Cranston, Rhode Island Clinical Trials

A listing of Cranston, Rhode Island clinical trials actively recruiting patient volunteers.

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Found 105 clinical trials
A Long-term Study to Evaluate Safety and Maintenance of Treatment Effect of LY3074828 in Participants With Moderate-to-Severe Plaque Psoriasis (OASIS-3)

The purpose of this study is to evaluate the long-term safety and maintenance of efficacy of mirikizumab in participants with moderate-to-severe plaque psoriasis.

mirikizumab
plaque psoriasis
Clinical Partners LLC
 (5.2 away) Contact site
  • 717 views
  • 12 Sep, 2021
  • +361 other locations
A Study of Apalutamide in Participants With High-Risk Localized or Locally Advanced Prostate Cancer Who Are Candidates for Radical Prostatectomy

The purpose of this study is to determine if treatment with apalutamide plus androgen deprivation therapy (ADT) before and after radical prostatectomy (RP) with pelvic lymph node dissection (pLND) in participants with high-risk localized or locally advanced prostate cancer results in an improvement in pathological complete response (pCR) rate and …

cancer
prostatectomy
androgens
androgen suppression
antiandrogen therapy
Omega Medical Research
 (5.2 away) Contact site
  • 318 views
  • 19 Sep, 2021
  • +356 other locations
Effect of Evolocumab in Patients at High Cardiovascular Risk Without Prior Myocardial Infarction or Stroke

This study will assess the effect of lowering low-density lipoprotein cholesterol (LDL-C) with evolocumab on major cardiovascular events in adults without a prior myocardial infarction (MI) or stroke who are at high risk of a cardiovascular event.

arterial disease
diabetes
stroke
infarct
myocardial infarction
Miriam Hospital
 (3.1 away) Contact site
  • 542 views
  • 19 Sep, 2021
  • +1332 other locations
Efficacy and Safety of Gefapixant (MK-7264) in Women With Chronic Cough and Stress Urinary Incontinence (MK-7264-042)

The purpose of this study is to evaluate the efficacy and safety of gefapixant, in improving symptoms of cough-induced stress urinary incontinence (SUI) in adult female participants with refractory or unexplained chronic cough. The primary hypothesis is that gefapixant is superior to placebo in reducing the frequency of cough-induced SUI …

chest radiograph
gefapixant
refractory chronic cough
unexplained chronic cough
AAPRI Clinical Research Institute ( Site 0031)
 (5.2 away) Contact site
  • 88 views
  • 19 Sep, 2021
  • +89 other locations
Metabolic Interventions to Resolve Non-alcoholic Steatohepatitis (NASH) With Fibrosis (MIRNA)

The study aims to evaluate two, orally administered, investigational agents - PF-06865571 (DGAT2 inhibitor) and the coadministration of PF-06865571 with PF-05221304 (ACC inhibitor). This study is specifically designed to evaluate the effect of a range of doses of DGAT2i alone, and DGAT2i + ACCi, on resolution of NASH or improvement …

hepatic fibrosis
fibrosis
steatohepatitis
University Gastroenterology
 (2.4 away) Contact site
  • 72 views
  • 08 Sep, 2021
  • +350 other locations
A Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With Migraine

The reason for this study is to see if lasmiditan is safe and effective in children aged 6 to 17 with migraine. The study will last up to 20 weeks and may include up to 4 visits.

preventive medication
lasmiditan
ly573144
headache
Omega Medical Research
 (5.2 away) Contact site
  • 130 views
  • 11 Sep, 2021
  • +242 other locations
A Study of Trastuzumab Deruxtecan (T-DXd) Versus Trastuzumab Emtansine (T-DM1) in High-risk HER2-positive Participants With Residual Invasive Breast Cancer Following Neoadjuvant Therapy (DESTINY-Breast05)

Patients with HER2-positive primary breast cancer (BC) who do not achieve complete response after appropriate neoadjuvant therapy are at higher risk of disease recurrence. More effective treatment options are needed for this patient population. This study will examine the efficacy and safety of trastuzumab deruxtecan (T-DXd) compared with trastuzumab emtansine …

Women & Infants Hospital of RI
 (2.4 away) Contact site
  • 1 views
  • 10 Sep, 2021
  • +425 other locations
A Study to Evaluate the Safety and Efficacy of AZD5718 in Participants With Proteinuric Chronic Kidney Disease

The purpose of the study is to evaluate the dose-response efficacy, safety, and pharmacokinetics (PK) of AZD5718 in participants with proteinuric chronic kidney disease.

angiotensin
diuretics
aldosterone
nephropathy
antihypertensive drugs
Research Site
 (4.7 away) Contact site
  • 0 views
  • 19 Sep, 2021
  • +103 other locations
A Phase 3 Study to Evaluate the Efficacy and Safety of CTP-543 in Adult Patients With Moderate to Severe Alopecia Areata (THRIVE-AA1)

This is a multi-center Phase 3 study to evaluate the safety and effectiveness of an investigational study drug (called CTP-543) in adults (18 years and older) who have 50% or greater scalp hair loss. The study is placebo-controlled, meaning that some patients entering the study will not receive active study …

areata alopecia
Brown Dermatology, Inc. Department of Dermatology The Warren Alpert Medical School
 (3.1 away) Contact site
  • 33 views
  • 19 Sep, 2021
  • +77 other locations
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)

The reason for this study is to see how safe and effective the study drug donanemab is in participants with early Alzheimer's disease. Additional participants will be enrolled to an addendum safety cohort. The participants will be administered open-label donanemab.

mini-mental state examination
positron emission tomography
flortaucipir
alzheimer's disease
florbetapir
Rhode Island Hospital
 (3.1 away) Contact site
  • 89 views
  • 17 Sep, 2021
  • +394 other locations