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South Burlington, Vermont Clinical Trials

A listing of South Burlington, Vermont clinical trials actively recruiting patient volunteers.

RESULTS

Found (139) clinical trials

A Pivotal Study of the Premia Spine TOPS System

Degenerative spine disease is a normal part of the aging process and can cause pain and significantly limit normal movement. The most commonly diagnosed condition is Lumbar Spinal Stenosis (LSS) which presents with pain, and often weakness or numbness in the buttocks and/or lower extremities that is worsened with standing ...

Phase N/A

2.33 miles

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Efficacy and Safety Study to Evaluate Vadadustat for the Maintenance Treatment of Anemia in Subjects With Non-dialysis-dependent Chronic Kidney Disease (NDD-CKD)

This is a multicenter, randomized, open-label, active-controlled Phase 3 study of the efficacy and safety of vadadustat versus darbepoetin alfa for the maintenance treatment of anemia in subjects with NDD-CKD

Phase

2.33 miles

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Personalized CRT - PSR

The Personalized CRT study is a multi-center, single arm, prospective observational study. The purpose of the study is to better understand and characterize heart failure (HF) patient management by characterizing the use and clinical benefit of Medtronic market-released features/tools within the HF Patient Management portfolio.

Phase N/A

2.33 miles

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Safety and Efficacy of Inhaled Treprostinil in Adult PH With ILD Including CPFE

This is a multicenter, randomized (1:1 inhaled treprostinil: placebo), double-blinded, placebo-controlled trial to evaluate the safety and efficacy of inhaled treprostinil in subjects with pre-capillary pulmonary hypertension (PH) associated with interstitial lung disease (ILD) including combined pulmonary fibrosis and emphysema (CPFE). The study will include about 314 patients at approximately ...

Phase

6.59 miles

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PEEP as Rescue Therapy for Asthmatics With Elevated BMI

This study will investigate whether PEEP can prevent and/or reverse bronchoconstriction in asthmatics with a BMI > 35 kg/m2. People with late-onset non-allergic asthma that develops in the setting of obesity do not respond well to conventional asthma medications, likely because all treatments for asthma have been developed to treat ...

Phase

6.59 miles

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Two Pneumatic Compression Devices in the Treatment of Lower Extremity Lymphedema

This is a Multicentre, prospective, single (assessor) blind randomised study. The primary objective of the study is to assess volume reduction in the treatment of lymphoedematous legs with an advanced PCD compared to a simple PCD in patients with lower limb lymphoedema. The main outcome is the percentage volume reduction ...

Phase N/A

6.59 miles

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A Study of AeroVanc for the Treatment of MRSA Infection in CF Patients

This is a Phase III, randomized, multicenter, double-blind, placebo-controlled, parallel-group study to examine the safety and efficacy of AeroVanc in the treatment of persistent Methicillin resistant Staphylococcus aureus (MRSA) lung infection in patients diagnosed with cystic fibrosis (CF). After the Screening period to confirm study eligibility, subjects will be randomly ...

Phase

6.59 miles

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Increased Lung Volume as Controller Therapy for Asthma

The effect of 10 versus 0 cmH2O PEEP on airways responsiveness to inhaled methacholine will be studied using an adaptive "3+3" phase I/II study design. Dose Titration Phase (phase I): The efficacy of 8 hours of PEEP on airway responsiveness will be tested in three subjects. Efficacy will be defined ...

Phase

6.59 miles

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Trial of Roflumilast in Asthma Management (TRIM)

TRIM is a 24 week, randomized, double-masked, placebo controlled trial that will enroll 38 participants. This study will be take place in five centers of the American Lung Association- Airways Clinical Research Centers (ALA-ACRC). The centers include: Northwestern University Feinberg School of Medicine, Mount Sinai Icahn School of Medicine, Duke ...

Phase

6.59 miles

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