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Found 42 clinical trials
Testis Needle Aspiration of Sperm in Men With Azoospermia

(TEFNA) procedure cause irreparable injury and loss of part of the testis' tubules. The hypothesis of this research is that production of sperm from the testis will be improved due to ultrasonically

  • 62 views
  • 04 Oct, 2022
  • 1 location
CMV IGG Antibodies in Semen as a Predictor for Blood Testis Barrier Damage

To assess whether the presence of Cytomegalovirus (CMV) Immunoglobulin G (IGG) antibodies in semen is a reliable predictor of male subfertility or infertility.

Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 1 location
Randomized Trial of One Stage vs Two Stage Orchidopexy for Abdominal Undescended Testis (ORCA)

This is a randomized trial designed to evaluate testicular outcomes after a single stage versus a two-stage surgical procedure to fix an undescended, one-sided testicle located in the abdomen. Also to determine and compare the costs, surgical complications and the health related quality of life for the two procedures. Testicular …

  • 0 views
  • 28 Oct, 2022
  • 1 location
Comparison of Medical Results of Testicular Sperm Extraction by Conventional Surgery and Microsurgical Track (Microsperm)

To compare motile sperm extraction rate between microTESE and conventional TESE in 18-50 years-old men with non obstructive azoospermia.

  • 32 views
  • 04 Oct, 2022
  • 1 location
Dexmedetomidine to Prevent Hepatic Ischemia-reperfusion Injury-induced Glycocalyx Degradation and Early Allograft Dysfunction in Liver Transplantation

the aim of the study is to approve the hypothesis that dexmedetomidine can protect against glycocalyx degradation induced by hepatic ischemia-reperfusion injury and hence can reduce the subsequent complications as early allograft dysfunction, other organ dysfunction and hemodynamic instability

  • 0 views
  • 04 Oct, 2022
  • 1 location
FITMI - First In Treating Male Infertility

This RCT aims to assess whether treatment with Denosumab can improve semen quality in infertile men selected by serum AMH as a positive predictive biomarker.

  • 0 views
  • 21 Mar, 2022
  • 1 location
Testis CAB: Cabazitaxel as Salvage Treatment for Cisplatin-resistant Germ Cell Cancer

Germ cell tumors belong to the most chemosensitive malignancies. Paclitaxel in combination with ifosfamide and cisplatin (TIP) has become a common regimen for salvage treatment of germ cell cancer. Cabazitaxel may overcome resistance to docetaxel and paclitaxel and might have clinical activity in patients with metastatic and progressive germ cell …

salvage treatment
neutrophil count
germ cell tumor
docetaxel
high dose chemotherapy
  • 0 views
  • 04 Oct, 2022
  • 2 locations
Short-term Testosterone Replacement in Testicular Cancer Survivors

To assess the effects of testosterone replacement therapy on fat mass and other components of the metabolic syndrome. A randomized double-blind placebo controlled intervention study, followed by an open-label treatment phase. Results of this pilot study will be used to design a multicenter randomized controlled study in a large group …

orchiectomy
carboplatin
combination chemotherapy
testosterone gel
  • 39 views
  • 04 Oct, 2022
  • 1 location
Reduced Intensity Radio-chemotherapy for Stage IIA/B Seminoma. A Multicenter, Open Label Phase II Trial With Two Cohorts

The trial investigates a stage-adapted (stage IIA or IIB) de-escalation of the standard treatments in the context of a multimodality treatment with chemo- and radiotherapy in seminoma patients. The goal is to safely de-escalate treatment while maintaining/enhancing efficacy, which is not a standard practice yet.

renal function tests
neutrophil count
orchiectomy
seminoma
carboplatin
  • 14 views
  • 12 Oct, 2022
  • 19 locations
Adjuvant Bleomycin, Etoposide and Cisplatin (BEP) Versus Carboplatin in Stage I Seminomatous Testicular Cancer (SWENOTECA-ABC)

from SWENOTECA V and VII studies indicate a high risk of relapse in patients with one or two risk factors (tumor 4 cm, stromal invasion of rete testis) treated with one course of adjuvant carboplatin

orchiectomy
neutrophil count
seminoma
bleomycin
alpha fetoprotein
  • 22 views
  • 08 Jul, 2022
  • 2 locations