Monroeville, Pennsylvania Clinical Trials

A listing of Monroeville, Pennsylvania clinical trials actively recruiting patient volunteers.

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Found 11 clinical trials
Safety and Efficacy Study to Compare Smoflipid and Intralipid 20% in Pediatric Patients of 3 Months to 16 Years of Age

Evaluate the safety and efficacy of Smoflipid compared to standard of care lipid emulsion Intralipid 20% administered via a central vein in pediatric patients 3 months to 16 years of age who require parenteral nutrition for at least 90 days and up to 1 year.

Children's Hospital of Pittsburgh of UPMC
 (9.9 away) Contact site
  • 1 views
  • 13 Mar, 2021
  • 1 location
Mobile Devices to Detect Early Pneumonitis in Stage III NSCLC Patients on Durvalumab.

A study of whether mobile devices can improve the detection of pulmonary AEs (including pneumonitis) in stage III NSCLC patients post-CRT, while on durvalumab.

Research Site
 (9.9 away) Contact site
  • 12 views
  • 25 May, 2021
  • +34 other locations
Study of Glycerol Phenylbutyrate & Sodium Phenylbutyrate in Phenylbutyrate Na ve Patients With Urea Cycle Disorders

This is a randomized, controlled, open-label parallel arm study to assess the safety, tolerability, pharmacokinetics and ammonia control, of RAVICTI as compared to NaPBA in urea cycle disorder subjects not currently or previously chronically treated with phenylacetic acid (phenylacetate; PAA) prodrugs. The study design will include: 1) Baseline Period; 2) …

hysterectomy
genetic testing
ravicti
phenylacetic acid
deficiency
Children's Hospital of Pittsburgh of UPMC
 (9.9 away) Contact site
  • 43 views
  • 01 Feb, 2021
  • +15 other locations
Apixaban for the Acute Treatment of Venous Thromboembolism in Children

To assess the safety and descriptive efficacy of apixaban in pediatric subjects requiring anticoagulation for the treatment of a VTE.

heparin
venous thromboembolism
apixaban
vitamin k antagonist
vitamin k
UPMC Children's Hospital of Pittsburgh
 (9.9 away) Contact site
  • 0 views
  • 31 May, 2021
  • +169 other locations
Efficacy Safety and Pharmacokinetics of Sugammadex (MK-8616) for Reversal of Neuromuscular Blockade in Pediatric Participants Aged Birth to <2 Years (MK-8616-169)

This study will evaluate the efficacy, safety, and pharmacokinetics (PK) of sugammadex (MK-8616) for reversal of both moderate and deep neuromuscular blockade (NMB) in pediatric participants aged birth to <2 years. The primary hypothesis of this study is that sugammadex is superior to neostigmine in reversing moderate NMB as measured …

atropine
glycopyrrolate
neostigmine
sugammadex
intubation
Children's Hospital of Pittsburgh UPMC ( Site 3017)
 (9.9 away) Contact site
  • 4 views
  • 26 May, 2021
  • +35 other locations
A Study to Evaluate the Efficacy and Safety of Erenumab in Adults With Medication Overuse Headache

Study 20170703 is a phase 4, randomized, double-blind, parallel-group, placebo-controlled study to evaluate the efficacy and safety of erenumab against placebo in subjects with chronic migraine (CM) who have a history of at least 1 preventive treatment failure and are diagnosed with medication overuse headache (MOH).

acute migraine
erenumab
preventive medication
experimental drug
chronic migraine
West Pennsylvania Hospital
 (9.9 away) Contact site
  • 359 views
  • 09 Jun, 2021
  • +167 other locations
A Study of Pembrolizumab (MK-3475) Plus Carboplatin and Paclitaxel as First-line Treatment of Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (MK-3475-B10/KEYNOTE B10)

The goal of this study is to evaluate the efficacy and safety of pembrolizumab combined with carboplatin and paclitaxel as first line treatment in participants with recurrent/metastatic head and neck squamous cell carcinoma (R/M HNSCC). No statistical hypothesis will be tested in this study.

metastatic head and neck squamous cell carcinoma
pembrolizumab
carcinoma
carboplatin
mk-3475
UPMC Hillman Cancer Center ( Site 0253)
 (9.1 away) Contact site
  • 0 views
  • 07 Jun, 2021
  • +24 other locations
Radium-223 Dichloride Long-term Follow-up Program

Patients will be followed up in this study after prior treatment with BAY88-8223 / Radium-223 dichloride / Xofigo .

 (9.9 away) Contact site
  • 0 views
  • 29 May, 2021
  • +130 other locations
GM-CSF for Reversal of immunopAralysis in pediatriC sEpsis-induced MODS Study

This study is an open-label, multi-center, interventional trial in which children with sepsis-induced MODS undergo surveillance immune function testing beginning on Day 2 of MODS. Those children who demonstrate immunoparalysis (TNF-alpha response <200 pg/ml) will receive a 7-day course of GM-CSF at a dose of 125 or 250 mcg/m2/day by …

Children's Hospital of Pittsburgh
 (9.9 away) Contact site
  • 6 views
  • 09 Apr, 2021
  • +7 other locations
Single vs. Multiple Privigen Dose Regimens in Pediatric CIDP

A randomized, open-label, prospective, multicenter study designed to investigate 2 dose regimens in pediatric subjects 2 to < 17 years of age with confirmed or possible CIDP, either previously exposed to IVIG treatment or unexposed to IVIG treatment

University of Pittsburgh
 (9.9 away) Contact site
  • 35 views
  • 04 Mar, 2021
  • +12 other locations