New York, New York Clinical Trials

A listing of New York, New York clinical trials actively recruiting patient volunteers.

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Found 3492 clinical trials
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Study of Oral Navitoclax Tablet in Combination With Oral Ruxolitinib Tablet to Assess Change in Spleen Volume in Adult Participants With Relapsed/Refractory Myelofibrosis

www.MyelofibrosisResearch.com Myelofibrosis (MF) is a bone marrow illness that affects blood-forming tissues in the body. MF disturbs the body's normal production of blood cells, causing extensive scarring in the bone marrow. This leads to severe anemia, weakness, fatigue, and an enlarged spleen. The purpose of this study is to assess …

Weill Cornell Medical College /ID# 220866
 (4.9 away) Contact site
  • 226 views
  • 29 Apr, 2021
  • +224 other locations
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Study of Oral Navitoclax Tablet In Combination With Oral Ruxolitinib Tablet When Compared With Oral Ruxolitinib Tablet To Assess Change In Spleen Volume In Adult Participants With Myelofibrosis

www.MyelofibrosisResearch.com Myelofibrosis is a type of bone marrow cancer that usually develops slowly and disrupts body's normal production of blood cells. It causes bone marrow scarring, leading to severe anemia that can cause weakness and fatigue. It can also cause a low number of blood-clotting cells called platelets, which increases …

Weill Cornell Medical College /ID# 220933
 (4.9 away) Contact site
  • 87 views
  • 29 Apr, 2021
  • +148 other locations
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Study in Parkinson Disease of Exercise

This study is a Phase 3 multi-site, randomized, evaluator-masked, study of endurance treadmill exercise on changes in the Movement Disorder Society-Unified Parkinson Disease Rating Scale (MDS-UPDRS) Part III score at 12 months among persons with early stage Parkinson disease. 370 participants will be randomly assigned to 2 groups: 1)60-65% HRmax …

New York University Langone Health
 (6.9 away) Contact site
  • 7 views
  • 04 Jun, 2021
  • +7 other locations
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A Study Evaluating Safety and Tolerability and Pharmacokinetics of Navitoclax Monotherapy and in Combination With Ruxolitinib in Participants With Myeloproliferative Neoplasm

www.myelofibrosisresearch.com There are 4 parts to this study for which the primary objectives are to evaluate safety, tolerability, and pharmacokinetics (PK) of navitoclax when administered alone (Part 1) or when administered in combination with ruxolitinib (Part 2). In Part 2, participants must have been receiving a stable dose of ruxolitinib …

polycythemia vera
stem cell transplantation
myelofibrosis
polycythemia
thrombocytosis
Columbia Univ Medical Center /ID# 223384
 (0.2 away) Contact site
  • 1 views
  • 01 Sep, 2021
  • +36 other locations
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The RADIANCE II Pivotal Study: A Study of the ReCor Medical Paradise System in Stage II Hypertension

The objective of the RADIANCE II Pivotal study is to demonstrate the effectiveness and safety of the Paradise System in subjects with Stage 2 hypertension on 0-2 medications at the time of consent. Prior to randomization, subjects will be hypertensive in the absence of hypertension medication.

antihypertensive therapy
hypertensive medication
hypertension
renal angiogram
angiography
Columbia University Medical Center/NYPH
 (0.2 away) Contact site
  • 897 views
  • 10 Sep, 2021
  • +82 other locations
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A Phase 2, Open-Label, Randomized, Multicenter Study to Evaluate the Efficacy and Safety of Pemigatinib Plus Pembrolizumab Versus Pemigatinib Alone Versus Standard of Care as First-Line Treatment for Metastatic or Unresectable Urothelial Carcinoma in Cisplatin-Ineligible Participants Whose Tumors Express FGFR3 Mutation or Rearrangement

The purpose of this study is to evaluate the safety and efficacy of pemigatinib plus pembrolizumab or pemigatinib alone versus the standard of care for participants with metastatic or unresectable urothelial carcinoma who are not eligible to receive cisplatin, are harboring FGFR3 mutation or rearrangement, and who have not received …

urothelial carcinoma
bladder carcinoma
metastatic urothelial carcinoma
bladder cancer
Mount Sinai School of Medicine
 (3.4 away) Contact site
  • 29 views
  • 14 Dec, 2020
  • +63 other locations
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A Phase 2, Open-Label Study of INCB050465 in Participants With Autoimmune Hemolytic Anemia

The purpose of this study is to evaluate the safety and efficacy of INCB050465 administered orally to participants with autoimmune hemolytic anemia (AIHA) who have decreased hemoglobin and evidence of ongoing hemolysis that requires treatment intervention.

anemia
WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY
 (5.3 away) Contact site
  • 68 views
  • 25 Aug, 2021
  • 1 location
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A Study to Evaluate the Efficacy and Safety of Pemigatinib Versus Chemotherapy in Unresectable or Metastatic Cholangiocarcinoma - (FIGHT-302)

The purpose of this study is to evaluate the efficacy and safety of pemigatinib versus gemcitabine plus cisplatin chemotherapy in first-line treatment of participants with unresectable or metastatic cholangiocarcinoma with FGFR2 rearrangement.  

metastatic cancer
cancer
primary cancer
FGFR2
Mt. Sinai Hospital
 (3.4 away) Contact site
  • 173 views
  • 25 Aug, 2021
  • +145 other locations
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C1071003 MagnetisMM-3

The purpose of the study is to evaluate whether single-agent PF-06863135 can provide clinical benefit in participants with relapsed/refractory multiple myeloma. PF-06863135 is a bispecific antibody: binding of PF-06863135 to CD3-expressing T-cells and BCMA-expressing multiple myeloma cells causes targeted T-cell-mediated cytotoxicity.

refractory multiple myeloma
Memorial Sloan Kettering Cancer Center
 (5.3 away) Contact site
  • 1 views
  • 23 Sep, 2021
  • +4 other locations
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C3671008 Matisse

This randomized, double-blinded, placebo-controlled Phase 3 study is designed to evaluate the efficacy and safety of maternal immunization with RSVpreF against medically attended lower respiratory tract illness (MA-LRTI) in infants.

Columbia University Irving Medical Center
 (5.6 away) Contact site
  • 151 views
  • 16 Sep, 2021
  • +159 other locations