Raleigh, North Carolina Clinical Trials

A listing of Raleigh, North Carolina clinical trials actively recruiting patient volunteers.

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Found 71 clinical trials
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The RADIANCE II Pivotal Study: A Study of the ReCor Medical Paradise System in Stage II Hypertension

The objective of the RADIANCE II Pivotal study is to demonstrate the effectiveness and safety of the Paradise System in subjects with Stage 2 hypertension on 0-2 medications at the time of consent. Prior to randomization, subjects will be hypertensive in the absence of hypertension medication.

antihypertensive drugs
hypertension
hypertensive medication
renal angiogram
angiography
WakeMed Raleigh
 (1.8 away) Contact site
  • 877 views
  • 01 Aug, 2021
  • +82 other locations
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C2541013 MIRNA NASH  

The study aims to evaluate two, orally administered, investigational agents - PF-06865571 (DGAT2 inhibitor) and the coadministration of PF-06865571 with PF-05221304 (ACC inhibitor). This study is specifically designed to evaluate the effect of a range of doses of DGAT2i alone, and DGAT2i + ACCi, on resolution of NASH or improvement …

M3 Wake Research Associates
 (6.6 away)
  • 275 views
  • 30 Jul, 2021
  • +64 other locations
COVID-19 Thrombosis Prevention Trials: Post-hospital Thromboprophylaxis

A multicenter, adaptive, randomized platform trial evaluating the efficacy and safety of antithrombotic strategies in patients with COVID-19 following hospital discharge

Wake Med Hospital
 (4.7 away) Contact site
  • 0 views
  • 04 Aug, 2021
  • +74 other locations
Establishing the Safety and Efficacy of Reloxaliase in Patients With Enteric Hyperoxaluria

The purpose of this study is to determine the efficacy, durability and long-term safety of reloxaliase in patients with enteric hyperoxaluria.

Associated Urologists of North Carolina
 (6.2 away) Contact site
  • 7 views
  • 04 Aug, 2021
  • +83 other locations
Long-term Safety and Efficacy of Nemolizumab With Moderate-to-severe Atopic Dermatitis

Long-Term Safety and Efficacy of Nemolizumab in Subjects with Moderate-to-Severe Atopic Dermatitis Description

Galderma Investigational Site
 (6.2 away) Contact site
  • 21 views
  • 04 Aug, 2021
  • +470 other locations
Efficacy Safety and Tolerability of Atogepant for the Prevention of Chronic Migraine

This study will evaluate the efficacy, safety and tolerability of atogepant in participants with chronic migraine. This study includes a 12-week treatment period.

migraine
headache
Raleigh Neurology Associates, P.A
 (3.7 away) Contact site
  • 576 views
  • 24 Jul, 2021
  • +178 other locations
Fixed-Dose Trial in Early Parkinson's Disease (TemPo-1)

The purpose of this study is to evaluate the clinical efficacy, safety and pharmacokinetics (PK) of 2 fixed doses of tavapadon and placebo in participants with early Parkinson's Disease.

mao-b inhibitor
dopamine
essential tremor
parkinsonism
tremor
Raleigh Neurology Associates
 (3.7 away) Contact site
  • 0 views
  • 31 Jul, 2021
  • +76 other locations
Study of Evobrutinib in Participants With RMS (evolutionRMS 2)

The study is to evaluate the efficacy and safety of evobrutinib administered orally twice daily versus Teriflunomide (Aubagio), administered orally once daily in participants with Relapsing Multiple Sclerosis (RMS).

aubagio
evobrutinib
teriflunomide
Research Site 730
 (3.7 away) Contact site
  • 0 views
  • 31 Jul, 2021
  • +258 other locations
Study of a Recombinant Coronavirus-Like Particle COVID-19 Vaccine in Adults

This Phase 2/3 study is a multi-portion design to confirm that the chosen formulation and dosing regimen of CoVLP has an acceptable immunogenicity and safety profile. The Phase 3 portion is an event-driven, randomized, observer blinded, placebo-controlled design that will evaluate the efficacy and safety of the CoVLP formulation compared …

M3 Wake Research, Inc
 (6.2 away) Contact site
  • 0 views
  • 01 Aug, 2021
  • +85 other locations
A Study to Test if Fremanezumab is Effective in Preventing Migraine in Children and Adolescents

The primary objective of the study is to evaluate the long-term safety and tolerability of subcutaneous fremanezumab in the preventive treatment of migraine in pediatric participants 6 to 17 years of age (inclusive at enrollment in the pivotal study). Secondary objectives are to evaluate the efficacy of subcutaneous fremanezumab in …

body mass index
migraine in children
headache
preventive medication
Teva Investigational Site 14248
 (3.7 away) Contact site
  • 0 views
  • 29 Jul, 2021
  • +26 other locations