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Found 33 clinical trials
Featured trial
Pilot Study of Topical Dexamethasone 0.01% Solution for Prevention of Oral Chronic Graft Versus Host Disease

at each visit). Review of medications (at each visit). ACTH stimulation test to evaluate adrenal gland function (at 3 months). Patients are given an injection of a drug called "ACTH

graft versus host disease
graft-versus-host disease
  • 160 views
  • 22 Dec, 2020
  • 1 location
Featured trial
Re-assessment of diagnostic cortisol values for adrenal insufficiency using a highly specific cortisol assay

The adrenal glands are small organs that are located on top of each kidney. Normally, the adrenal glands make substances called hormones. The adrenal gland produces several different hormones that have specific functions in the body. One of these hormones is cortisol. Among other functions, cortisol in the blood helps …

Accepts healthy volunteers
  • 0 views
  • 08 Jan, 2022
  • 1 location
Featured trial
A Phase 2 Double-Blind, Placebo Controlled Multi-Center Study to Evaluate the Efficacy and Safety of Tcelna in Subjects With Secondary Progressive Multiple Sclerosis

A Phase 2 Double-Blind, Placebo Controlled Multi-Center Study to Evaluate the Efficacy and Safety of Tcelna in Subjects With Secondary Progressive Multiple Sclerosis

  • 204 views
  • 08 Nov, 2020
  • 1 location
Adrenocorticotropic Hormone (ACTH) for Post-op Inflammation in Proliferative Vitreoretinopathy (PVR)

-operative proliferative vitreoretinopathy patients receiving subcutaneous injections of H.P. Acthar®, an adrenocorticotropic hormone (ACTH) analog. The study will be conducted at the Wilmer Eye Institute

  • 6 views
  • 25 Mar, 2022
  • 1 location
A Clinical Study to Evaluate the Potential Role of ACTH Gel in Patients With Scleritis (ATLAS)

ATLAS study is a clinical trial to evaluate the potential role of subcutaneous adrenocorticotropic hormone (ACTH) gel in the management of non-infectious scleritis. Specifically, the

  • 68 views
  • 28 Jul, 2022
  • 3 locations
Psilocybin Versus Ketamine in Treatment-Resistant Depression (PSIKET_001)

will explore the role of plasmatic neurobiological biomarkers in depression (BDNF, prolactin, ACTH and oxytocin).

  • 0 views
  • 03 Jun, 2022
  • 1 location
Adrenalectomy Versus Follow-up in Patients With Subclinical Cushings Syndrome (AUSC)

Incidental findings of adrenal tumours,"incidentalomas", occur in 1-5 % in the general population and 10-25 % of these patients will exhibit biochemical mild hypercortisolism. Although the patients do not have clinical signs of classical Cushing's syndrome, they have an increased risk for hypertension, dyslipidemia, diabetes mellitus, osteoporosis and obesity. The …

  • 30 views
  • 24 Mar, 2022
  • 3 locations
Phase I Study of AZD5363 + Olaparib + Durvalumab in Patients With Advanced or Metastatic Solid Tumor Malignancies

This is a Phase 1 dose-escalation study to evaluate the safety and tolerability of combination treatment of AZD5363 + Olaparib + Durvalumab and to determine the RP2D in patients with advanced or metastatic solid tumor malignancies. The purpose of this trial is to determine if combination treatment of drugs, Olaparib, …

  • 0 views
  • 22 Jan, 2021
  • 1 location
Rapid Recognition of Corticosteroid Resistant or Sensitive Sepsis (RECORDS)

Main objective and primary endpoint: To compare the effect hydrocortisone plus fludrocortisone vs. placebo on a composite of death or persistent organ dysfunction - defined as continued dependency on mechanical ventilation, new renal replacement therapy, or vasopressors - assessed at 90 days on intensive care unit (ICU) adults and having …

acute respiratory distress syndrome
lactate level
septic shock
dopamine
positive end expiratory pressure
  • 0 views
  • 23 May, 2022
  • 1 location
Outcomes of AVS With or Without ACTH Stimulation in PA

To compare the effect of different procedures of AVS(with or without ACTH stimulation) on the long-term outcomes of patients with PA

  • 0 views
  • 03 Sep, 2021
  • 1 location