Fort Worth, Texas Clinical Trials

A listing of Fort Worth, Texas clinical trials actively recruiting patient volunteers.

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Found 269 clinical trials
Ecopipam Tablets to Study Tourette Syndrome in Children and Adolescents - Open Label Extension

This study is an international, multicenter, open-label, long term extension study evaluating the safety of ecopipam tablets for the treatment of children and adolescent subjects with Tourette Syndrome.

North Texas Clinical Trials
 (2.3 away) Contact site
  • 15 views
  • 29 Apr, 2021
  • +76 other locations
A Study of Rituximab-Gemcitabine-Dexamethasone-Platinum (R-GDP) With or Without Selinexor in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma

The purpose of this Phase 2/3 study is to evaluate efficacy and safety of the combination of selinexor and R-GDP (SR-GDP) in patients with RR DLBCL who are not intended to receive hematopoetic stem cell transplantation (HSCT) or chimeric antigen receptor T cell (CAR-T) therapy. The Phase 2 portion of …

Texas Oncology - Fort Worth
 (2.2 away) Contact site
  • 37 views
  • 16 Mar, 2021
  • +68 other locations
Phase 4 Study of Obeticholic Acid Evaluating Clinical Outcomes in Patients With Primary Biliary Cholangitis

Primary Biliary Cholangitis (PBC) is a serious, life-threatening, bile acid related liver disease of unknown cause. Without treatment, it frequently progresses to liver fibrosis and eventual cirrhosis requiring liver transplantation or resulting in death. The investigational drug, Obeticholic Acid (OCA) is a modified bile acid and FXR agonist that is …

immune globulin
bile acid
glutaric acid
ursodiol
chenodeoxycholic acid
Baylor All Saints Medical Center
 (2.2 away) Contact site
  • 402 views
  • 09 May, 2021
  • +322 other locations
Dociparstat for the Treatment of Severe COVID-19 in Adults at High Risk of Respiratory Failure

A randomized, double-blind, placebo-controlled Phase 2/3 study to evaluate the safety and efficacy of DSTAT in patients with Acute Lung Injury (ALI) due to COVID-19. This study is designed to determine if DSTAT can accelerate recovery and prevent progression to mechanical ventilation in patients severely affected by COVID-19.

respiratory failure
oximetry
lung injury
SARS
acute lung injury
Texas Health Harris Methodist Hospital Fort Worth
 (1.9 away) Contact site
  • 64 views
  • 24 Feb, 2021
  • +11 other locations
Amplatzer Amulet LAAO vs. NOAC

The objective of this trial is to evaluate the safety and effectiveness of the Amulet LAA occluder compared to NOAC therapy in patients with non-valvular AF at increased risk for ischemic stroke and who are recommended for long-term NOAC therapy. The clinical investigation is a prospective, randomized, multicenter active control …

embolism
ischemic stroke
left atrial appendage occlusion
electrocardiogram
vascular disease
Baylor All Saints Medical Center at Fort Worth
 (2.3 away) Contact site
  • 7 views
  • 29 Apr, 2021
  • +54 other locations
Study of a Pneumococcal Conjugate Vaccine When Administered Concomitantly With Routine Pediatric Vaccines in Healthy Toddlers and Infants

Primary Objective: To assess the safety profile of each SP0202 formulation and Prevnar 13 in toddlers and infants (after each and any injection). To assess the immune response (serotype specific IgG concentration) of the SP0202 formulations and Prevnar 13 1 month after the administration of one dose in toddlers (Groups …

Investigational Site Number 8400015
 (2.3 away) Contact site
  • 27 views
  • 30 Apr, 2021
  • +34 other locations
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer ALCHEMIST Chemo-IO Study

This phase III ALCHEMIST trial compares the addition of pembrolizumab to usual chemotherapy versus usual chemotherapy for the treatment of stage IB, II, or IIIA non-small cell lung cancer that has been removed by surgery. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the …

carcinoma
neutrophil count
platelet count
pemetrexed
paclitaxel
UT Southwestern/Simmons Cancer Center-Fort Worth
 (2.3 away) Contact site
  • 136 views
  • 09 May, 2021
  • +782 other locations
A Study of Mirikizumab (LY3074828) in Participants With Crohn's Disease

The reason for this study is to see if the study drug mirikizumab is safe and effective in participants with moderately to severely active Crohn's disease.

ustekinumab
crohn's disease
Cook Children's Hospital
 (2.3 away) Contact site
  • 646 views
  • 09 May, 2021
  • +965 other locations
A Study of LY3295668 Erbumine in Participants With Relapsed/Refractory Neuroblastoma

The reason for this study is to see if the study drug LY3295668 erbumine is safe in participants with relapsed/refractory neuroblastoma.

cyclophosphamide
refractory neuroblastoma
topotecan
bone marrow procedure
Cook Children's Hospital
 (2.3 away) Contact site
  • 7 views
  • 09 May, 2021
  • +45 other locations
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

hemoglobin a1c
cardiovascular disease
body mass index
North Hills Medical Research
 (7.9 away) Contact site
  • 593 views
  • 09 May, 2021
  • +858 other locations