Southern Pines, North Carolina Clinical Trials

A listing of Southern Pines, North Carolina clinical trials actively recruiting patient volunteers.

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Found 22 clinical trials
Efficacy and Safety of APP13007 for Treatment of Inflammation and Pain After Cataract Surgery

This Phase 3 study will evaluate APP13007 in comparison to the matching vehicle placebo in a randomized, parallel-group, double-masked fashion. The subjects will have undergone routine cataract surgery on Day 0 of the study and will be assessed the next day (Post-operative Day 1; POD1) after uncomplicated surgery for eligibility …

Coastal Research Associates, LLC
 (289.4 away) Contact site
  • 0 views
  • 28 Jul, 2021
  • +31 other locations
Vitamin D3 With Chemotherapy and Bevacizumab in Treating Patients With Advanced or Metastatic Colorectal Cancer

This phase III trial studies how well vitamin D3 given with standard chemotherapy and bevacizumab works in treating patients with colorectal cancer that has spread to other parts of the body. Vitamin D3 helps the body use calcium and phosphorus to make strong bones and teeth. Drugs used in chemotherapy, …

liver metastasis
fluorouracil
metastasis
monoclonal antibodies
cancer treatment
FirstHealth of the Carolinas-Moore Regional Hospital
 (4.5 away) Contact site
  • 72 views
  • 27 Jul, 2021
  • +978 other locations
Genetic Testing in Screening Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been or Will Be Removed by Surgery (The ALCHEMIST Screening Trial)

This ALCHEMIST trial studies genetic testing in screening patients with stage IB-IIIA non-small cell lung cancer that has been or will be removed by surgery. Studying the genes in a patient's tumor cells may help doctors select the best treatment for patients that have certain genetic changes.

metastasis
paclitaxel
pemetrexed
squamous cell carcinoma
pembrolizumab
FirstHealth of the Carolinas-Moore Regional Hospital
 (4.5 away) Contact site
  • 1103 views
  • 04 Aug, 2021
  • +1138 other locations
Cediranib Maleate and Olaparib or Standard Chemotherapy in Treating Patients With Recurrent Platinum-Resistant or -Refractory Ovarian Fallopian Tube or Primary Peritoneal Cancer

This randomized phase II/III trial studies how well cediranib maleate and olaparib work when given together or separately, and compares them to standard chemotherapy in treating patients with ovarian, fallopian tube, or primary peritoneal cancer that has returned (recurrent) after receiving chemotherapy with drugs that contain platinum (platinum-resistant) or continued …

liver metastasis
metastasis
paclitaxel
topotecan
thyroid dysfunction
FirstHealth of the Carolinas-Moore Regional Hospital
 (4.3 away) Contact site
  • 1729 views
  • 02 Aug, 2021
  • +211 other locations
Randomized Placebo-controlled Trial of FCM as Treatment for Heart Failure With Iron Deficiency

The primary objective of this study is to determine the efficacy and safety of iron therapy using intravenous (IV) ferric carboxymaltose (FCM), relative to placebo in the treatment of participants in heart failure with a reduced ejection fraction and with iron deficiency

nesiritide
ejection fraction
nt-probnp
cardiac resynchronization therapy
b-type natriuretic peptide
Pinehurst Medical Clinic, Inc.
 (4.3 away) Contact site
  • 5316 views
  • 02 Aug, 2021
  • +365 other locations
Immunotherapy (Nivolumab or Brentuximab Vedotin) Plus Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage III-IV Classic Hodgkin Lymphoma

This phase III trial compares immunotherapy drugs (nivolumab or brentuximab vedotin) when given with combination chemotherapy in treating patients with newly diagnosed stage III or IV classic Hodgkin lymphoma. Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's immune system attack the cancer, and may interfere with the …

dacarbazine
monoclonal antibodies
alopecia
cell transplantation
mixed cellularity hodgkin lymphoma
FirstHealth of the Carolinas-Moore Regional Hospital
 (4.5 away) Contact site
  • 68 views
  • 04 Aug, 2021
  • +507 other locations
Chemoradiation With or Without Atezolizumab in Treating Patients With Limited Stage Small Cell Lung Cancer

This phase III trial studies how well chemotherapy and radiation therapy (chemoradiation) with or without atezolizumab works in treating patients with limited stage small cell lung cancer. Drugs used in chemotherapy, such as etoposide, cisplatin, and carboplatin, work in different ways to stop the growth of tumor cells, either by …

FirstHealth of the Carolinas-Moore Regional Hospital
 (4.5 away) Contact site
  • 85 views
  • 04 Aug, 2021
  • +334 other locations
A Study of Ladiratuzumab Vedotin in Advanced Solid Tumors

This trial will study ladiratuzumab vedotin (LV) to find out if it works to treat different types of solid tumors. It will also find out what side effects may occur. A side effect is anything the drug does besides treating cancer.

metastasis
human epidermal growth factor
chemoradiotherapy
immunologic adjuvant
solid tumors
FirstHealth of the Carolinas
 (4.5 away) Contact site
  • 12 views
  • 04 Aug, 2021
  • +65 other locations
Platform Trial of Novel Regimens Versus Standard of Care (SoC) in Non-small Cell Lung Cancer (NSCLC)

This study will compare the clinical activity of novel regimens (in combination or as single agents) to standard of care in participants with relapsed/refractory advanced NSCLC. The study will be conducted in two parts; Part 1 is an optional, non-randomized part based on safety and pharmacokinetics/pharmacodynamics (PK/PD) evaluation intended to …

metastasis
docetaxel
cancer chemotherapy
primary cancer
BRAF
GSK Investigational Site
 (4.5 away) Contact site
  • 63 views
  • 22 Jul, 2021
  • +65 other locations
CompassHER2-pCR: Decreasing Chemotherapy for Breast Cancer Patients After Pre-surgery Chemo and Targeted Therapy

This trial studies how well paclitaxel, trastuzumab, and pertuzumab work in eliminating further chemotherapy after surgery in patients with HER2-positive stage II-IIIa breast cancer who have no cancer remaining at surgery (either in the breast or underarm lymph nodes) after pre-operative chemotherapy and HER2-targeted therapy. Drugs used in chemotherapy, such …

core needle biopsy
estrogen receptor
paclitaxel
estrogen
chemotherapy drugs
FirstHealth of the Carolinas-Moore Regional Hospital
 (4.3 away) Contact site
  • 43 views
  • 01 Aug, 2021
  • +576 other locations