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Charlottesville, Virginia Clinical Trials

A listing of Charlottesville, Virginia clinical trials actively recruiting patient volunteers.

RESULTS

Found (24) clinical trials

Relative Desirability of Metformin vs. Birth Control Pill in Treating PCOS in Women of Later Reproductive Age

This is a randomized, controlled, double-blinded, crossover study. The investigators will recruit women with PCOS in ages 40-47 yo. Subjects will be randomized to either receive metformin (2000 mg daily) or low dose oral contraceptives (OCs: 20 mcg ethinyl estradiol/norethindrone acetate 1mg) for a total of 6 months, and they ...

Phase N/A

0.0 miles

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Microcirculatory and Tissue and Cerebral Oxygenation in Preeclampsia and Normal Pregnancy: An Observation Study

Study procedures: Consented at the time of enrollment in the study, which will be at hospital admission for delivery. Demographic data, medical history, obstetrical history, prenatal history and delivery information will be obtained from medical records and the subject Proteinuria, Placental weight, BMI, Birth weight and gender, mother smoker or ...

Phase N/A

5.55 miles

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Urinary DENND1A.V2 as a Predictor of Pubertal Hyperandrogenemia

To date, the mechanisms underlying excess androgen production from steroid producing tissues have been unclear, but recent Genome Wide Association Studies (GWAS) have provided additional data in this regard. Initial GWAS data in a Han Chinese population identified some 12 loci as potential PCOS susceptibility gene candidates. One of these ...

Phase N/A

5.55 miles

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Hyperandrogenemia and Altered Day-night LH Pulse Patterns

This is a randomized, placebo-controlled, double-blinded crossover study to test the following hypothesis: In mid- to late pubertal girls with hyperandrogenism (HA), acute progesterone suppression of waking LH pulse frequency is greater after 2 weeks of spironolactone pretreatment compared to after 2 weeks of placebo pretreatment. We will only study ...

Phase N/A

5.55 miles

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Handheld 3D Lumbar Spine Navigation: A Clinical Validation Study RM002

Currently, at UVA, handheld ultrasound devices (like those used to view an unborn baby) are only two dimensional. The Accuro is a three dimensional handheld ultrasound device. This device uses sound waves to create pictures of the spine in three dimensions. This may allow the physician to view the spine ...

Phase N/A

5.55 miles

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Data and Specimen Bank of Patients Diagnosed With and at High-risk for Gynecologic Cancers

The purpose of this project is to establish a bank at UVa of tampon samples, cervical swabs, blood, associated tumor specimens that would otherwise be discarded, and relevant medical data from consenting patients that have suspected and/or confirmed gynecological cancer diagnoses. The specimens collected will be saved for analysis on ...

Phase N/A

5.55 miles

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Immune Effects in Patients Treated With Whole Breast Irradiation

The purpose of this study is to obtain data to determine whether whole breast irradiation (WBI) differentially influences the frequency of components of innate and adaptive immunity and their relative functional activity, to assess the patient's quality of life (QOL) and to evaluate the cosmetic assessment of the breast on ...

Phase N/A

5.55 miles

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Effect of Spironolactone on Adrenal or Ovarian Androgen Production in Overweight Pubertal Girls With Androgen Excess

This study will test whether spironolactone administration can ameliorate androgen (male hormone) overproduction in overweight pubertal girls with androgen excess. The investigators hypothesize that reduction in P450c17alpha overactivity and androgen receptor blockade by 12 weeks of spironolactone administration will improve androgen levels after adrenal stimulation testing with adrenocorticotropic hormone (ACTH) ...

Phase N/A

5.55 miles

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Palpation and ACCURO for Placing Spinal in C-section

The Accuro is a three dimensional handheld ultrasound device. This device uses sound waves to create pictures of the spine in three dimensions. This may allow the physician to view the spine in more detail for procedures such as spinal anesthesia and other diagnostic procedures. We aim to assess the ...

Phase N/A

5.55 miles

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Dermacell ADM Without Basement Membrane

DermACELL acellular dermal matrix (D-ADM) is the trade name of LifeNet Health's acellular dermal matrix (ADM). LifeNet Health will remove the basement membrane from the D-ADM and this product will be compared to FlexHD Pliable, which does not include a basement membrane in order to demonstrate that D-ADM without a ...

Phase N/A

5.55 miles

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