Pawtucket, Rhode Island Clinical Trials

A listing of Pawtucket, Rhode Island clinical trials actively recruiting patient volunteers.

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Found 45 clinical trials
Study to Assess the Efficacy and Safety of LYS006 in Patients With Moderate to Severe Inflammatory Acne

The main purpose of this study is to assess preliminary efficacy and safety of LYS006 in patients with moderate to severe inflammatory acne and to determine if LYS006 has an adequate clinical profile for further clinical development.

Novartis Investigative Site
 (7.0 away) Contact site
  • 16 Jun, 2021
  • +24 other locations
Emergency Department-Initiated Buprenorphine Validation Network Trial

This study will (1) recruit, train and provide resources to approximately 30 Emergency Department (ED) sites throughout the U.S. using implementation facilitation strategies to provide ED-initiated buprenorphine (BUP) for patients presenting with opioid use disorder (OUD) who are not receiving medications for opioid use disorder (MOUD). Once implementation is adequately …

Rhode Island Hospital
 (4.0 away) Contact site
  • 16 Apr, 2021
  • +36 other locations
Thymalfasin (Thymosin Alpha 1) to Treat COVID-19 Infection

It is our hypothesis that a course of Ta1 administered to hospitalized individuals with COVID-19 infection and lymphocytopenia will improve the time to recovery (primary objective) and severity of infection (secondary objectives) compared to untreated individuals in the same hospital with comparable lymphocytopenia. After screening, hospitalized patients with COVID-19 and …

The Miriam Hospital
 (2.3 away) Contact site
  • 25 Jan, 2021
  • 1 location
Effects of DHEA in Pulmonary Hypertension

The goal of this crossover trial is to determine whether the study drug dehydroepiandrosterone (DHEA) improves right ventricular longitudinal strain measured by cardiac magnetic resonance imaging at 18 weeks compared to placebo and to assess side effects and safety in pulmonary arterial hypertension.

pulmonary disease
ventilation perfusion lung scan
forced expiratory volume
pulmonary function test
Rhode Island Hospital Pulmonary Hypertension Center
 (4.0 away) Contact site
  • 26 Jan, 2021
  • 1 location
Safety and Efficacy of Nyxol With Pilocarpine Eye Drops in Subjects With Presbyopia

The objectives of this study are: To evaluate the efficacy of Nyxol + Pilocarpine to improve DCNVA in subjects with presbyopia

West Bay Eye
 (8.7 away) Contact site
  • 27 Apr, 2021
  • +35 other locations
Pulmonary Hypertension and Anastrozole Trial

The primary objectives of this study are to determine whether the study drug, anastrozole may improve six minute walk distance at six months compared to placebo and to assess safety and side effects up to twelve months in pulmonary arterial hypertension (PAH).

left ventricular end-diastolic pressure
connective tissue disease
pulmonary disease
heart disease
Rhode Island Hospital
 (4.1 away) Contact site
  • 25 Jan, 2021
  • +6 other locations
Ribociclib and Letrozole Treatment in Ovarian Cancer

The study evaluates the response to treatment with Ribociclib and Letrozole in patients with low grade serous cancer of the ovary, fallopian tube or peritoneum.

Women & Infants Hospital
 (5.9 away) Contact site
  • 03 Feb, 2021
  • +25 other locations
A Study of CIN-107 in Adults With Treatment-Resistant Hypertension (rHTN)

This is a randomized, double-blind, placebo-controlled, dose-ranging Phase 2 study to evaluate the efficacy and safety of CIN-107 as compared to placebo after 12 weeks of treatment in patients with treatment-resistant hypertension (rHTN).

medication regimen
antihypertensive drugs
CinCor Site 63
 (3.3 away) Contact site
  • 13 Jun, 2021
  • +77 other locations
Study With Afuresertib and Paclitaxel in Platinum Resistant Ovarian

Afuresertib is an AKT inhibitor, a new class of agents under development that may provide physicians with a new clinical option to control platinum resistant ovarian cancer (PROC) progression. Afuresertib plus chemotherapy has demonstrated anti-tumor efficacy and an acceptable safety profile in patients with PROC in a published Phase I/II …

Women & Infants Hospital of Rhode Island
 (3.5 away) Contact site
  • 07 Mar, 2021
  • +24 other locations
A Study of JNJ-63733657 in Participants With Early Alzheimer's Disease

The primary purpose of this study is to evaluate the effect of JNJ-63733657 versus placebo on cognitive decline using the Alzheimer's Disease Assessment Scale Cognitive subscale 13-item version (ADAS-Cog13).

alzheimer's disease
cognitive assessment
cognitive decline
Brown University School of Medicine
 (2.3 away) Contact site
  • 03 Jun, 2021
  • +141 other locations