Statesville, North Carolina Clinical Trials

A listing of Statesville, North Carolina clinical trials actively recruiting patient volunteers.

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Found 15 clinical trials
A 12-Month Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With Migraine

The reason for this 12-month, open-label study is to see if the study drug lasmiditan is safe and effective for the intermittent acute treatment of migraine in children aged 6 to 17. The study will last about 12 months and may include up to 7 visits.

ly573144
lasmiditan
acute treatment
migraine in children
PMG Research of Piedmont Healthcare
 (5.7 away) Contact site
  • 129 views
  • 24 Jul, 2021
  • +238 other locations
CompassHER2-pCR: Decreasing Chemotherapy for Breast Cancer Patients After Pre-surgery Chemo and Targeted Therapy

This trial studies how well paclitaxel, trastuzumab, and pertuzumab work in eliminating further chemotherapy after surgery in patients with HER2-positive stage II-IIIa breast cancer who have no cancer remaining at surgery (either in the breast or underarm lymph nodes) after pre-operative chemotherapy and HER2-targeted therapy. Drugs used in chemotherapy, such …

chemotherapy drugs
estrogen receptor
HER2
core needle biopsy
hepatitis b
Novant Health Cancer Institute - Statesville
 (5.7 away) Contact site
  • 43 views
  • 01 Aug, 2021
  • +576 other locations
Linaclotide Safety and Efficacy in Pediatric Participants 6 to 17 Years of Age With Irritable Bowel Syndrome With Constipation (IBS-C) or Functional Constipation (FC)

The objective of LIN-MD-64 is to evaluate the safety and efficacy of 12 weeks of linaclotide therapy (72 g daily) in comparison with placebo in pediatric participants, 6 to 17 years of age, who fulfill modified Rome III Criteria for Child/Adolescent Functional Constipation (FC). The objective of LIN-MD-64 is to …

laxative
posturing
incontinence
PMG Research, Inc. dba PMG Research of Piedmont Healthcare
 (5.7 away) Contact site
  • 136 views
  • 04 Aug, 2021
  • +298 other locations
A Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With Migraine

The reason for this study is to see if lasmiditan is safe and effective in children aged 6 to 17 with migraine. The study will last up to 20 weeks and may include up to 4 visits.

ly573144
preventive medication
lasmiditan
headache
PMG Research of Piedmont Healthcare
 (5.7 away) Contact site
  • 122 views
  • 26 Jul, 2021
  • +237 other locations
Study of Safety Efficacy and Tolerability of Secukinumab Versus Placebo in Combination With SoC Therapy in Patients With Active Lupus Nephritis

The purpose of this trial is to evaluate the efficacy and safety of subcutaneous secukinumab 300 mg compared to placebo, in combination with standard of care therapy (SoC), in subjects with active lupus nephritis (ISN/RPS Class III or IV, with or without co-existing class V features).

mammogram
nephritis
glomerular filtration rate
urinary sediment
Novartis Investigative Site
 (371.6 away) Contact site
  • 37 views
  • 30 Jul, 2021
  • +122 other locations
Testing Immunotherapy Versus Observation in Patients With HPV Throat Cancer

This phase II/III trials studies whether maintenance immunotherapy (nivolumab) following definitive treatment with radiation and chemotherapy (cisplatin) result in significant improvement in overall survival (time being alive) and progression-free survival (time being alive without cancer) for patients with intermediate risk human papillomavirus (HPV) positive oropharynx cancer (throat cancer) that has …

Novant Health Cancer Institute - Statesville
 (5.7 away) Contact site
  • 135 views
  • 04 Aug, 2021
  • +539 other locations
Immunotherapy (Nivolumab or Brentuximab Vedotin) Plus Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage III-IV Classic Hodgkin Lymphoma

This phase III trial compares immunotherapy drugs (nivolumab or brentuximab vedotin) when given with combination chemotherapy in treating patients with newly diagnosed stage III or IV classic Hodgkin lymphoma. Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's immune system attack the cancer, and may interfere with the …

classical hodgkin lymphoma
human immunodeficiency virus
vinblastine
dacarbazine
mixed cellularity hodgkin lymphoma
Novant Health Oncology Specialists-Statesville
 (5.7 away) Contact site
  • 68 views
  • 04 Aug, 2021
  • +507 other locations
Chemoradiation With or Without Atezolizumab in Treating Patients With Limited Stage Small Cell Lung Cancer

This phase III trial studies how well chemotherapy and radiation therapy (chemoradiation) with or without atezolizumab works in treating patients with limited stage small cell lung cancer. Drugs used in chemotherapy, such as etoposide, cisplatin, and carboplatin, work in different ways to stop the growth of tumor cells, either by …

Novant Health Oncology Specialists-Wilkesboro
 (26.8 away) Contact site
  • 85 views
  • 04 Aug, 2021
  • +334 other locations
Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With Cabozantinib for Patients With Advanced Kidney Cancer The PDIGREE Study

This phase III trial compares the usual treatment (treatment with ipilimumab and nivolumab followed by nivolumab alone) to treatment with ipilimumab and nivolumab, followed by nivolumab with cabozantinib in patients with untreated renal cell carcinoma that has spread to other parts of the body. The addition of cabozantinib to the …

carcinoma
step 2
calcium
metastatic renal cell carcinoma
programmed cell death 1 ligand 1
Novant Health Cancer Institute - Statesville
 (5.7 away) Contact site
  • 157 views
  • 04 Aug, 2021
  • +680 other locations
Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors Lymphomas or Multiple Myeloma (The MATCH Screening Trial)

This phase II MATCH trial studies how well treatment that is directed by genetic testing works in patients with solid tumors or lymphomas that have progressed following at least one line of standard treatment or for which no agreed upon treatment approach exists. Genetic tests look at the unique genetic …

human immunodeficiency virus
immunohistochemistry
crizotinib
erdafitinib
cytology specimen collection procedure
Novant Health Cancer Institute - Statesville
 (5.7 away) Contact site
  • 6088 views
  • 04 Aug, 2021
  • +1020 other locations