Cranston, Rhode Island Clinical Trials

A listing of Cranston, Rhode Island clinical trials actively recruiting patient volunteers.

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Found 118 clinical trials
A Long-term Study to Evaluate Safety and Maintenance of Treatment Effect of LY3074828 in Participants With Moderate-to-Severe Plaque Psoriasis (OASIS-3)

The purpose of this study is to evaluate the long-term safety and maintenance of efficacy of mirikizumab in participants with moderate-to-severe plaque psoriasis.

mirikizumab
plaque psoriasis
Clinical Partners LLC
 (5.2 away) Contact site
  • 727 views
  • 26 Sep, 2021
  • +361 other locations
A Study to Evaluate the Effect of Testosterone Replacement Therapy (TRT) on the Incidence of Major Adverse Cardiovascular Events (MACE) and Efficacy Measures in Hypogonadal Men

This is a blinded and placebo-controlled study of topical testosterone replacement therapy (TRT) in symptomatic hypogonadal men with increased risk for cardiovascular (CV) disease.

testosterone level
serum testosterone
replacement therapy
testosterone topical
testosterone
Ocean State Clin Rese Part,LLC /ID# 170547
 (9.2 away) Contact site
  • 16902 views
  • 26 Sep, 2021
  • +495 other locations
Efficacy and Safety Study of Tisotumab Vedotin for Patients With Solid Tumors

This trial will study tisotumab vedotin to find out whether it is an effective treatment for certain solid tumors and what side effects (unwanted effects) may occur. There are three parts to this study. In Part A, the treatment will be given to participants every 3 weeks (3-week cycles). In …

tyrosine
systemic therapy
kinase inhibitor
cancer
adenocarcinoma
Rhode Island Hospital
 (3.1 away) Contact site
  • 226 views
  • 16 Sep, 2021
  • +48 other locations
Maintenance With Selinexor/Placebo After Combination Chemotherapy in Participants With Endometrial Cancer [SIENDO]

This is a prospective, multicenter, double-blind, placebo-controlled, randomized Phase 3 study. The purpose of the study is to obtain evidence of efficacy for maintenance selinexor in participants with advanced or recurrent endometrial cancer. Participants with primary stage IV or recurrent disease who are in partial or complete response after having …

uterine disease
recurrent disease
liver metastasis
carcinosarcoma
cancer
Women & Infants Hospital of Rhode Island
 (3.5 away) Contact site
  • 47 views
  • 26 Sep, 2021
  • +107 other locations
A Study With ABBV-155 Alone and in Combination With Taxane Therapy in Adults With Relapsed and/or Refractory Solid Tumors

An open-label, dose-escalation (Part 1), dose-expansion (Part 2) study to assess the safety, pharmacokinetics (PK), and preliminary efficacy of ABBV-155 alone and in combination with paclitaxel or docetaxel. In Part 1 (dose escalation), participants will receive escalating doses of ABBV-155 monotherapy (Part 1a) or ABBV-155 in combination with paclitaxel or …

Lifespan Cancer Institute /ID# 204256
 (3.1 away) Contact site
  • 542 views
  • 18 Sep, 2021
  • +46 other locations
A Study of Apalutamide in Participants With High-Risk Localized or Locally Advanced Prostate Cancer Who Are Candidates for Radical Prostatectomy

The purpose of this study is to determine if treatment with apalutamide plus androgen deprivation therapy (ADT) before and after radical prostatectomy (RP) with pelvic lymph node dissection (pLND) in participants with high-risk localized or locally advanced prostate cancer results in an improvement in pathological complete response (pCR) rate and …

antiandrogen therapy
cancer
adenocarcinoma
prostatectomy
metastasis
Omega Medical Research
 (5.2 away) Contact site
  • 318 views
  • 26 Sep, 2021
  • +358 other locations
Effect of Evolocumab in Patients at High Cardiovascular Risk Without Prior Myocardial Infarction or Stroke

This study will assess the effect of lowering low-density lipoprotein cholesterol (LDL-C) with evolocumab on major cardiovascular events in adults without a prior myocardial infarction (MI) or stroke who are at high risk of a cardiovascular event.

stroke
arterial disease
infarct
myocardial infarction
diabetes
Miriam Hospital
 (3.1 away) Contact site
  • 542 views
  • 26 Sep, 2021
  • +1336 other locations
Evaluation of Efficacy and Safety of Pamrevlumab in Patients With Idiopathic Pulmonary Fibrosis

This is a Phase 3 trial to evaluate the efficacy and safety of 30 mg/kg intravenous (IV) infusions of pamrevlumab administered every 3 weeks as compared to placebo in subjects with Idiopathic Pulmonary Fibrosis

carbon monoxide
nintedanib
diffusion capacity of the lung for carbon monoxide
idiopathic pulmonary fibrosis
pirfenidone
Research Center
 (3.1 away) Contact site
  • 349 views
  • 23 Sep, 2021
  • +227 other locations
A Maintenance Study of Mirikizumab in Participants With Moderately to Severely Active Ulcerative Colitis

The purpose of this study is to evaluate the efficacy and safety of mirikizumab as maintenance therapy in participants who completed prior 12-week induction study AMAN (NCT03518086).

mirikizumab
endoscopy
Ocean State Clinical Research Partners
 (9.2 away) Contact site
  • 386 views
  • 27 Sep, 2021
  • +913 other locations
A Study to Evaluate the Efficacy and Safety of Bimekizumab in Study Participants With Moderate to Severe Hidradenitis Suppurativa

The purpose of the study is to evaluate the efficacy and safety of bimekizumab in study participants with moderate to severe hidradenitis suppurativa (HS)

hidradenitis
abscess
bimekizumab
antibiotics
Hs0003 50180
 (3.1 away) Contact site
  • 303 views
  • 26 Sep, 2021
  • +94 other locations