Garfield Heights, Ohio Clinical Trials

A listing of Garfield Heights, Ohio clinical trials actively recruiting patient volunteers.

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Found 886 clinical trials
A Study of Heterologous Vaccine Regimen of Adenovirus Serotype 26 Mosaic4 Human Immunodeficiency Virus(Ad26.Mos4.HIV) Adjuvanted Clade C gp140 and Mosaic gp140 to Prevent HIV-1 Infection Among Cis-gender Men and Transgender Individuals Who Have Sex With Cis-gender Men and/or Transgender Individuals

The purpose of this study is to evaluate the vaccine efficacy (VE) of a heterologous vaccine regimen utilizing Ad26.Mos4.HIV and aluminum phosphate-adjuvanted Clade C gp140 and Mosaic gp140 for the prevention of HIV-1 infection in HIV-1 seronegative cis-gender men and transgender individuals having sex with cis-gender men and/or transgender individuals.

University Hospitals Cleveland Medical Center
 (6.3 away) Contact site
  • 74 views
  • 28 Jun, 2021
  • +78 other locations
A Study to Assess the Efficacy and Safety of Efgartigimod in Adult Patients With Primary Immune Thrombocytopenia (ITP).

This is a randomized, double-blind placebo-controlled multicenter phase 3 trial to evaluate the efficacy and safety of ARGX-113 in patients with primary ITP.

Investigator Site 80
 (6.0 away) Contact site
  • 28 views
  • 10 Jul, 2021
  • +241 other locations
Enfortumab Vedotin and Pembrolizumab vs. Chemotherapy Alone in Untreated Locally Advanced or Metastatic Urothelial Cancer

This study is being done to see how well two drugs (enfortumab vedotin and pembrolizumab) work together to treat patients with urothelial cancer. The study will compare these drugs to other drugs that are usually used to treat this cancer (standard of care). The patients in this study will have …

systemic therapy
carcinoma
measurable disease
pd-l1
pembrolizumab
The Cleveland Clinic
 (6.0 away) Contact site
  • 5 views
  • 21 Jul, 2021
  • +111 other locations
Durvalumab vs Placebo With Stereotactic Body Radiation Therapy in Early Stage Unresected Non-small Cell Lung Cancer Patients

This is a Phase III, randomized, placebo-controlled, double-blind, multi-center study assessing the efficacy and safety of durvalumab with SoC SBRT versus placebo with SoC SBRT in patients with unresected clinical Stage I/II lymph node-negative (T1 to T3N0M0) NSCLC.

lung carcinoma
durvalumab
stereotactic body radiation therapy
Research Site
 (6.3 away) Contact site
  • 68 views
  • 28 Apr, 2021
  • +226 other locations
LUMINA Phase III Study Assessing the Efficacy and Safety of Intravitreal Injections of 440 ug DE-109 Sirolimus for the Treatment of Active Non-Infectious Uveitis of the Posterior Segment of the Eye

This is a Phase III study to assess the efficacy and safety of DE-109 440 g every 2 months in subjects with active, non-infectious uveitis of the posterior segment of the eye (NIU-PS). There is a 6-month, single-arm, open-label period after completion of the 6-month doublemasked, controlled period allows the …

Retina Associate of Cleveland
 (5.6 away) Contact site
  • 126 views
  • 09 Jul, 2021
  • +89 other locations
Efficacy and Safety APT-1011 in Subjects With Eosinophilic Esophagitis (EoE) (FLUTE-2)

This is a 2-part randomized, double-blind, placebo-controlled study of APT-1011 in adults and adolescents (12 years) with EoE. Part A will evaluate the efficacy and safety of APT-1011 3 mg administered HS for the induction of response to treatment (histologic and symptomatic) over 12 weeks. Part B will evaluate histological …

dysphagia
esophagogastroduodenoscopy
Gastroenterology Associates of Cleveland, Inc / Great Lakes Medical Research LLC
 (6.0 away) Contact site
  • 93 views
  • 19 Jul, 2021
  • +141 other locations
Establishing the Safety and Efficacy of Reloxaliase in Patients With Enteric Hyperoxaluria

The purpose of this study is to determine the efficacy, durability and long-term safety of reloxaliase in patients with enteric hyperoxaluria.

Clinical Research Solutions- Middleburg Heights
 (8.8 away) Contact site
  • 7 views
  • 22 Jul, 2021
  • +83 other locations
Capivasertib+Fulvestrant vs Placebo+Fulvestrant as Treatment for Locally Advanced (Inoperable) or Metastatic HR+/HER2- Breast Cancer

Phase III, double-blind, randomised study assessing the efficacy of capivasertib + fulvestrant vs placebo + fulvestrant for the treatment of patients with locally advanced (inoperable) or metastatic HR+/HER2- breast cancer following recurrence or progression on or after AI therapy.

Research Site
 (6.3 away) Contact site
  • 50 views
  • 11 Jul, 2021
  • +223 other locations
IMG-7289 in Patients With Essential Thrombocythemia

This is a Phase 2b open label study of an orally administered LSD1 inhibitor, IMG-7289, in patients with essential thrombocythemia. This study investigates the following: The safety and tolerability of IMG-7289 The pharmacodynamic effect of IMG-7289

thrombosis
platelet count
interferon
thrombocytosis
Cleveland Clinic
 (6.0 away) Contact site
  • 0 views
  • 25 Jul, 2021
  • +5 other locations
A Long-term Study of Nemolizumab (CD14152) in Participants With Prurigo Nodularis (PN)

The primary purpose of this study is to assess the long-term safety of nemolizumab (CD14152) in participants with prurigo nodularis (PN).

Galderma Investigational Site
 (6.3 away) Contact site
  • 0 views
  • 25 Jul, 2021
  • +140 other locations