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Found 58 clinical trials
Multicentre Investigation of Novel Electrocardiogram Risk Markers in Ventricular Arrhythmia Prediction (MINERVA)

test will be performed whilst measuring a 12-lead ECG and will be correlated with event rates to establish their effectiveness in predicting arrhythmia risk. The minimum follow up period should be 18

primary prevention
cardiac resynchronization therapy
  • 38 views
  • 23 Feb, 2022
  • 5 locations
Utilising Lifemap to Investigate Malignant Arrhythmia Therapy

), measures the degree of heterogeneity in electrical restitution using data obtained from a standard 12 lead ECG acquired during an invasive electrophysiological study. In an ischaemic cardiomyopathy

electrocardiogram
arrhythmia
12 lead ECG
cardiomyopathy
ventricular arrhythmia
  • 24 views
  • 26 Jan, 2021
  • 1 location
Systemic, Pancoronary and Local Coronary Vulnerability (VIP)

The aim of the VIP study is to investigate the impact of vulnerability markers (inflammatory serum biomarkers for systemic vulnerability, coronary shear stress and vulnerability mapping for pancoronary vulnerability, and imaging-based plaque features for systemic vulnerability) on the rate of major adverse cardiovascular events caused by progression of the non-culprit …

calcium
angiography
infarct
revascularisation
stemi
  • 0 views
  • 15 Feb, 2022
  • 1 location
Reverse Remodelling and Remission Markers in the Serial Evaluation of Recent-onset Dilated Cardiomyopathy

Approximately 30-40% of patients with non-ischaemic dilated cardiomyopathy (DCM) undergo significant left ventricular reverse remodelling in response to guideline-directed therapies. This is characterised by improvement in systolic dysfunction and regression of left ventricular dilatation. In some patients, extensive left ventricular reverse remodelling is accompanied by resolution of symptoms and normalisation …

heart failure
systolic dysfunction
dilated cardiomyopathy
  • 0 views
  • 21 Jul, 2021
  • 1 location
The Deep Phenotype of Lamin A/C Cardiomyopathy

This study seeks to discover clinically useful tests to improve the diagnosis of a rare and serious heart muscle disease caused by mutations in a gene called 'Lamin'. Patients born with lamin gene mutations have apparently healthy hearts initially, they begin experiencing symptoms in their twenties or thirties, and by …

  • 0 views
  • 23 Jan, 2021
  • 1 location
Cardiac ResynchrOniSation Via Stimulation of the LEFT Bundle in AF Patients.

Permanent ventricular pacing may be complicated with ventricular dyssynchrony and subsequent pacing-induced cardiomyopathy. We hypothesized that left bundle branch area pacing may prevent the development of pacing-induced cardiomyopathy in patients with permanent atrial fibrillation requiring permanent ventricular pacing. Patients with permanent atrial arrhythmia with an indication of cardiac pacing and …

  • 0 views
  • 27 Dec, 2021
  • 1 location
Heart TIMING - Heart Transplantation IMagING

The cardiac allograft rejection (CAR) and cardiac allograft vasculopathy (CAV) significantly affect the prognosis of patients after heart transplantation. The aim of the present study is to investigate and differentiate the adaptive and pathological cardiovascular changes after heart transplantation using different modalities. The investigator's main purpose is to define the …

  • 13 views
  • 02 Mar, 2022
  • 1 location
The Use of Flecainide for Treatment of Atrial Fibrillation

This prospective observational study will include patients with atrial fibrillation that has indication for treatement with flecainide. Included patients are followed during a 12 month period. During the follow-up period they will have four clinical visits, during which clinical data, advanced echocardiographic data (strain and speckle tracking) and ECGs (Glasgow …

cardioversion
electrocardiogram
antiarrhythmic drug
fibrillation
diagnostic procedure
  • 0 views
  • 12 Apr, 2022
  • 1 location
Echocardiographic Predictors of Atrial Fibrillation

This prospective study aims to identify the diagnostic accuracy of echocardiographic predictors of atrial fibrillation in patients with ESUS (embolic stroke of undetermined source) or TIA (transient ischemic attack).

electrocardiogram
stroke
transient ischemic attack
embolism
fibrillation
  • 0 views
  • 28 Sep, 2021
  • 1 location
Feasibility of Novel Clinical Trial Infrastructure, Design and Technology for Early Phase Studies in Patients With Pulmonary Hypertension (FIT-PH) (FIT-PH)

Prospective, open-label, single centre, observational study to evaluate the safety and feasibility of using pulmonary artery pressure (PAP) monitors and wearable activity monitors in patients with pulmonary hypertension (PH).

heart failure
body mass index
  • 4 views
  • 29 May, 2022
  • 1 location