Rock Hill, North Carolina Clinical Trials

A listing of Rock Hill, North Carolina clinical trials actively recruiting patient volunteers.

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Found 36 clinical trials
A Dose Finding Efficacy and Safety Study of Ensovibep (MP0420) in Ambulatory Adult Patients With Symptomatic COVID-19

The purpose of this study is to establish the antiviral efficacy of ensovibep against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in humans, identify the optimal dose, and demonstrate its clinical value for treating COVID-19 in adult ambulatory patients

Clinical Research of Rock Hill
 (3.3 away) Contact site
  • 3 views
  • 16 Jul, 2021
  • +44 other locations
Study to Assess the Efficacy Safety and Tolerability of SAR440340/REGN3500/Itepekimab in Chronic Obstructive Pulmonary Disease (COPD)

Primary Objective: Evaluate the efficacy of itepekimab compared with placebo on the annualized rate of acute moderate-or-severe COPD exacerbations in former smokers with moderate-to-severe COPD Secondary Objectives: Evaluate the efficacy of itepekimab compared with placebo on pulmonary function in former smokers with moderate-to-severe COPD Evaluate the efficacy of itepekimab compared …

Investigational Site Number 8400008
 (5.0 away) Contact site
  • 0 views
  • 24 May, 2021
  • +51 other locations
Efficacy and Safety Study of Luspatercept (ACE-536) Versus Epoetin Alfa for the Treatment of Anemia Due to IPSS-R Very Low Low or Intermediate Risk Myelodysplastic Syndromes (MDS) in ESA Na ve Subjects Who Require Red Blood Cell Transfusions

The study will be conducted in compliance with the International Council for Harmonisation (ICH) of Technical Requirements for Registration of Pharmaceuticals for Human Use/Good Clinical Practice (GCP) and applicable regulatory requirements. This is an interventional active-controlled, open-label, randomized Phase 3 study to compare the efficacy and safety of luspatercept (ACE-536) …

anemia
bone marrow procedure
cancer
blood transfusion
erythropoietin
Carolina Blood and Cancer Care
 (3.3 away) Contact site
  • 294 views
  • 29 Aug, 2021
  • +292 other locations
Efficacy and Safety of TD-1473 in Crohn's Disease

A Phase 2 study to evaluate the efficacy, safety and tolerability of TD-1473 in subjects with moderately-to-severely active Crohn's Disease with up to 48 weeks of treatment.

crohn's disease
azathioprine
ulceration
corticosteroids
anti-tnf therapy
Theravance Biopharma Investigational Site
 (3.3 away) Contact site
  • 318 views
  • 08 Sep, 2021
  • +208 other locations
Pivotal Study to Assess the Efficacy Safety and Tolerability of Dupilumab in Patients With Moderate-to-severe COPD With Type 2 Inflammation

Primary Objective: To evaluate the efficacy of dupilumab administered every 2 weeks in patients with moderate-or severe Chronic Obstructive Pulmonary Disease (COPD) as measured by Annualized rate of acute moderate and severe COPD exacerbation (AECOPD) Secondary Objectives: To evaluate the effect of dupilumab administered every 2 weeks on Pre-bronchodilator forced …

forced expiratory volume
muscarinic antagonists
corticosteroids
bronchodilator
pulmonary function test
Investigational Site Number 8400046
 (3.3 away) Contact site
  • 1146 views
  • 14 Jun, 2021
  • +453 other locations
A Study to Test if TEV-53275 is Effective in Relieving Asthma

The primary objective of the study is to evaluate the efficacy of TEV-53275 administered subcutaneously (sc) in adult participants with persistent asthma and an eosinophilic phenotype compared to placebo. A secondary objective is to evaluate the efficacy of TEV-53275 compared to placebo assessed by lung function, asthma symptoms, rescue medication …

Teva Investigational Site 15159
 (5.0 away) Contact site
  • 1 views
  • 12 Sep, 2021
  • +59 other locations
Open-label Study Measuring Safety and Treatment Satisfaction in Adult Subjects With Chronic Immune Thrombocytopenia (ITP) After Switching to Avatrombopag From Eltrombopag or Romiplostim

Evaluate the safety and tolerability of avatrombopag given for 90 days after stopping treatment with eltrombopag or romiplostim.

eltrombopag
thrombocytopenia
romiplostim
avatrombopag
Dova site
 (5.0 away) Contact site
  • 0 views
  • 15 Sep, 2021
  • +3 other locations
A Study of CG-806 in Patients With Relapsed or Refractory CLL/SLL or Non-Hodgkin's Lymphomas

This study is being done to evaluate the safety, tolerability and effectiveness of Oral CG-806 for the treatment of patients with chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), or Non-Hodgkin's Lymphomas who have failed or are intolerant to two or more lines of established therapy or for whom no …

lymphoid leukemia
leukemia
cytopenia
lymphoma
chronic lymphocytic leukemia refractory
Carolina Blood and Cancer Care Associates
 (3.3 away) Contact site
  • 23 views
  • 08 Sep, 2021
  • +34 other locations
S1613 Trastuzumab and Pertuzumab or Cetuximab and Irinotecan Hydrochloride in Treating Patients With Locally Advanced or Metastatic HER2/Neu Amplified Colorectal Cancer That Cannot Be Removed by Surgery

This randomized phase II trial studies how well trastuzumab and pertuzumab work compared to cetuximab and irinotecan hydrochloride in treating patients with HER2/neu amplified colorectal cancer that has spread from where it started to other places in the body and cannot be removed by surgery. Monoclonal antibodies, such as trastuzumab …

serum pregnancy test
oophorectomy
hypertension
absolute neutrophil count
cancer
Levine Cancer Institute-Rock Hill
 (3.3 away) Contact site
  • 419 views
  • 20 May, 2021
  • +829 other locations
EndoPredict Extended Endocrine Trial (EXET)

The purpose of this study is to evaluate the impact of using EndoPredict clinically to inform treatment decisions for extended endocrine therapy, and the subsequent impact on patient outcomes.

breast carcinoma
erbb2
endocrine therapy
invasive breast cancer
HER2
Carolina Blood and Cancer Care Associates
 (3.3 away) Contact site
  • 17 views
  • 28 Aug, 2021
  • +54 other locations