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Found 6 clinical trials
Study of the Breast Milk Microbiota and Its Influence on the Development of Early and Late Neonatal Bacterial Sepsis Under Three Months of Age. (MINEOS)

principle of "Microbial Culturomics" and targeted metagenomics (16S ribosomal RNA gene sequencing).

blood culture
bacterial infection
  • 04 Oct, 2022
  • 1 location
Exocrine Pancreatic Insufficiency After Acute Pancreatitis and Pancreatic Enzyme Replacement Therapy

Acute pancreatitis represents an acute inflammatory process of the pancreas, which undergoes local and systemic complications, associated with non-negligible morbidity and mortality, and significant economic and quality of life impact. Even after the recovery phase, the development and persistence of sequelae from the inflammatory/necrotic process, including exocrine and endocrine pancreatic …

  • 04 Oct, 2022
  • 1 location
Severe Asthma Exacerbations and Mepolizumab Treatment (ESAM-BIO)

This is a hypothesis-generating project to investigate a) infective etiology and b) inflammatory profile of the exacerbations of asthma in severe asthmatic patients treated with the humanized monoclonal antibody against interleukin-5 Mepolizumab. Under these treatment conditions the study will inform on the relationship between these two axes: infection & innate …

  • 27 May, 2022
  • 1 location
Gut Microbiome in Inflammatory Bowel Disease

Inflammatory bowel disease (IBD) is a chronic inflammatory condition for gastrointestinal tract. There have been numerous studies to reveal dysbiosis of fecal/mucosal microbiome composition in IBD patients but actual trend of dysbiosis is strikingly different among patient's ethnicity. In this background, the investigators have composed a prospective cohort of Korean …

crohn's disease
inflammatory bowel disease
ulcerative colitis
  • 21 Mar, 2022
  • 1 location
Genomics and Metagenomics of Asthma Severity (GEMAS)

The Genomics and Metagenomics of Asthma Severity (GEMAS) study aims to assess the role of genomics, the microbiome, and the interaction between them in the development of asthma exacerbations in European patients with asthma.

  • 29 May, 2022
  • 5 locations
The Sinonasal Cavity as a Reservoir for Upper Airway Bacterial Development

While the maternal-newborn exchange of airway microbiota is well-documented, no studies have examined within-subject relationships among the mouth, sinuses, nasopharynx and lungs and the relative abundance of bacterial taxa at those sites. Recent evidence suggests the oral cavity may serve as a reservoir for pathogens that translocate to non-oral locations; …

sweat test
  • 19 Apr, 2022
  • 1 location