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Found 3 clinical trials
Actuate 1901: 9-ING-41 in Myelofibrosis

9-ING-41 has anti-cancer clinical activity while not causing myelosuppression, and has both pre-clinical anti-fibrotic activity and activity against myelofibrosis. This Phase 2 study will study

neutrophil count
stem cell transplantation
ruxolitinib
cancer
  • 17 views
  • 19 Mar, 2021
  • 10 locations
9-ING-41 in Pediatric Patients With Refractory Malignancies.

9-ING-41 has anti-cancer clinical activity with no significant toxicity in adult patients. This Phase 1 study will study its efficacy in paediatric patients with advanced malignancies.

beta-hcg
cns tumor
stem cell infusion
pleural effusion
cyclophosphamide
  • 0 views
  • 01 Aug, 2021
  • 9 locations
9-ING-41 in Patients With Advanced Cancers

GSK-3 is a potentially important therapeutic target in human malignancies. The Actuate 1801 Phase 1/2 study is designed to evaluate the safety and efficacy of 9-ING-41, a potent GSK-3 inhibitor

paclitaxel
solid tumors
corticosteroids
lomustine
HER2
  • 542 views
  • 01 Aug, 2021
  • 16 locations