Winston Salem, North Carolina Clinical Trials

A listing of Winston Salem, North Carolina clinical trials actively recruiting patient volunteers.

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Found 174 clinical trials
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The Axcelsius Study: A Study of ONO-7475 in Patients with Acute Leukemias

What is the Axcelsius study? The Axcelsius study is a clinical research study being conducted to determine the safety and tolerability of the study drug called ONO-7475. ONO-7475 has been tested in AML patients and was confirmed safe and tolerable at a dose to be used in the study. Previous …

induction chemotherapy
acute leukemia
refractory acute myeloid leukemia (aml)
remission
leukemia
Wake Forest Baptist Health
 (2.8 away) Contact site
  • 0 views
  • 23 Jul, 2021
  • +2 other locations
Efficacy and Safety of Tezepelumab in Participants With Severe Chronic Rhinosinusitis With Nasal Polyposis

A Multicentre, Randomised, Double-Blind, Parallel-Group, Placebo-Controlled Phase 3 Efficacy and Safety Study of Tezepelumab in Participants with Severe Chronic Rhinosinusitis with Nasal Polyposis

Research Site
 (1.2 away) Contact site
  • 0 views
  • 24 Jul, 2021
  • +116 other locations
Effect of Sodium Zirconium Cyclosilicate on Arrythmia-related Cardiovascular Outcomes in Participants on Chronic Hemodialysis With Recurrent Hyperkalemia (DIALIZE-Outcomes)

The purpose of this study is to evaluate the effect of Sodium Zirconium Cyclosilicate (SZC) on arrhythmia-related cardiovascular outcomes in participants on chronic hemodialysis with recurrent hyperkalemia.

Research Site
 (1.2 away) Contact site
  • 0 views
  • 02 Aug, 2021
  • +252 other locations
ACTIV-6: COVID-19 Study of Repurposed Medications

The purpose of this study is to evaluate the effectiveness of repurposed medications (study drug(s) in reducing symptoms of non-hospitalized participants with mild to moderate COVID-19. Participants will receive either study drug or placebo. They will self-report any new or worsening symptoms or medical events they may experience while taking …

Wake Forest Baptist Health
 (5.2 away) Contact site
  • 0 views
  • 02 Aug, 2021
  • +3 other locations
Phase 4 Comparative Trial of Benzathine Penicillin G for Treatment of Early Syphilis in Subjects With or Without HIV Infection

This is a phase 4, randomized, open-label, multicenter trial to evaluate the efficacy of a single injected dose of Benzathine Penicillin G (BPG) 2.4 MU (Arm 1) compared to three successive weekly injected doses of BPG 2.4 MU (Arm 2) for treatment of early syphilis in human immunodeficiency virus (HIV)-infected …

hysterectomy
early latent syphilis
early syphilis
penicillin
rpr test
Wake Forest Baptist Health - Infectious Diseases
 (5.2 away) Contact site
  • 38 views
  • 04 Aug, 2021
  • +11 other locations
Study of AMG 650 in Adult Participants With Advanced Solid Tumors

To evaluate the safety and tolerability of AMG 650 in adult participants and to determine the maximum tolerated dose (MTD) and/or recommended phase 2 dose (RP2D).

Research Site
 (1.2 away) Contact site
  • 17 views
  • 23 Jul, 2021
  • +40 other locations
Study of Evobrutinib in Participants With RMS (evolutionRMS 2)

The study is to evaluate the efficacy and safety of evobrutinib administered orally twice daily versus Teriflunomide (Aubagio), administered orally once daily in participants with Relapsing Multiple Sclerosis (RMS).

evobrutinib
teriflunomide
aubagio
Research Site 728
 (2.8 away) Contact site
  • 0 views
  • 31 Jul, 2021
  • +258 other locations
A Study to Assess the Efficacy Safety and Tolerability of Brensocatib in Participants With Non-Cystic Fibrosis Bronchiectasis

The primary objective of this study is to evaluate the effect of brensocatib at 10 mg and 25 mg compared with placebo on the rate of pulmonary exacerbations (PEs) over the 52-week treatment period.

USA026
 (6.9 away) Contact site
  • 3 views
  • 01 Aug, 2021
  • +258 other locations
A Study of Benralizumab in Patients With Eosinophilic Esophagitis

The aim of this Phase 3 study is to investigate the use of benralizumab as a treatment for patients with EoE. The effect of doses of benralizumab on EoE histologic signs and symptoms will be assessed over a 52-week treatment period (including a 24-week double-blind placebo-controlled treatment period and a …

Research Site
 (2.8 away) Contact site
  • 1 views
  • 26 Jul, 2021
  • +83 other locations
A Long-term Study of Nemolizumab (CD14152) in Participants With Prurigo Nodularis (PN)

The primary purpose of this study is to assess the long-term safety of nemolizumab (CD14152) in participants with prurigo nodularis (PN).

Galderma Investigational Site
 (5.8 away) Contact site
  • 0 views
  • 30 Jul, 2021
  • +140 other locations