Raleigh, North Carolina Clinical Trials

A listing of Raleigh, North Carolina clinical trials actively recruiting patient volunteers.

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Found 70 clinical trials
Efficacy Evaluation of VERU-111 for mCRPC in Patients Who Have Failed at Least One Androgen Receptor Targeting Agent

To demonstrate the efficacy of VERU-111 (Sabizabulin) in the treatment of metastatic castration-resistant prostate cancer in patients who have failed prior treatment with at least one androgen receptor targeting agent as measured by radiographic progression-free survival.

Associated Urologists of North Carolina
 (6.2 away) Contact site
  • 23 Sep, 2021
  • +42 other locations
Merotocin in Mothers With Inadequate Milk Production and Infants Delivered Prematurely

Induction and support of lactation in women with preterm delivery and inadequate milk production.

Wake Medical Center
 (1.8 away) Contact site
  • 23 Sep, 2021
  • +4 other locations
A Study to Test if TEV-53275 is Effective in Relieving Asthma

The primary objective of the study is to evaluate the efficacy of TEV-53275 administered subcutaneously (sc) in adult participants with persistent asthma and an eosinophilic phenotype compared to placebo. A secondary objective is to evaluate the efficacy of TEV-53275 compared to placebo assessed by lung function, asthma symptoms, rescue medication …

Teva Investigational Site 15168
 (3.7 away) Contact site
  • 22 Sep, 2021
  • +59 other locations
TORUS 2 IDE Clinical Study

The primary objective of the TORUS 2 IDE Clinical Study is to evaluate the safety and effectiveness of the TORUS Stent Graft System in the treatment of obstructive atherosclerotic lesions of the native SFA or the superficial femoral and/or proximal popliteal arteries.

vascular disease
endovascular intervention
NC Heart & Vascular Research
 (3.7 away) Contact site
  • 22 Sep, 2021
  • +33 other locations
Testing The Addition of a New Anti-cancer Drug Venetoclax to the Usual Treatment (Ibrutinib and Obinutuzumab) in Untreated Older Patients With Chronic Lymphocytic Leukemia

This phase III trial compares adding a new anti-cancer drug (venetoclax) to the usual treatment (ibrutinib plus obinutuzumab) in older patients with chronic lymphocytic leukemia who have not received previous treatment. The addition of venetoclax to the usual treatment might prevent chronic lymphocytic leukemia from returning. This trial also will …

night sweats
lymphoid leukemia
flow cytometry
constitutional symptoms
Waverly Hematology Oncology
 (8.4 away) Contact site
  • 22 Sep, 2021
  • +740 other locations
Venous Stent for the Iliofemoral Vein Investigational Clinical Trial Using the DUO Venous Stent System

This is a prospective, multi-center, single-arm, non-blinded clinical trial designed to investigate the safety and efficacy of the Vesper DUO Venous Stent System as compared to a pre-defined performance goal (PG) established from published, peer reviewed scientific literature related to stenting of iliofemoral venous outflow obstructions.

body mass index
blood clot
deep vein thrombosis
NC Heart and Vascular
 (3.7 away) Contact site
  • 23 Sep, 2021
  • +31 other locations
Safety and Efficacy Evaluation of Oxybutynin Topical Gel In Children With Neurogenic Bladder

This study will evaluate the safety and efficacy of Oxybutynin Chloride 10% Topical Gel in children 3 to less than 17 years old, who have overactive bladder due to a neurogenic condition. Children will be treated with 0.75 g of gel/day for two weeks. Patients will then return to the …

neurogenic bladder
overactive bladder
Associated Urologists of North Carolina
 (6.2 away) Contact site
  • 23 Sep, 2021
  • +16 other locations
A Study of an Intratumoral Oncolytic Virus in Patients With Advanced Metastatic Solid Tumors

The purpose of this study is to assess the safety and tolerability of ASP9801 and to determine the recommended phase 2 dose (RP2D). The study will also evaluate antitumor activity, objective response rate, pharmacokinetics and virus shedding of ASP9801.

solid neoplasm
solid tumor
measurable disease
Greenville Health System Cancer Institute
 (1.7 away) Contact site
  • 24 Sep, 2021
  • +19 other locations
MILD Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study

This prospective longitudinal study will compare incidence rates of Medicare beneficiary surgical and minimally invasive intervention post index procedure, as well as harms associated with the MILD procedure, at 24 months post-treatment with MILD, tested against a control group of similar patients that have had a comparable procedure. This study …

Rex Healthcare
 (3.7 away) Contact site
  • 24 Sep, 2021
  • +897 other locations
Personalized Therapy Study - HFRS (TriageHF) Post Approval Study

Medtronic is sponsoring the HFRS PAS to evaluate the HFRS feature (TriageHF) when used in routine clinical practice following commercial release. The HFRS PAS is conducted within Medtronic's Product Surveillance Registry (PSR) platform.

WakeMed Health & Hospitals
 (4.7 away) Contact site
  • 20 Sep, 2021
  • +81 other locations