Lincoln, Rhode Island Clinical Trials

A listing of Lincoln, Rhode Island clinical trials actively recruiting patient volunteers.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 396 clinical trials
An Efficacy and Safety Study of Nemolizumab (CD14152) in Participants With Prurigo Nodularis

The primary objective is to assess the efficacy of nemolizumab (CD14152) compared to placebo in participants greater than or equal to (>=) 18 years of age with prurigo nodularis (PN) after a 16 week treatment period.

Galderma Investigational Site
 (6.5 away) Contact site
  • 0 views
  • 19 Sep, 2021
  • +87 other locations
PRISM Study-Pruritus Relief Through Itch Scratch Modulation

To investigate the anti-pruritic efficacy and safety of Nalbuphine ER (NAL ER) tablets in Prurigo Nodularis. Subjects will be randomized to NAL ER (or matching placebo) with the primary endpoint evaluation at Week 14. During the open label extension, subjects who received NAL ER will continue on NAL ER and …

nalbuphine
Study Site 131
 (6.9 away) Contact site
  • 671 views
  • 21 Aug, 2021
  • +85 other locations
Multi-arm Optimization of Stroke Thrombolysis

The primary efficacy objective of the MOST trial is to determine if argatroban (100g/kg bolus followed by 3g/kg per minute for 12 hours) or eptifibatide (135g/kg bolus followed by 0.75g/kg/min infusion for two hours) results in improved 90-day modified Rankin scores (mRS) as compared with placebo in acute ischemic stroke …

Rhode Island Hospital
 (6.5 away) Contact site
  • 121 views
  • 11 Aug, 2021
  • +94 other locations
Long Term Extension Study of the Safety and Efficacy of AVP-786 for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type

This is an extension study of the Phase 3 Studies 15-AVP-786-301, 15-AVP-786-302, and 17-AVP-786-305, which also allows participants from the Phase 2 Study 12-AVR-131 to be included.

Rhode Island Mood & Memory Research Institute
 (7.3 away) Contact site
  • 30 views
  • 04 Sep, 2021
  • +296 other locations
A Study of Sotatercept for the Treatment of Pulmonary Arterial Hypertension (STELLAR)

The objectives of this study are to evaluate the efficacy and safety of sotatercept treatment (plus background PAH therapy) versus placebo (plus background PAH therapy) at 24 weeks in adults with PAH.

Rhode Island Hospital
 (6.5 away) Contact site
  • 0 views
  • 19 Sep, 2021
  • +63 other locations
Filgrastim-Mobilized Stem Cells for Transplantation Using Unrelated Donors

The purpose of the study is to: Establish and evaluate a system for collection of filgrastim-mobilized peripheral blood stem cells from National Marrow Donor Program donors (NMDP) donors Assess the safety among NMDP donors of filgrastim administration and PBSC leukapheresis Assess the safety and efficacy of filgrastim-mobilized PBSC in unrelated …

Rhode Island Blood Center
 (4.9 away) Contact site
  • 2808 views
  • 21 Mar, 2021
  • +62 other locations
Project MIMIC (Maximizing Implementation of Motivational Incentives in Clinics)

There is an urgent need for effective treatments for patients with opioid use disorder (OUD). This study will train opioid treatment centers in an evidence-based behavioral treatment called contingency management (CM). Contingency management (i.e., motivational incentives for achieving pre-defined treatment goals) is one of the only behavioral interventions shown to …

The Journey to Hope, Health, and Healing
 (7.8 away) Contact site
  • 22 views
  • 24 Jan, 2021
  • +9 other locations
A Study of ASP1948 Targeting an Immune Modulatory Receptor as a Single Agent and in Combination With a PD-l Inhibitor (Nivolumab or Pembrolizumab) in Subjects With Advanced Solid Tumors

The purpose of this study is to evaluate the tolerability and safety profile of ASP1948 when administered as a single agent and in combination with nivolumab or pembrolizumab in participants with locally advanced (unresectable) or metastatic solid tumors; characterize the pharmacokinetic profile of ASP1948 when administered as a single agent …

Women And Infants
 (8.6 away) Contact site
  • 134 views
  • 08 Sep, 2021
  • +68 other locations
Moderately Preterm Infants With Caffeine at Home for Apnea (MoCHA) Trial

The objective of this study is to evaluate the effect of continuing treatment with caffeine citrate in the hospital and at home in moderately preterm infants with resolved apnea of prematurity on days of hospitalization after randomization.

Brown University, Women & Infants Hospital of Rhode Island
 (8.6 away) Contact site
  • 23 views
  • 16 Sep, 2021
  • +17 other locations
Durvalumab Treatment in Combination With Chemotherapy and Bevacizumab Followed by Maintenance Durvalumab Bevacizumab and Olaparib Treatment in Advanced Ovarian Cancer Patients

This is a Phase III randomised, double-blind, multi-centre study to evaluate the efficacy and safety of durvalumab in combination with standard of care platinum based chemotherapy and bevacizumab followed by maintenance durvalumab and bevacizumab or durvalumab, bevacizumab and olaparib in patients with newly diagnosed advanced ovarian cancer.

Research Site
 (4.9 away) Contact site
  • 84 views
  • 19 Sep, 2021
  • +293 other locations