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Found 21 clinical trials
Isisekelo Sempilo Trial to Optimize Peer (Thetha Nami) Delivery of HIV Prevention to Young People in Rural KwaZulu-Natal

Despite advances in efficacious, efficient and safe biomedical tools to reduce HIV transmission and acquisition the HIV epidemic in South Africa(SA) remains an intractable problem, with the lifetime risk of infection approaching 70% for a 15-year-old girl currently living in northern KwaZulu-Natal, the Africa Health Research Institute(AHRI) research setting. This …

Accepts healthy volunteers
  • 0 views
  • 10 Mar, 2022
  • 1 location
Digital Limited Interaction Efficacy Trial of LifeSkills Mobile to Reduce HIV Incidence in YTW (LifeSkills)

The LifeSkills Mobile app will be evaluated in a randomized controlled trial (RCT) among 5,000 young transgender women (YTW), ages 16-29 in the United States (U.S.). Study findings will demonstrate if the intervention will reduce HIV incidence.

Accepts healthy volunteers
  • 0 views
  • 28 Jul, 2022
  • 1 location
Peer PrEP Referral + HIV Self-test Delivery for PrEP Initiation in Kenya (PeerPrEP)

Few young women at risk of HIV infection are initiating pre-exposure prophylaxis (PrEP) for HIV prevention in Kenya, thus we propose refining and testing a new model to increase PrEP initiation among young women at high HIV risk that has never been explored: peer PrEP referral + HIV self-test (HIVST) …

Accepts healthy volunteers
  • 0 views
  • 15 Mar, 2022
Randomized Controlled Trial of Game Changers

The study is a randomized controlled trial (RCT) of Game Changers, an 8-session peer-led group intervention that aims to empower and mobilize people living with HIV (PLWH) to be agents for HIV prevention in their social networks.

  • 0 views
  • 26 Mar, 2022
  • 1 location
Optimizing PrEP Utilization Among Alcohol and Other Drug (AOD) Using Women of Color

Nationally, the HIV case rate among black/ African American (AA) women is nearly 20 times higher than in white women; for Hispanic/Latino women it is 4.5 times higher. Moreover, according to findings in the HIV Prevention Trials Network (HPTN) Study 064 (The Women's HIV SeroIncidence Study), HIV incidence among women …

Accepts healthy volunteers
  • 62 views
  • 12 Feb, 2022
  • 1 location
Reducing Intersectional Stigma Among High-Risk Women in Brazil to Promote Uptake of HIV Testing and PrEP (PRISM Brazil)

This is a randomized controlled trial of a multi-level intervention to prevent HIV acquisition among transgender women (N=400) in São Paulo, Brazil. The intervention will be evaluated using a randomized wait-list controlled trial to compare uptake of HIV testing (self-testing and clinic-based) (Aim 1), PrEP initiation and persistence (Aim 2), …

Accepts healthy volunteers
  • 0 views
  • 20 Jun, 2022
Preventing HIV Among Native Americans Through the Treatment PTSD & Substance Use

Investigators will conduct a two-arm, comparative effectiveness randomized controlled trial of two culturally adapted, empirically based programs (EBP) - Narrative Exposure Therapy (NET) vs. Motivational Interviewing with Skills Training (MIST) in terms of lowering HIV sexual-risk behaviors (HSB) for American Indian / Alaska Native (AIAN) men and women. NET addresses …

Accepts healthy volunteers
  • 33 views
  • 11 Jul, 2022
  • 1 location
Podcasting HIV Prevention Within African American Communities

Given the continued impact of HIV among African Americans, there is still an urgent need to expand prevention efforts and HIV testing in African American communities. Heterosexual individuals may acquire and spread infection directly through heterosexual contact, bi-sexual sexual contact, and/or indirectly through homosexual sexual contact. Evidence-based interventions (EBIs) have …

Accepts healthy volunteers
  • 2 views
  • 28 May, 2022
  • 1 location
Tenofovir Rectal Douche to Prevent HIV Transmission Among Adolescents (ATN DREAM)

ATN DREAM is an early phase-1, open label study to examine the safety, pharmacokinetics (PK), pharmacodynamics (PD), and acceptability of a one-dose tenofovir (TFV) medicated douche. The overall goal is to inform the design of an extended safety study of an on-demand and behaviorally congruent TFV douche to confer protection …

Accepts healthy volunteers
  • 0 views
  • 14 May, 2022
  • 1 location
Addressing Health Disparities in Engagement, Retention, and Utilization of PrEP Among South Florida Women of Color

Women of color (WOC) in South Florida, the region with the highest HIV rates in the U.S., experience significant barriers to accessibility, uptake, and utilization of Pre-exposure prophylaxis (PrEP) for HIV prevention, despite FDA approval since 2012. The purpose of this study is to use a Community-Based Participatory Research (CBPR) …

Accepts healthy volunteers
  • 0 views
  • 03 May, 2022
  • 3 locations