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Found 18 clinical trials
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The PrEPARE Project: Prevention Empowering and Protecting Young Women in South Africa

The project seeks to determine whether implementing a multilevel, woman-focused intervention, the Young Women's Health CoOp (YWHC), for pre-exposure prophylaxis (PrEP) readiness, uptake, and adherence is a viable complement to the HIV prevention plan for the Government of South Africa. Specifically, this project aims to: increase uptake, of sexual and …

  • 4 views
  • 29 Jan, 2021
  • 1 location
None
Biomedical HIV/AIDS Prevention Program Yunnan

B-HAPPY is an implementation project to study the process by which pre-exposure prophylaxis (PrEP) is introduced and integrated into a specific international health system facing high rates of HIV incidence among men who have sex with men. The study will use a stepped wedge design to compare implementation outcomes across …

  • 0 views
  • 30 Apr, 2021
  • 1 location
None
Pharmacy Delivery to Expand the Reach of PrEP in Kenya

A pilot study to test a novel model for PrEP initiation and refills in Kenya: pharmacy-based PrEP delivery.

  • 0 views
  • 20 Feb, 2021
  • 2 locations
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Preventing HIV Among Native Americans Through the Treatment PTSD & Substance Use

Investigators will conduct a two-arm, comparative effectiveness randomized controlled trial of two culturally adapted, empirically based programs (EBP) - Narrative Exposure Therapy (NET) vs. Motivational Interviewing with Skills Training (MIST) in terms of lowering HIV sexual-risk behaviors (HSB) for American Indian / Alaska Native (AIAN) men and women. NET addresses …

Accepts healthy volunteers
  • 9 views
  • 05 Oct, 2021
  • 1 location
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The Shauriana Intervention for GBMSM in Kenya

The Shauriana intervention, developed from qualitative work using a community-based participatory approach, aims to integrate PrEP, sexual health, and mental health support for gay, bisexual, and other men who have sex with men in Kenya. This study consists of a brief pilot test phase with 10 participants, followed by a …

  • 0 views
  • 26 Jan, 2021
  • 1 location
None
Optimizing PrEP Utilization Among Alcohol and Other Drug (AOD) Using Women of Color

Nationally, the HIV case rate among black/ African American (AA) women is nearly 20 times higher than in white women; for Hispanic/Latino women it is 4.5 times higher. Moreover, according to findings in the HIV Prevention Trials Network (HPTN) Study 064 (The Women's HIV SeroIncidence Study), HIV incidence among women …

  • 42 views
  • 27 Aug, 2021
  • 1 location
None
Reducing Intersectional Stigma Among High-Risk Women in Brazil to Promote Uptake of HIV Testing and PrEP

This is a randomized controlled trial of a multi-level intervention to prevent HIV acquisition among transgender women (N=400) in So Paulo, Brazil. The intervention will be evaluated using a randomized wait-list controlled trial to compare uptake of HIV testing (self-testing and clinic-based) (Aim 1), PrEP initiation and persistence (Aim 2), …

  • 0 views
  • 03 Feb, 2021
None
An Acceptance Based PrEP Intervention to Engage Young Black MSM in the South

Investigators will use a generalized framework for the adaptation of EBIs to inform the development of a brief Acceptance and Commitment Therapy (ACT)-based culturally appropriate pre-exposure prophylaxis (PrEP) intervention tailored to young Black men who have sex with men (YBMSM), named ACTPrEP.

Accepts healthy volunteers
  • 0 views
  • 28 Oct, 2021
  • 1 location
None
Evaluating Distribution of a Tenofovir Douche With Tap Water Douching and Simulated Receptive Anal Intercourse

DREAM-02 is a phase 1, open label study to evaluate different sequences of tap water douching and simulated receptive anal intercourse (sRAI) in the presence of a tenofovir douche designed to confer protection from Human Immunodeficiency Virus (HIV) acquisition. DREAM-02 will assess the safety and pharmacokinetics (PK) of different sequences …

Accepts healthy volunteers
  • 0 views
  • 03 Oct, 2021
  • 1 location
None
Long-acting Biomedical HIV Prevention in Transgender Women

Transgender women (TW) have unique challenges related to HIV prevention medication adherence. Left unaddressed, these challenges will prevent TW from accessing the promising long-acting HIV prevention tools in the development pipeline. This study will develop a replicable process to tailor the delivery of these tools and an adherence intervention (that …

  • 0 views
  • 09 Jul, 2021