Wilmington, North Carolina Clinical Trials

A listing of Wilmington, North Carolina clinical trials actively recruiting patient volunteers.

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Found 46 clinical trials
PRISM Study-Pruritus Relief Through Itch Scratch Modulation

To investigate the anti-pruritic efficacy and safety of Nalbuphine ER (NAL ER) tablets in Prurigo Nodularis. Subjects will be randomized to NAL ER (or matching placebo) with the primary endpoint evaluation at Week 14. During the open label extension, subjects who received NAL ER will continue on NAL ER and …

nalbuphine
Study Site 101
 (9.6 away) Contact site
  • 661 views
  • 31 Jul, 2021
  • +85 other locations
Study to Evaluate Adverse Events and Change in Disease Activity in Participants Between 18 to 75 Years of Age Treated With Subcutaneous (SC) Injections of ABBV-154 for Moderately to Severely Active Rheumatoid Arthritis (RA)

Rheumatoid Arthritis (RA) is an inflammatory disease of the joints causing pain, stiffness, swelling and loss of joint function. This study evaluates how safe and effective ABBV-154 is in participants treated for moderately to severely active RA. Adverse events and change in the disease activity will be assessed. ABBV-154 is …

antirheumatics
rheumatism
methotrexate
stiffness
Cape Fear Arthritis Care /ID# 228747
 (5.1 away) Contact site
  • 0 views
  • 04 Aug, 2021
  • +292 other locations
Long-term Safety and Efficacy of Nemolizumab With Moderate-to-severe Atopic Dermatitis

Long-Term Safety and Efficacy of Nemolizumab in Subjects with Moderate-to-Severe Atopic Dermatitis Description

Galderma Investigational Site
 (5.2 away) Contact site
  • 21 views
  • 04 Aug, 2021
  • +474 other locations
A Study To Assess the Safety and Effects of OnabotulinumtoxinA (BOTOX) Intramuscular Injection in Adult Participants With Moderate to Severe Platysma Prominence

The purpose of the study is to evaluate the safety and effects of onabotulinumtoxinA (BOTOX) for the temporary improvement in the appearance of platysma prominence. Study doctors will randomize participants into 1 of the 2 groups, called treatment arms. There is a 1 in 2 chance that a participant will …

Wilmington Dermatology Center /ID# 229246
 (4.2 away) Contact site
  • 0 views
  • 04 Aug, 2021
  • +30 other locations
A Long-term Study to Evaluate Safety and Maintenance of Treatment Effect of LY3074828 in Participants With Moderate-to-Severe Plaque Psoriasis (OASIS-3)

The purpose of this study is to evaluate the long-term safety and maintenance of efficacy of mirikizumab in participants with moderate-to-severe plaque psoriasis.

mirikizumab
plaque psoriasis
PMG Research of Wilmington, LLC
 (9.6 away) Contact site
  • 717 views
  • 27 Jul, 2021
  • +354 other locations
A Study of the Efficacy and Safety of Relacorilant in Patients With Endogenous Cushing Syndrome

This is a Phase 3, double-blind, placebo-controlled, randomized-withdrawal study to assess the efficacy, safety and pharmacokinetics (PK) of relacorilant in patients with endogenous Cushing syndrome and concurrent type 2 diabetes mellitus/impaired glucose tolerance and/or uncontrolled hypertension

relacorilant
diabetes
hypertension
Site 5
 (154.5 away) Contact site
  • 113 views
  • 04 Aug, 2021
  • +69 other locations
Randomized Placebo-controlled Trial of FCM as Treatment for Heart Failure With Iron Deficiency

The primary objective of this study is to determine the efficacy and safety of iron therapy using intravenous (IV) ferric carboxymaltose (FCM), relative to placebo in the treatment of participants in heart failure with a reduced ejection fraction and with iron deficiency

cardiac resynchronization therapy
iron
ejection fraction
bypass graft
nesiritide
Duke Cardiology of Lumberton
 (66.5 away) Contact site
  • 5316 views
  • 02 Aug, 2021
  • +365 other locations
A Study to Evaluate the Effect of Testosterone Replacement Therapy (TRT) on the Incidence of Major Adverse Cardiovascular Events (MACE) and Efficacy Measures in Hypogonadal Men

This is a blinded and placebo-controlled study of topical testosterone replacement therapy (TRT) in symptomatic hypogonadal men with increased risk for cardiovascular (CV) disease.

serum testosterone
testosterone level
replacement therapy
testosterone topical
testosterone
Goshen Medical Center - Vineland /ID# 170342
 (43.8 away) Contact site
  • 16879 views
  • 30 Jul, 2021
  • +485 other locations
A Research Study to Compare a New Weekly Insulin Insulin Icodec and an Available Daily Insulin Insulin Degludec Both in Combination With Mealtime Insulin in People With Type 1 Diabetes (ONWARDS 6)

This study compares insulin icodec (a new insulin) to insulin degludec (an insulin already available on the market) in people with type 1 diabetes. The study will look at how well insulin icodec taken weekly controls blood sugar compared to insulin degludec taken daily. Participants will either get insulin icodec …

Novo Nordisk Investigational Site
 (251.9 away) Contact site
  • 0 views
  • 04 Aug, 2021
  • +80 other locations
A Study of Baricitinib in Participants With Rheumatoid Arthritis

This post-marketing study is designed to compare the safety of baricitinib versus tumor necrosis factor (TNF) inhibitors with respect to venous thromboembolic events (VTEs) when given to participants with rheumatoid arthritis (RA).

tumor necrosis factor
tumour necrosis
antirheumatics
tumor necrosis factor alpha
baricitinib
Carolina Arthritis Associates
 (5.8 away) Contact site
  • 301 views
  • 24 Jul, 2021
  • +167 other locations