Raleigh, North Carolina Clinical Trials

A listing of Raleigh, North Carolina clinical trials actively recruiting patient volunteers.

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Found 71 clinical trials
This Study Tests Whether BI 425809 Together With Brain Training Using a Computer Improves Mental Functioning in Patients With Schizophrenia

This is a study in adults with schizophrenia. The study tests whether a medicine called BI 425809 together with brain training improves mental abilities. Participants take study medication once a day for 12 weeks. At the start of the study, the participants are put into 2 groups. It is decided …

cognitive training
anticholinergics
antidepressants
clozapine
antipsychotics
North Carolina Psychiatric Research Center
 (4.7 away) Contact site
  • 773 views
  • 18 Sep, 2021
  • +59 other locations
A Long-term Study to Evaluate Safety and Maintenance of Treatment Effect of LY3074828 in Participants With Moderate-to-Severe Plaque Psoriasis (OASIS-3)

The purpose of this study is to evaluate the long-term safety and maintenance of efficacy of mirikizumab in participants with moderate-to-severe plaque psoriasis.

mirikizumab
plaque psoriasis
PMG Research of Cary, LLC
 (8.4 away) Contact site
  • 717 views
  • 12 Sep, 2021
  • +361 other locations
A Study of TAK-994 in Adults With Type 1 and Type 2 Narcolepsy

The main aims of the study are: To check for side effects from TAK-994 and check what dose of TAK-994 participants can tolerate. To check what dose range provides adequate relief of narcolepsy symptoms. To check how much TAK-994 stays in the blood of participants, over time. The study will …

Raleigh Neurology Associates
 (3.7 away) Contact site
  • 354 views
  • 19 Sep, 2021
  • +115 other locations
Metabolic Interventions to Resolve Non-alcoholic Steatohepatitis (NASH) With Fibrosis (MIRNA)

The study aims to evaluate two, orally administered, investigational agents - PF-06865571 (DGAT2 inhibitor) and the coadministration of PF-06865571 with PF-05221304 (ACC inhibitor). This study is specifically designed to evaluate the effect of a range of doses of DGAT2i alone, and DGAT2i + ACCi, on resolution of NASH or improvement …

fibrosis
hepatic fibrosis
steatohepatitis
M3-Wake Research, Inc.
 (0.6 away) Contact site
  • 72 views
  • 08 Sep, 2021
  • +350 other locations
A Trial to Evaluate the Efficacy and Safety of RSVpreF in Infants Born to Women Vaccinated During Pregnancy.

This randomized, double-blinded, placebo-controlled Phase 3 study is designed to evaluate the efficacy and safety of maternal immunization with RSVpreF against medically attended lower respiratory tract illness (MA-LRTI) in infants.

prenatal
vaccination
lower respiratory tract infection
WakeMed Health & Hospitals
 (1.8 away) Contact site
  • 138 views
  • 19 Sep, 2021
  • +463 other locations
A Study of Trastuzumab Deruxtecan (T-DXd) Versus Trastuzumab Emtansine (T-DM1) in High-risk HER2-positive Participants With Residual Invasive Breast Cancer Following Neoadjuvant Therapy (DESTINY-Breast05)

Patients with HER2-positive primary breast cancer (BC) who do not achieve complete response after appropriate neoadjuvant therapy are at higher risk of disease recurrence. More effective treatment options are needed for this patient population. This study will examine the efficacy and safety of trastuzumab deruxtecan (T-DXd) compared with trastuzumab emtansine …

UNC REX Cancer Center
 (3.7 away) Contact site
  • 1 views
  • 10 Sep, 2021
  • +425 other locations
LIFE-BTK Randomized Controlled Trial

Pre-market clinical evaluation of the everolimus eluting Esprit BTK System for the planned treatment of narrowed infrapopliteal lesions.

NC Heart & Vascular Research
 (3.7 away) Contact site
  • 47 views
  • 18 Sep, 2021
  • +52 other locations
Long-term Safety and Efficacy Study of Lebrikizumab (LY3650150) in Participants With Moderate-to-Severe Atopic Dermatitis (ADjoin)

This 110-week study is designed to assess the long-term safety and efficacy of lebrikizumab for moderate-to-severe atopic dermatitis.

hormonal contraception
progestogen
lebrikizumab
atopy
eczema
Wake Research Associates
 (6.6 away) Contact site
  • 154 views
  • 12 Sep, 2021
  • +357 other locations
Study of Efficacy and Safety of CSJ117 in Patients With Severe Uncontrolled Asthma

The purpose of this study is to determine the efficacy and safety of multiple CSJ117 doses (0.5; 1; 2; 4 and 8 mg) inhaled once daily compared with placebo, when added to standard-of-care (SoC) asthma therapy in adult patients with uncontrolled asthma with respect to change from baseline in FEV1 …

corticosteroids
Novartis Investigative Site
 (3.7 away) Contact site
  • 48 views
  • 19 Sep, 2021
  • +143 other locations
A Study to Test if Fremanezumab is Effective in Preventing Migraine in Children and Adolescents

The primary objective of the study is to evaluate the long-term safety and tolerability of subcutaneous fremanezumab in the preventive treatment of migraine in pediatric participants 6 to 17 years of age (inclusive at enrollment in the pivotal study). Secondary objectives are to evaluate the efficacy of subcutaneous fremanezumab in …

body mass index
headache
preventive medication
migraine in children
Teva Investigational Site 14248
 (3.7 away) Contact site
  • 0 views
  • 19 Sep, 2021
  • +33 other locations