North Wilkesboro, North Carolina Clinical Trials

A listing of North Wilkesboro, North Carolina clinical trials actively recruiting patient volunteers.

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Found 18 clinical trials
A Clinical Study Evaluating The Benefit of Adding Rucaparib to Enzalutamide for Men With Metastatic Prostate Cancer That Has Become Resistant To Testosterone-Deprivation Therapy

This randomized, placebo-controlled phase III trial is evaluating the benefit of rucaparib and enzalutamide combination therapy versus enzalutamide alone for the treatment of men with prostate cancer that has spread to other places in the body (metastatic) and has become resistant to testosterone-deprivation therapy (castration-resistant). Enzalutamide helps fight prostate cancer …

Wake Forest Baptist Health - Wilkes Medical Center
 (9.0 away) Contact site
  • 0 views
  • 31 Jul, 2021
  • +251 other locations
Comparison of Axillary Lymph Node Dissection With Axillary Radiation for Patients With Node-Positive Breast Cancer Treated With Chemotherapy

This randomized phase III trial studies lymph node dissection and radiation therapy to see how well it works compared to radiation therapy alone in treating patients with breast cancer previously treated with chemotherapy and surgery. Lymph node dissection may remove cancer cells that have spread to nearby lymph nodes in …

anthracyclines
axillary lymph node dissection
tumor cells
carcinoma in situ
skin carcinoma
Novant Health Cancer Institute - Wilkesboro
 (9.0 away) Contact site
  • 476 views
  • 22 Jun, 2021
  • +741 other locations
Testing Immunotherapy Versus Observation in Patients With HPV Throat Cancer

This phase II/III trials studies whether maintenance immunotherapy (nivolumab) following definitive treatment with radiation and chemotherapy (cisplatin) result in significant improvement in overall survival (time being alive) and progression-free survival (time being alive without cancer) for patients with intermediate risk human papillomavirus (HPV) positive oropharynx cancer (throat cancer) that has …

Novant Health Oncology Specialists-Wilkesboro
 (5.2 away) Contact site
  • 135 views
  • 04 Aug, 2021
  • +539 other locations
Immunotherapy (Nivolumab or Brentuximab Vedotin) Plus Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage III-IV Classic Hodgkin Lymphoma

This phase III trial compares immunotherapy drugs (nivolumab or brentuximab vedotin) when given with combination chemotherapy in treating patients with newly diagnosed stage III or IV classic Hodgkin lymphoma. Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's immune system attack the cancer, and may interfere with the …

prednisone
cancer
tumor cells
hepatitis
human immunodeficiency virus
Novant Health Oncology Specialists-Wilkesboro
 (9.0 away) Contact site
  • 68 views
  • 04 Aug, 2021
  • +507 other locations
Chemoradiation With or Without Atezolizumab in Treating Patients With Limited Stage Small Cell Lung Cancer

This phase III trial studies how well chemotherapy and radiation therapy (chemoradiation) with or without atezolizumab works in treating patients with limited stage small cell lung cancer. Drugs used in chemotherapy, such as etoposide, cisplatin, and carboplatin, work in different ways to stop the growth of tumor cells, either by …

Novant Health Oncology Specialists-Wilkesboro
 (5.2 away) Contact site
  • 85 views
  • 04 Aug, 2021
  • +334 other locations
Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

This screening and multi-sub-study randomized phase II/III trial will establish a method for genomic screening of similar large cancer populations followed by assigning and accruing simultaneously to a multi-sub-study hybrid Master Protocol (Lung-MAP). The type of cancer trait (biomarker) will determine to which sub-study, within this protocol, a participant will …

Novant Health Oncology Specialists-Wilkesboro
 (5.2 away) Contact site
  • 193 views
  • 10 May, 2021
  • +876 other locations
Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With Cabozantinib for Patients With Advanced Kidney Cancer The PDIGREE Study

This phase III trial compares the usual treatment (treatment with ipilimumab and nivolumab followed by nivolumab alone) to treatment with ipilimumab and nivolumab, followed by nivolumab with cabozantinib in patients with untreated renal cell carcinoma that has spread to other parts of the body. The addition of cabozantinib to the …

cancer
tumor cells
il-2
liver metastasis
nephrectomy
Novant Health Oncology Specialists-Wilkesboro
 (5.2 away) Contact site
  • 157 views
  • 04 Aug, 2021
  • +680 other locations
CompassHER2-pCR: Decreasing Chemotherapy for Breast Cancer Patients After Pre-surgery Chemo and Targeted Therapy

This trial studies how well paclitaxel, trastuzumab, and pertuzumab work in eliminating further chemotherapy after surgery in patients with HER2-positive stage II-IIIa breast cancer who have no cancer remaining at surgery (either in the breast or underarm lymph nodes) after pre-operative chemotherapy and HER2-targeted therapy. Drugs used in chemotherapy, such …

hepatitis c virus
core needle biopsy
chronic hepatitis b
tumor cells
carcinoma in situ
Novant Health Oncology Specialists-Wilkesboro
 (5.2 away) Contact site
  • 43 views
  • 01 Aug, 2021
  • +576 other locations
Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors Lymphomas or Multiple Myeloma (The MATCH Screening Trial)

This phase II MATCH trial studies how well treatment that is directed by genetic testing works in patients with solid tumors or lymphomas that have progressed following at least one line of standard treatment or for which no agreed upon treatment approach exists. Genetic tests look at the unique genetic …

cytology specimen collection procedure
potassium
human immunodeficiency virus
liver metastasis
adavosertib
Novant Health Oncology Specialists-Wilkesboro
 (5.2 away) Contact site
  • 6088 views
  • 04 Aug, 2021
  • +1020 other locations
BLAST MRD AML-1: BLockade of PD-1 Added to Standard Therapy to Target Measurable Residual Disease in Acute Myeloid Leukemia 1- A Randomized Phase 2 Study of Anti-PD-1 Pembrolizumab in Combination With Intensive Chemotherapy as Frontline Therapy in Patients With Acute Myeloid Leukemia

This phase II trial studies how well cytarabine and idarubicin or daunorubicin with or without pembrolizumab work in treating patients with newly-diagnosed acute myeloid leukemia. Drugs used in chemotherapy, such as cytarabine, idarubicin, and daunorubicin, work in different ways to stop the growth of cancer cells, either by killing the …

leukapheresis
induction chemotherapy
cancer
chronic myelomonocytic leukemia
lenalidomide
Wake Forest Baptist Health - Wilkes Medical Center
 (9.0 away) Contact site
  • 0 views
  • 23 Jul, 2021
  • +8 other locations