Salisbury, North Carolina Clinical Trials

A listing of Salisbury, North Carolina clinical trials actively recruiting patient volunteers.

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Found 36 clinical trials
A Study of Guselkumab in Participants With Active Psoriatic Arthritis

The purpose of this study is to evaluate the efficacy of guselkumab treatment in participants with active psoriatic arthritis (PsA) by assessing the reduction in signs and symptoms of PsA.

peripheral arthritis
arthritis mutilans
biological drug
polyarticular arthritis
DMARD
Klein & Associates, M.D., P.A.
 (312.3 away) Contact site
  • 0 views
  • 18 Jul, 2021
  • +209 other locations
National Adaptive Trial for PTSD Related Insomnia

Many Veterans with posttraumatic stress disorder (PTSD) have trouble sleeping or have frequent nightmares. So far, no medication has been approved for treatment of insomnia in PTSD. The purpose of this research study is to find out if taking medications called trazodone, eszopiclone, or gabapentin can help decrease symptoms of …

gabapentin
wake up
anxiety
depression
trazodone
Durham VA Medical Center, Durham, NC
 (89.7 away) Contact site
  • 10 views
  • 14 Jul, 2021
  • +34 other locations
Study to Evaluate Adverse Events and Change in Disease Activity in Participants Between 18 to 75 Years of Age Treated With Subcutaneous (SC) Injections of ABBV-154 for Moderately to Severely Active Rheumatoid Arthritis (RA)

Rheumatoid Arthritis (RA) is an inflammatory disease of the joints causing pain, stiffness, swelling and loss of joint function. This study evaluates how safe and effective ABBV-154 is in participants treated for moderately to severely active RA. Adverse events and change in the disease activity will be assessed. ABBV-154 is …

antirheumatics
rheumatism
stiffness
methotrexate
PMG Research of Salisbury /ID# 230627
 (3.6 away) Contact site
  • 0 views
  • 04 Aug, 2021
  • +292 other locations
A Study of Erdafitinib Compared With Vinflunine or Docetaxel or Pembrolizumab in Participants With Advanced Urothelial Cancer and Selected Fibroblast Growth Factor Receptor (FGFR) Gene Aberrations

The purpose of this study is to evaluate efficacy of erdafitinib versus chemotherapy or pembrolizumab in participants with advanced urothelial cancer harboring selected fibroblast growth factor receptor (FGFR) aberrations who have progressed after 1 or 2 prior treatments, at least 1 of which includes an anti-programmed death ligand 1(PD-[L]1) agent …

pembrolizumab
erdafitinib
carcinoma
vinflunine
growth factor
Levine Cancer Institute, Carolinas HealthCare System
 (35.5 away) Contact site
  • 271 views
  • 01 Aug, 2021
  • +592 other locations
Changes in NT-proBNP and Outcomes Safety and Tolerability in HFpEF Patients With Acute Decompensated Heart Failure (ADHF) Who Have Been Stabilized During Hospitalization and Initiated In-hospital or Within 30 Days Post-discharge (PARAGLIDE-HF)

The purpose of this study is to assess the effect of sacubitril/valsartan (LCZ696) vs. valsartan on changes in NT-proBNP and outcomes, safety and tolerability in patients with HFpEF (left ventricular ejection fraction (LVEF) > 40%) who have been stabilized during hospitalization for acute decompensated heart failure and initiated in-hospital or …

Novartis Investigative Site
 (3.6 away) Contact site
  • 30 views
  • 08 Jul, 2021
  • +93 other locations
Study to Assess the Efficacy Safety and Tolerability of AVP-786 for the Treatment of Neurobehavioral Disinhibition Including Aggression Agitation and Irritability in Patients With Traumatic Brain Injury

This is a multicenter, randomized, placebo-controlled study to evaluate AVP-786 for the treatment of neurobehavioral disinhibition including aggression, agitation, and irritability in participants with traumatic brain injury (TBI).

Atrium Health - Carolinas Rehabilitation - Charlotte
 (36.6 away) Contact site
  • 3060 views
  • 04 Aug, 2021
  • +83 other locations
Effects of Muscadine Grape Extract in Men With Prostate Cancer on Androgen Deprivation Therapy

It is estimated that one-third of the more than 7 million deaths from cancer worldwide are attributable to potentially modifiable risk factors, with 374,000 deaths preventable through diet modification alone. Diet supplementation for the prevention or treatment of cancer is attractive, as implementation is relatively easy, even in populations with …

cryotherapy
androgen suppression
brachytherapy
definitive treatment
prostate adenocarcinoma
Wake Forest Baptist Medical Center
 (30.3 away) Contact site
  • 16 views
  • 09 Jul, 2021
  • +1 other locations
Vitamin D3 With Chemotherapy and Bevacizumab in Treating Patients With Advanced or Metastatic Colorectal Cancer

This phase III trial studies how well vitamin D3 given with standard chemotherapy and bevacizumab works in treating patients with colorectal cancer that has spread to other parts of the body. Vitamin D3 helps the body use calcium and phosphorus to make strong bones and teeth. Drugs used in chemotherapy, …

solid tumors
metastatic colorectal adenocarcinoma
open biopsy
fluorouracil
monoclonal antibodies
CaroMont Regional Medical Center
 (45.5 away) Contact site
  • 72 views
  • 27 Jul, 2021
  • +978 other locations
Investigation of Rifampin to Reduce Pedal Amputations for Osteomyelitis in Diabetics

The purpose of this research study is to determine if rifampin, an antibiotic (a medicine that treats infections), is effective in treating osteomyelitis (infection of the bone) of the foot in diabetic patients. Despite use of powerful antibiotics prescribed over a long period of time, many diabetic patients remain at …

hypoglycemic agents
diabetes mellitus
glycosylated hemoglobin
hemoglobin a1c
debridement
Salem VA Medical Center, Salem, VA
 (114.8 away) Contact site
  • 513 views
  • 29 Jul, 2021
  • +29 other locations
Efficacy and Safety of TD-1473 in Crohn's Disease

A Phase 2 study to evaluate the efficacy, safety and tolerability of TD-1473 in subjects with moderately-to-severely active Crohn's Disease with up to 48 weeks of treatment.

azathioprine
anti-tnf therapy
corticosteroids
mercaptopurine
ulceration
Theravance Biopharma Investigational Site
 (56.6 away) Contact site
  • 317 views
  • 28 Jan, 2021
  • +208 other locations