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Charlottesville, Virginia Clinical Trials

A listing of Charlottesville, Virginia clinical trials actively recruiting patient volunteers.

RESULTS

Found (460) clinical trials

Phase I/II Trial of a Long Peptide Vaccine (LPV7) Plus TLR Agonists

The purpose of this study is to learn what effects (good and bad) an experimental vaccine (LPV7) plus tetanus peptide and other substances called polyICLC, resiquimod, and Montanide ISA-51 have on you and your melanoma. We will also look at whether the experimental vaccine and these drugs cause any changes ...

Phase

5.55 miles

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Best Endovascular vs. Best Surgical Therapy in Patients With Critical Limb Ischemia

Male and female subjects aged 18 years or older will be randomized to receive either open surgical treatment or endovascular treatment. They will be followed for at least 2 years and up to 4 years and 2 months after treatment to primarily assess survival and major adverse limb events in ...

Phase N/A

5.55 miles

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Follow-up of AKI in Neonates During Childhood Years

The purpose of this study is to learn more about how to identify signs of early chronic kidney diseases in children who were born prematurely with low birth weight (less than 3 pounds). Researchers plan to compare the kidney function in children who experienced acute kidney injury (AKI) in the ...

Phase N/A

5.55 miles

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Standard or Comprehensive Radiation Therapy in Treating Patients With Early-Stage Breast Cancer Previously Treated With Chemotherapy and Surgery

PRIMARY OBJECTIVES: To evaluate whether the addition of chest wall + regional nodal radiation therapy (XRT) after mastectomy or breast + regional nodal XRT after breast conserving surgery will significantly reduce the rate of events for invasive breast cancer recurrence-free interval (IBC-RFI) in patients who present with histologically positive axillary ...

Phase N/A

5.55 miles

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Lung Cancer Information Study (LCIS-R01)

Appropriate utilization of treatment with systemic therapy remains problematic in advanced lung cancer. A major issue continues to be over-treatment. Contributors to this include barriers in communication concerning patients' wishes and goals, lack of formal monitoring of symptoms using validated health-related quality of life (QL) and patient reported outcomes (PROs) ...

Phase N/A

5.55 miles

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Minimizing the Utilization of Voiding Cystourethrography for Patients With Antenatal Hydronephrosis

Investigators conducted a previous retrospective study to evaluate other possible findings on ultrasound that may better predict reflux. Investigators found that if a postnatal ultrasound showed any of the three findings of hydroureter, duplication or dysmorphic kidney, then the odds ratio of detecting reflux was 8.07 (95%CI 3.86, 16.87). The ...

Phase N/A

5.55 miles

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Accuro Versus Traditional Landmark Palpation Technique to Determine Accurate Spinal Level for Procedures

Patients who are undergoing any interventional pain procedure under fluoroscopy at the UVA Pain Management Clinic will be approached for consent. Each participant will sit up on the edge of the bed in the pre-procedural area of fluoroscopy. For each participant, a provider will first attempt to identify the L4/L5 ...

Phase N/A

5.55 miles

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Assessment of the Changes in Cortical and Medullary Renal Blood Flow During Exercise in Healthy Subjects Using Contrast Enhanced Ultrasound

This study requires a screening day and two visits on separate days to the Clinical Research Unit (CRU). Three visits total. Screening Visit: The subjects will undergo detailed history and physical examination. The inclusion and exclusion criteria will be reviewed. The details of the study procedures, potential risks and benefits ...

Phase

5.55 miles

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Hyperandrogenemia and Altered Day-night LH Pulse Patterns

This is a randomized, placebo-controlled, double-blinded crossover study to test the following hypothesis: In mid- to late pubertal girls with hyperandrogenism (HA), acute progesterone suppression of waking LH pulse frequency is greater after 2 weeks of spironolactone pretreatment compared to after 2 weeks of placebo pretreatment. We will only study ...

Phase N/A

5.55 miles

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Handheld 3D Lumbar Spine Navigation: A Clinical Validation Study RM002

Currently, at UVA, handheld ultrasound devices (like those used to view an unborn baby) are only two dimensional. The Accuro is a three dimensional handheld ultrasound device. This device uses sound waves to create pictures of the spine in three dimensions. This may allow the physician to view the spine ...

Phase N/A

5.55 miles

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