Raleigh, North Carolina Clinical Trials

A listing of Raleigh, North Carolina clinical trials actively recruiting patient volunteers.

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Found 71 clinical trials
A Study to Test if Fremanezumab is Effective in Preventing Chronic Migraine in Patients 6 to 17 Years of Age

The primary objective of the study is to evaluate the effectiveness of fremanezumab as compared to placebo for the preventive treatment of chronic migraine (CM). Secondary objectives are to further demonstrate the efficacy of Fremanezumab as compared to placebo for the preventive treatment of CM, to evaluate the safety and …

chronic migraine
daily headaches
recurrent headaches
headache
fremanezumab
Teva Investigational Site 14248
 (3.7 away) Contact site
  • 0 views
  • 24 Sep, 2021
  • +69 other locations
A Study to Test if Fremanezumab is Effective in Preventing Episodic Migraine in Patients 6 to 17 Years of Age

The primary objective of the study is to evaluate the effectiveness of fremanezumab as compared to placebo for the preventive treatment of episodic migraine (EM). Secondary objectives are to further demonstrate the efficacy of Fremanezumab as compared to placebo for the preventive treatment of EM, to evaluate the safety and …

daily headaches
episodic migraine
recurrent headaches
headache
fremanezumab
Teva Investigational Site 14248
 (3.7 away) Contact site
  • 51 views
  • 26 Sep, 2021
  • +69 other locations
LIFE-BTK Randomized Controlled Trial

Pre-market clinical evaluation of the everolimus eluting Esprit BTK System for the planned treatment of narrowed infrapopliteal lesions.

NC Heart & Vascular Research
 (3.7 away) Contact site
  • 47 views
  • 18 Sep, 2021
  • +52 other locations
Oregovomab Plus Chemo in Newly Diagnosed Patients With Advanced Epithelial Ovarian Cancer Following Optimal Debulking Surgery

Study to compare the safety and efficacy of oregovomab versus placebo, administered in combination with specific cycles of a standard six-cycle chemotherapy regimen (paclitaxel and carboplatin), for the treatment of subjects with newly diagnosed advanced ovarian cancer who have undergone optimal debulking.

renal function tests
serous cystadenocarcinoma
debulking surgery
chemotherapy regimen
paclitaxel
Duke Women's Cancer Care Raleigh
 (3.7 away) Contact site
  • 26 views
  • 20 Sep, 2021
  • +94 other locations
Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors Lymphomas or Multiple Myeloma (The MATCH Screening Trial)

This phase II MATCH trial studies how well treatment that is directed by genetic testing works in patients with solid tumors or lymphomas that have progressed following at least one line of standard treatment or for which no agreed upon treatment approach exists. Genetic tests look at the unique genetic …

multiple myeloma
antiretrovirals
chemotherapy regimen
tumor cells
treatment regimen
Waverly Hematology Oncology
 (8.4 away) Contact site
  • 6097 views
  • 26 Sep, 2021
  • +1027 other locations
A Study of Pembrolizumab (MK-3475) With or Without Maintenance Olaparib in First-line Metastatic Squamous Non-small Cell Lung Cancer (NSCLC MK-7339-008/KEYLYNK-008)

The current study will compare pembrolizumab (MK-3475) plus maintenance olaparib, vs. pembrolizumab plus maintenance olaparib placebo for the treatment of squamous NSCLC. The study's 2 primary hypotheses are: Pembrolizumab plus maintenance olaparib is superior to pembrolizumab plus maintenance olaparib placebo with respect to progression-free survival (PFS) per RECIST 1.1 by …

Waverly Hematology Oncology ( Site 0054)
 (8.5 away) Contact site
  • 119 views
  • 26 Sep, 2021
  • +202 other locations
A Study to Evaluate the Safety and Efficacy of MEDI8897 for the Prevention of Medically Attended RSV LRTI in Healthy Late Preterm and Term Infants

The purpose of this study is to evaluate the efficacy, safety, pharmacokinetics (PK), and antidrug antibody (ADA) response for MEDI8897 in healthy late preterm and term infants who are 35 weeks or greater gestational age and entering their first RSV season.

Research Site
 (5.2 away) Contact site
  • 580 views
  • 26 Sep, 2021
  • +414 other locations
A Study of Guselkumab in Participants With Moderately to Severely Active Ulcerative Colitis

The purpose of this study is to evaluate the efficacy and safety of guselkumab in participants with moderately to severely active ulcerative colitis (UC).

medical therapy
Duke University Hospital Medical Center
 (5.2 away) Contact site
  • 227 views
  • 12 Sep, 2021
  • +535 other locations
Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG

The primary objective of this study is to evaluate the effectiveness (prevention of thromboembolic events) and safety (major bleeding) of adding oral anticoagulation (OAC) to background antiplatelet therapy in patients who develop new-onset post-operative atrial fibrillation (POAF) after isolated coronary artery bypass graft (CABG) surgery. All patients with a qualifying …

coronary artery bypass graft
fibrillation
antiplatelet therapy
clopidogrel
atrial fibrillation
WakeMed
 (1.8 away) Contact site
  • 112 views
  • 23 Sep, 2021
  • +79 other locations
A Study to Evaluate the Effect of Testosterone Replacement Therapy (TRT) on the Incidence of Major Adverse Cardiovascular Events (MACE) and Efficacy Measures in Hypogonadal Men

This is a blinded and placebo-controlled study of topical testosterone replacement therapy (TRT) in symptomatic hypogonadal men with increased risk for cardiovascular (CV) disease.

replacement therapy
testosterone
testosterone level
serum testosterone
testosterone topical
Family Medical Associates of Raleigh /ID# 203979
 (4.7 away) Contact site
  • 16902 views
  • 26 Sep, 2021
  • +495 other locations