramic-filled permanent resin has been introduced by the …

Accepts healthy volunteers
  • 0 views
  • 02 Jan, 2022
  • 1 location