New Bern, North Carolina Clinical Trials

A listing of New Bern, North Carolina clinical trials actively recruiting patient volunteers.

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Found 33 clinical trials
Dapagliflozin in PRESERVED Ejection Fraction Heart Failure

The primary purpose of this study is to evaluate the impact of dapagliflozin, as compared with placebo, on heart failure, disease specific biomarkers, symptoms, health status and quality of life in patients with chronic heart failure with preserved systolic function.

Eastern Nephrology Associates
 (6.8 away) Contact site
  • 69 views
  • 13 May, 2021
  • +25 other locations
Olanzapine With or Without Fosaprepitant Dimeglumine in Preventing Chemotherapy Induced Nausea and Vomiting in Cancer Patients Receiving Highly Emetogenic Chemotherapy

This randomized phase III trial studies how well olanzapine with or without fosaprepitant work in preventing chemotherapy induced nausea and vomiting in cancer patients receiving chemotherapy that causes vomiting. Olanzapine and fosaprepitant dimeglumine may help control nausea and vomiting in patients during chemotherapy. Olanzapine is usually given in combination with …

vomiting
metastasis
diabetes
cyclophosphamide
treatment regimen
CarolinaEast Medical Center
 (5.3 away) Contact site
  • 109 views
  • 29 Jul, 2021
  • +603 other locations
A Study to Evaluate the Safety and Efficacy of Upadacitinib in Participants With Giant Cell Arteritis

This study consists of two periods. The objective of Period 1 is to evaluate the efficacy of upadacitinib in combination with a 26-week corticosteroid (CS) taper regimen compared to placebo in combination with a 52-week CS taper regimen, as measured by the proportion of participants in sustained remission at Week …

Coastal Carolina Health Care /ID# 212430
 (6.8 away) Contact site
  • 311 views
  • 01 Aug, 2021
  • +302 other locations
Efficacy and Safety of Benralizumab in Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD) With a History of Frequent Exacerbations

Phase 3 study to evaluate the efficacy and safety of a benralizumab in patients with moderate to very severe COPD with a history of frequent COPD exacerbations and elevated peripheral blood eosinophils (300/L). Eligible patients must have a history of 2 moderate and/or severe COPD exacerbations in the previous year …

eosinophil count
antibiotics
severe chronic obstructive pulmonary disease
bronchodilator
corticosteroids
Research Site
 (6.8 away) Contact site
  • 838 views
  • 04 Aug, 2021
  • +426 other locations
Benralizumab Airway Remodeling Study in Severe Eosinophilic Asthmatics

The purpose of the study is to evaluate effect of benralizumab on structural and lung function changes in severe eosinophilic asthmatics. Changes will be assessed over 48 week treatment period in patients with persistent symptoms despite standard therapy of inhaled corticosteroids (ICS) plus long acting B2-agonist (LABA) with or without …

eosinophil count
fluticasone
pulmonary function test
benralizumab
corticosteroids
Research Site
 (6.8 away) Contact site
  • 119 views
  • 14 Jul, 2021
  • +47 other locations
Tezepelumab COPD Exacerbation Study

A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel Group, Phase 2a Study to Explore the Efficacy and Safety of Tezepelumab in Adults with Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD)

copd exacerbation
severe chronic obstructive pulmonary disease
ct scan
bronchodilator
Research Site
 (6.8 away) Contact site
  • 130 views
  • 23 Jul, 2021
  • +107 other locations
SWOG S1827 (MAVERICK) Testing Whether the Use of Brain Scans Alone Instead of Brain Scans Plus Preventive Brain Radiation Affects Lifespan in Patients With Small Cell Lung Cancer

This phase III trial studies magnetic resonance imaging (MRI) surveillance and prophylactic cranial irradiation (PCI) to see how well they work compared to MRI surveillance alone in treating patients with small cell lung cancer. MRI scans are used to monitor the possible spread of the cancer with an MRI machine …

cancer
tubal ligation
brain metastases
ct scan
oophorectomy
CarolinaEast Medical Center
 (5.3 away) Contact site
  • 34 views
  • 20 Jul, 2021
  • +131 other locations
Testing the Addition of an Antibody to Standard Chemoradiation Followed by the Antibody for One Year to Standard Chemoradiation Followed by One Year of the Antibody in Patients With Unresectable Stage III Non-Small Cell Lung Cancer

This phase III trial studies how well an antibody (durvalumab) with chemotherapy and radiation therapy (chemoradiation) works in treating patients with stage III non-small cell lung cancer that cannot be removed by surgery (unresectable). Immunotherapy with monoclonal antibodies, such as durvalumab, may help the body's immune system attack the cancer, …

tubal ligation
tumor cells
alopecia
platelet count
lung cancer
Vidant Oncology-Kinston
 (35.0 away) Contact site
  • 136 views
  • 04 Aug, 2021
  • +584 other locations
Pivotal Study to Assess the Efficacy Safety and Tolerability of Dupilumab in Patients With Moderate to Severe COPD With Type 2 Inflammation

Primary Objective: To evaluate the efficacy of dupilumab administered every 2 weeks in patients with moderate or severe Chronic Obstructive Pulmonary Disease (COPD) as measured by Annualized rate of acute moderate or severe COPD exacerbation (AECOPD) Secondary Objectives: To evaluate the effect of dupilumab administered every 2 weeks on Pre-bronchodilator …

bronchitis
bronchodilator
eosinophil count
copd exacerbation
severe chronic obstructive pulmonary disease
Investigational Site Number 8400025
 (3.5 away) Contact site
  • 156 views
  • 18 Jul, 2021
  • +217 other locations
Study Of Oral Elagolix Tablets In Combination With Combined Oral Contraceptive Capsules/Tablets To Assess Dysmenorrhea Response In Adult Female Participants With Endometriosis And Associated Moderate To Severe Pain

Endometriosis is a painful disorder of the uterus affecting 6-10% of women of childbearing age. Endometriosis affects daily activities, social relationships, sexuality and sexual activity, and mental health. This study will evaluate how well elagolix in combination with combined oral contraceptives (COC) works within the body and/or how safe it …

combined oral contraceptives
endometriosis
elagolix
dysmenorrhea
Eastern Carolina Women's Centr /ID# 222358
 (3.5 away) Contact site
  • 396 views
  • 26 Jul, 2021
  • +202 other locations