Rocky Mount, North Carolina Clinical Trials

A listing of Rocky Mount, North Carolina clinical trials actively recruiting patient volunteers.

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Found 13 clinical trials
A Study of Lirentelimab (AK002) in Patients With Active Eosinophilic Esophagitis

This is a Phase 2/3, multi-center, randomized, double-blind, placebo-controlled study to assess the efficacy and safety of lirentelimab (AK002) given monthly for 6 doses in adult and adolescent patients with active eosinophilic esophagitis. Subjects who complete the randomized, double-blind, placebo-controlled treatment may have the option to receive 6 doses of …

ak002
dysphagia
eosinophil count
hysterectomy
eosinophilia
Allakos Investigational Site
 (6.3 away) Contact site
  • 115 views
  • 22 May, 2021
  • +68 other locations
Effect of Evolocumab in Patients at High Cardiovascular Risk Without Prior Myocardial Infarction or Stroke

This study will assess the effect of lowering low-density lipoprotein cholesterol (LDL-C) with evolocumab on major cardiovascular events in adults without a prior myocardial infarction (MI) or stroke who are at high risk of a cardiovascular event.

infarct
stroke
diabetes
arterial disease
myocardial infarction
Research Site
 (1.7 away) Contact site
  • 536 views
  • 04 Jul, 2021
  • +1332 other locations
Clinical Decision Support to Implement ED-initiated Buprenorphine for OUD

Emergency Departments (EDs) frequently care for individuals with Opioid Use Disorder (OUD). Buprenorphine (BUP) is an effective treatment option for patients with OUD that can safely be initiated in the ED. At present, BUP is rarely initiated as a part of routine ED care. Clinical decision support (CDS) represents a …

Emergency Care Center at Nash General Hospital, UNCHS
 (6.3 away) Contact site
  • 7 views
  • 19 Jun, 2021
  • +22 other locations
A Study of Trastuzumab Deruxtecan (T-DXd) Versus Trastuzumab Emtansine (T-DM1) in High-risk HER2-positive Participants With Residual Invasive Breast Cancer Following Neoadjuvant Therapy (DESTINY-Breast05)

Patients with HER2-positive primary breast cancer (BC) who do not achieve complete response after appropriate neoadjuvant therapy are at higher risk of disease recurrence. More effective treatment options are needed for this patient population. This study will examine the efficacy and safety of trastuzumab deruxtecan (T-DXd) compared with trastuzumab emtansine …

UNC Cancer Care at Nash
 (6.3 away) Contact site
  • 0 views
  • 17 Jul, 2021
  • +425 other locations
A Study to Assess AK002 in Eosinophilic Gastritis and/or Eosinophilic Duodenitis (Formerly Referred to as Eosinophilic Gastroenteritis)

This is a Phase 3, multi-center, randomized, double-blind, placebo-controlled study to assess the efficacy and safety of lirentelimab (AK002), given monthly for 6 doses, in patients with moderately to severely active Eosinophilic Gastritis and/or Eosinophilic Duodenitis (formerly referred to as Eosinophilic Gastroenteritis) who have an inadequate response with, lost response …

Allakos Investigational Site
 (5.8 away) Contact site
  • 59 views
  • 05 Mar, 2021
  • +55 other locations
STUN (STop UNhealthy) Alcohol Use Now! Implementing Evidence-Based Services for Unhealthy Alcohol Use in Primary Care

STUN Alcohol Use Now is an intervention designed to use primary care practice support services (practice facilitation) to help small to medium-size practices (10 or fewer providers) identify and provide services for people with unhealthy alcohol use. 135 primary care practices in North Carolina will be recruited.

Area L AHEC
 (6.3 away) Contact site
  • 133 views
  • 25 Jan, 2021
  • +8 other locations
A Study to Evaluate the Efficacy Safety and Drug Concentration of Certolizumab Pegol (CZP) in Children and Adolescent Study Participants With Moderate to Severe Chronic Plaque Psoriasis (PSO)

The purpose of the study is to demonstrate the efficacy and safety of certolizumab pegol in the treatment of moderate to severe chronic plaque psoriasis in study participants aged 6 to 11 and 12 to 17 years.

Ps0007 50229
 (6.3 away) Contact site
  • 9 views
  • 17 Jun, 2021
  • +46 other locations
A 12-WEEK TITRATE STUDY TO EVALUATE SAFETY TOLERABILITY AND PHARMACODYNAMICS OF PF-06882961 IN ADULTS WITH TYPE 2 DIABETES MELLITUS AND IN NON-DIABETIC ADULTS WITH OBESITY

This study will assess tolerability, safety, and pharmacodynamics (PD) of twice daily (BID) administration of PF- 06882961 in adult participants with Type 2 Diabetes Mellitus (T2DM) who are treated with metformin and in non-diabetic adults with obesity

diabetes
metformin
type 2 diabetes mellitus
a 12
PMG Research of Rocky Mount, LLC - Investigational Product and Mail delivery
 (6.3 away) Contact site
  • 0 views
  • 14 Jun, 2021
  • +40 other locations
Psoriasis Longitudinal Assessment and Registry

The purpose of this study is to further evaluate the safety of infliximab, ustekinumab, and guselkumab in patients with plaque and other forms of psoriasis. The study also includes patients receiving other therapies, such as non-biologic and other biologic agents. The registry also evaluates patient and disease characteristics, including patient-reported …

puva
acitretin
secukinumab
cyclosporine
arthritis
Jeffrey M Suchniak
 (5.8 away) Contact site
  • 4031 views
  • 17 Jul, 2021
  • +491 other locations
HCV-TARGET- Hepatitis C Therapeutic Registry and Research Network

The primary purpose of the HCV-TARGET study is to establish a nationwide registry of patients undergoing treatment with antiviral therapies for chronic hepatitis C (HCV) at both academic and community practices.

chronic hepatitis
telaprevir
boceprevir
antiviral drugs
PMG Research of Rocky Mount, LLC
 (5.8 away) Contact site
  • 1219 views
  • 09 Jul, 2021
  • +49 other locations