Reston, Virginia Clinical Trials

A listing of Reston, Virginia clinical trials actively recruiting patient volunteers.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 301 clinical trials
featured
Study of Oral Navitoclax Tablet in Combination With Oral Ruxolitinib Tablet to Assess Change in Spleen Volume in Adult Participants With Relapsed/Refractory Myelofibrosis

www.MyelofibrosisResearch.com Myelofibrosis (MF) is a bone marrow illness that affects blood-forming tissues in the body. MF disturbs the body's normal production of blood cells, causing extensive scarring in the bone marrow. This leads to severe anemia, weakness, fatigue, and an enlarged spleen. The purpose of this study is to assess …

Virginia Cancer Specialists /ID# 223016
 (8.1 away) Contact site
  • 164 views
  • 29 Apr, 2021
  • +224 other locations
featured
C2541013 MIRNA NASH  

The study aims to evaluate two, orally administered, investigational agents - PF-06865571 (DGAT2 inhibitor) and the coadministration of PF-06865571 with PF-05221304 (ACC inhibitor). This study is specifically designed to evaluate the effect of a range of doses of DGAT2i alone, and DGAT2i + ACCi, on resolution of NASH or improvement …

Gastroenterology Associates of Northern Virginia
 (6.6 away)
  • 261 views
  • 10 Jun, 2021
  • +58 other locations
featured
INCB001158 Combined With Subcutaneous (SC) Daratumumab, Compared to Daratumumab SC, in Relapsed or Refractory Multiple Myeloma

The purpose of this study is to evaluate the safety and antitumor activity of INCB001158 in combination with daratumumab SC, compared with daratumumab SC alone, in participants with relapsed or refractory multiple myeloma who have received at least 3 but not more than 5 prior lines of multiple myeloma therapy. …

daratumumab
refractory multiple myeloma
VIRGINIA CANCER SPECIALISTS-FAIRFAX
 (8.1 away) Contact site
  • 71 views
  • 28 May, 2020
  • +27 other locations
featured
ECOSPOR III: A Phase 3 Multicenter, RandomizeEd, Double Blind, Placebo COntrolled, Parallel Group Study to Evaluate the Safety, Tolerability, & Efficacy of SER-109 vs. Placebo to Reduce Recurrence of ClOstRidium Difficile Infection (CDI) in Adults

ECOSPOR III is a Phase 3, multicenter, randomized, double-blind, placebo-controlled, parallel-group study of the safety, tolerability, and efficacy of SER-109 versus placebo in adult subjects 18 years of age or older with recurrent CDI, defined as: a history of ≥ 3 CDI episodes within 9 months, inclusive of the current …

clostridium difficile
fidaxomicin
antibiotic therapy
antibiotics
vancomycin
The Gastroenterology Group, PC - Elligo Clinic Infrastructure Network
 (2.1 away) Contact site
  • 1092 views
  • 21 Dec, 2020
  • +71 other locations
featured
A Phase 2, Open-Label, Single-Arm, Multicenter Study to Evaluate the Efficacy and Safety of Pemigatinib in Participants With Previously Treated Locally Advanced/Metastatic or Surgically Unresectable Solid Tumor Malignancies Harboring Activating FGFR Mutations or Translocations (FIGHT-207)

The purpose of this study is to evaluate the efficacy and safety of pemigatinib in participants with previously treated locally advanced/metastatic or surgically unresectable solid tumor malignancies harboring activating FGFR mutations or translocations.  

primary tumor
malignancy
solid tumors
metastasis
administration intravenous
Virginia Cancer Specialists, PC
 (8.1 away) Contact site
  • 46 views
  • 14 Dec, 2020
  • +61 other locations
featured
Phase 2 Trial of MRTX849 in Combination with Pembrolizumab in Patients with Advanced Non-Small Cell Lung Cancer with KRAS G12C Mutation (KRYSTAL-7)

This Phase 2 study evaluates the clinical activity and safety of MRTX849 in combination with pembrolizumab in cohorts of patients with advanced NSCLC with KRAS G12C mutation and any PD-L1 TPS.

KRAS
pembrolizumab
Virginia Cancer Specialists - Fairfax Office
 (8.1 away) Contact site
  • 0 views
  • 10 Jun, 2021
  • +32 other locations
featured
Analysis of Wandering Patterns of Individuals with Alzheimer's

This study is looking for pairs of participants: people with dementia who have a history of wandering, and their caregivers. The study is testing a GPS device for tracking incidents of wandering.

George Mason University
 (8.2 away) Contact site
  • 0 views
  • 23 Nov, 2020
  • 1 location
featured
A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients With Advanced Solid Tumors With KRAS G12C Mutation

Evaluates the safety, tolerability, pharmacokinetics, metabolites, pharmacodynamics, and clinical activity of MRTX849 in patients with advanced solid tumors with a KRAS G12C mutation. MRTX849 is an orally-available small molecule inhibitor of KRAS G12C.

malignant solid tumor
advanced solid tumor
solid tumor
Mirati Research Site
 (8.1 away) Contact site
  • 405 views
  • 08 Mar, 2021
  • +66 other locations
featured
A Phase 2 Study of Sitravatinib in Combination with Nivolumab in Patients with Advanced or Metastatic Urothelial Carcinoma (516-003)

This is a study involving an investigational (experimental) drug called sitravatinib, given in combination with the immunotherapy nivolumab (also known as OPDIVO®).  Sitravatinib is designed to block specific proteins that are thought to cause tumors to grow and to prevent growth of new blood vessels that help cancer tumors to …

urothelial carcinoma
platinum-based chemotherapy
advanced urothelial carcinoma
tumor cells
cancer
Virginia Cancer Specialists- Fairfax
 (8.1 away) Contact site
  • 80 views
  • 02 Jun, 2021
  • +35 other locations
featured
An Open-Label Phase 1/2 Study of INCB039110 in Combination With Osimertinib in Subjects With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

An Open-Label Phase 1/2 Study of INCB039110 in Combination With Osimertinib in Subjects With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

KIT
advanced lung cancer
tyrosine
lung carcinoma
systemic therapy
Incyte Corporation
 (8.2 away) Contact site
  • 358 views
  • 08 Dec, 2020
  • +3 other locations