Pinehurst, North Carolina Clinical Trials

A listing of Pinehurst, North Carolina clinical trials actively recruiting patient volunteers.

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Found 52 clinical trials
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A Randomized, Open Label Study Comparing the Combination of YONDELIS® and DOXIL®/CAELYX® with DOXIL®/CAELYX® Monotherapy for the Treatment of Advanced-Relapsed Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

A Randomized, Open Label Study Comparing the Combination of YONDELIS® and DOXIL®/CAELYX® with DOXIL®/CAELYX® Monotherapy for the Treatment of Advanced-Relapsed Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

First Health Outpatient Cancer Center
 (1.7 away) Contact site
  • 644 views
  • 08 Nov, 2020
  • +4 other locations
featured
A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients With Advanced Solid Tumors With KRAS G12C Mutation

Evaluates the safety, tolerability, pharmacokinetics, metabolites, pharmacodynamics, and clinical activity of MRTX849 in patients with advanced solid tumors with a KRAS G12C mutation. MRTX849 is an orally-available small molecule inhibitor of KRAS G12C.

malignant solid tumor
advanced solid tumor
solid tumor
Mirati Research Site
 (1.8 away) Contact site
  • 405 views
  • 08 Jul, 2021
  • +72 other locations
Vitamin D3 With Chemotherapy and Bevacizumab in Treating Patients With Advanced or Metastatic Colorectal Cancer

This phase III trial studies how well vitamin D3 given with standard chemotherapy and bevacizumab works in treating patients with colorectal cancer that has spread to other parts of the body. Vitamin D3 helps the body use calcium and phosphorus to make strong bones and teeth. Drugs used in chemotherapy, …

liver metastasis
cancer
bevacizumab
cancer treatment
measurable disease
FirstHealth of the Carolinas-Moore Regional Hospital
 (2.2 away) Contact site
  • 65 views
  • 27 Jul, 2021
  • +978 other locations
Daratumumab Pomalidomide and Dexamethasone in Treating Patients With Relapsed Multiple Myeloma

This phase II trial studies how well daratumumab, pomalidomide, and dexamethasone work in treating patients with multiple myeloma that has come back (relapsed). Immunotherapy with daratumumab may induce changes in body's immune system and may interfere with the ability of cancer cells to grow and spread. Drugs used in chemotherapy, …

bortezomib
cancer
electrophoresis
lenalidomide
neutrophil count
FirstHealth of the Carolinas-Moore Regional Hospital
 (0.9 away) Contact site
  • 0 views
  • 16 Apr, 2021
  • +9 other locations
Efficacy and Safety of APP13007 for Treatment of Inflammation and Pain After Cataract Surgery

This Phase 3 study will evaluate APP13007 in comparison to the matching vehicle placebo in a randomized, parallel-group, double-masked fashion. The subjects will have undergone routine cataract surgery on Day 0 of the study and will be assessed the next day (Post-operative Day 1; POD1) after uncomplicated surgery for eligibility …

Carolina Eye Associates
 (4.5 away) Contact site
  • 0 views
  • 28 Jul, 2021
  • +31 other locations
Study of AVB-S6-500 in Combination With Paclitaxel vs Paclitaxel in Patients With Platinum-Resistant Recurrent Ovarian Cancer

This is a Phase 3 study of AVB-S6-500 in combination with paclitaxel (Pac) in patients with platinum resistant recurrent ovarian cancer. This is a randomized, double-blind, placebo-controlled study to compare efficacy and tolerability of AVB-S6-500 in combination with Pac versus placebo plus Pac.

First Health of the Carolinas
 (2.2 away) Contact site
  • 0 views
  • 04 Jul, 2021
  • +27 other locations
Clinical Trial of Neoadjuvant Chemotherapy With Atezolizumab or Placebo in Patients With Triple-Negative Breast Cancer Followed After Surgery by Atezolizumab or Placebo

The main purpose of this study is to learn if the usual chemotherapy given before surgery (neoadjuvant therapy) for breast cancer plus the experimental drug, atezolizumab, is better than the usual chemotherapy plus a placebo. (A placebo is a drug that looks like the study drug but contains no medication.) …

adenocarcinoma
core needle biopsy
mammogram
paclitaxel
cancer
FirstHealth of the Carolinas FirstHealth Outpatient Cancer Center
 (2.2 away) Contact site
  • 1000 views
  • 21 Apr, 2021
  • +234 other locations
Doxorubicin Hydrochloride and Cyclophosphamide Followed by Paclitaxel With or Without Carboplatin in Treating Patients With Triple-Negative Breast Cancer

This randomized phase III trial studies how well doxorubicin hydrochloride and cyclophosphamide followed by paclitaxel with or without carboplatin work in treating patients with triple-negative breast cancer. Drugs used in chemotherapy, such as doxorubicin hydrochloride, cyclophosphamide, paclitaxel, and carboplatin, work in different ways to stop the growth of tumor cells, …

adenocarcinoma
estrogen
immunohistochemistry
paclitaxel
breast adenocarcinoma
FirstHealth of the Carolinas-Moore Regional Hospital
 (2.2 away) Contact site
  • 814 views
  • 24 Jan, 2021
  • +810 other locations
Women's IschemiA TRial to Reduce Events In Non-ObstRuctive CAD

The Ischemia-IMT (Ischemia-Intensive Medical Treatment Reduces Events in Women with Non-Obstructive CAD), subtitle: Women's Ischemia Trial to Reduce Events in Non-Obstructive CAD (WARRIOR) trial is a multicenter, prospective, randomized, blinded outcome evaluation (PROBE design) evaluating intensive statin/ACE-I (or ARB)/aspirin treatment (IMT) vs. usual care (UC) in 4,422 symptomatic women patients …

angina pectoris
atorvastatin
rosuvastatin
aspirin
myocardial infarction
Pinehurst Medical Clinic
 (1.7 away) Contact site
  • 492 views
  • 03 Feb, 2021
  • +70 other locations
Genetic Testing in Screening Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been or Will Be Removed by Surgery (The ALCHEMIST Screening Trial)

This ALCHEMIST trial studies genetic testing in screening patients with stage IB-IIIA non-small cell lung cancer that has been or will be removed by surgery. Studying the genes in a patient's tumor cells may help doctors select the best treatment for patients that have certain genetic changes.

adenocarcinoma
erlotinib
pembrolizumab
gemcitabine
cancer
FirstHealth of the Carolinas-Moore Regional Hospital
 (2.2 away) Contact site
  • 1103 views
  • 31 Jul, 2021
  • +1138 other locations