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Havertown, Pennsylvania Clinical Trials

A listing of Havertown, Pennsylvania clinical trials actively recruiting patient volunteers.

RESULTS

Found (19) clinical trials

Evaluation of Safety and Efficacy of Avacopan in Subjects With Moderate to Severe Hidradenitis Suppurativa

A Randomized, Double-Blind, Placebo-Controlled, Parallel Group, Phase 2 study in subjects with moderate to severe Hidradenitis Suppurativa. The study is multicenter and will consist of three subject groups. Subjects will be randomized 1:1:1 to a treatment of 10mg avacopan twice daily, 30 mg avacopan twice daily or placebo twice daily ...

Phase

1.9 miles

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Cognition and Psychotherapy in PTSD

Accumulating evidence indicates that memory dysfunction: 1) is prominent in PTSD; and 2) adversely affects psychotherapy outcomes. Identifying mechanisms underlying the relationship between memory dysfunction and poor treatment outcomes is crucial to provide empirical guidance regarding appropriate rehabilitation targets to reduce the impact of cognitive dysfunction on therapy outcomes. In ...

Phase N/A

5.86 miles

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Multicenter Study of Patient-reported Gastrointestinal Symptoms in People With Cystic Fibrosis

There are currently no large, multicenter prospective clinical trials examining management of constipation or other gastrointestinal (GI) symptoms in people with cystic fibrosis (CF). Current recommendations in the CF literature are largely based on expert consensus and opinions. Yet, constipation and other GI symptoms are crucial factors in quality of ...

Phase N/A

5.86 miles

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Efficacy and Safety of Cannabidiol Oral Solution (GWP42003-P CBD-OS) in Patients With Rett Syndrome

To evaluate the efficacy of cannabidiol oral solution (GWP42003-P, CBD-OS) in reducing symptom severity when compared with placebo, in patients with Rett syndrome.

Phase

5.86 miles

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Trial to Evaluate Efficacy and Safety of Lenabasum in Dermatomyositis

Subjects will be randomized to receive lenabasum 20 mg twice per day, lenabasum 5 mg twice per day, or placebo twice per day in a 2:1:2 ratio. The primary efficacy outcome at Week 52 will be Total Improvement Score (TIS), which is a weighted composite measure of improvement from baseline ...

Phase

5.86 miles

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Open Label Study of mRNA-3704 in Patients With Isolated Methylmalonic Acidemia

This First-in-Human (FIH) Phase 1/2 study will evaluate mRNA-3704 in patients with methylmalonic acidemia/aciduria (MMA) due to methylmalonyl-coenzyme A mutase (MUT) deficiency between 1 to 18 years of age with elevated plasma methylmalonic acid. The study is designed to characterize baseline biomarker levels followed by assessment of safety, pharmacokinetics, and ...

Phase

5.86 miles

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JAK Inhibitor Treatment in AGS

Aicardi Goutires Syndrome (AGS) is a multisystem heritable disorder of the innate immunity resulting in excessive interferon production. Most characteristically, AGS manifests as an early-onset encephalopathy that results in severe intellectual and physical handicap. Interferon is thought to cause injury not only to the brain, but also the skin, liver, ...

Phase

5.86 miles

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Pharmacokinetic (PK) and Pharmacodynamics (PD) Study of Ilera Specific Products

This is a prospective PK/PD study that will include patients who are currently legally consuming one of the four medical marijuana formulations (Dream, Soothe, Shine and Ease) from Ilera Healthcare as part of their standard therapy for one of the state approved serious medical conditions. Part 1 of the study ...

Phase N/A

5.86 miles

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Ribociclib in Combination With Everolimus and Dexamethasone in Relapsed ALL

This research study is a Phase I clinical trial, which tests the safety of an investigational drug or a combination of drugs. Phase I studies try to define the appropriate dose of the investigational drug to use for further studies. "Investigational" means that the drug and the combination of drugs ...

Phase

5.86 miles

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Prospective Assessment of Premature Ventricular Contractions Suppression in Cardiomyopathy(PAPS)

Rationale. Frequent PVCs have shown to induce a reversible cardiomyopathy (PVC-CM). Yet, it is unclear why some patients develop PVC-CM, while others do not. Appropriate diagnosis and treatment of patients with PVC-CM is believed to carry significant benefits, improving quality of life (QOL), HF symptoms / admissions and life expectancy. ...

Phase

5.86 miles

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