Mt. Airy, North Carolina Clinical Trials

A listing of Mt. Airy, North Carolina clinical trials actively recruiting patient volunteers.

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Found 12 clinical trials
Intramuscular VIR-7831 (Sotrovimab) for Mild/Moderate COVID-19

A Phase 3 randomized, multi-center, open label study to assess the efficacy, safety, and tolerability of monoclonal antibody VIR-7831 (sotrovimab) given intramuscularly versus intravenously for the treatment of mild/moderate coronavirus disease 2019 (COVID-19) in high-risk non-hospitalized patients

Investigative Site
 (48.2 away) Contact site
  • 0 views
  • 01 Aug, 2021
  • +66 other locations
A Study to Evaluate Dostarlimab Plus Carboplatin-paclitaxel Versus Placebo Plus Carboplatin-paclitaxel in Participants With Recurrent or Primary Advanced Endometrial Cancer

This is a 2 part study. Part 1 is to evaluate the efficacy and safety of dostarlimab plus carboplatin-paclitaxel followed by dostarlimab versus placebo plus carboplatin-paclitaxel followed by placebo; and Part 2 is to evaluate the efficacy and safety of dostarlimab plus carboplatin-paclitaxel followed by dostarlimab plus niraparib versus placebo …

liver metastasis
metastasis
paclitaxel
anticoagulant
direct bilirubin
GSK Investigational Site
 (34.1 away) Contact site
  • 78 views
  • 01 Aug, 2021
  • +154 other locations
Testing Immunotherapy Versus Observation in Patients With HPV Throat Cancer

This phase II/III trials studies whether maintenance immunotherapy (nivolumab) following definitive treatment with radiation and chemotherapy (cisplatin) result in significant improvement in overall survival (time being alive) and progression-free survival (time being alive without cancer) for patients with intermediate risk human papillomavirus (HPV) positive oropharynx cancer (throat cancer) that has …

Novant Health Oncology Specialists-Mount Airy
 (0.3 away) Contact site
  • 135 views
  • 04 Aug, 2021
  • +539 other locations
Immunotherapy (Nivolumab or Brentuximab Vedotin) Plus Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage III-IV Classic Hodgkin Lymphoma

This phase III trial compares immunotherapy drugs (nivolumab or brentuximab vedotin) when given with combination chemotherapy in treating patients with newly diagnosed stage III or IV classic Hodgkin lymphoma. Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's immune system attack the cancer, and may interfere with the …

dacarbazine
monoclonal antibodies
alopecia
cell transplantation
mixed cellularity hodgkin lymphoma
Novant Health Forsyth Medical Center
 (34.1 away) Contact site
  • 68 views
  • 04 Aug, 2021
  • +507 other locations
Chemoradiation With or Without Atezolizumab in Treating Patients With Limited Stage Small Cell Lung Cancer

This phase III trial studies how well chemotherapy and radiation therapy (chemoradiation) with or without atezolizumab works in treating patients with limited stage small cell lung cancer. Drugs used in chemotherapy, such as etoposide, cisplatin, and carboplatin, work in different ways to stop the growth of tumor cells, either by …

Novant Health Oncology Specialists-Mount Airy
 (0.3 away) Contact site
  • 85 views
  • 04 Aug, 2021
  • +334 other locations
Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With Cabozantinib for Patients With Advanced Kidney Cancer The PDIGREE Study

This phase III trial compares the usual treatment (treatment with ipilimumab and nivolumab followed by nivolumab alone) to treatment with ipilimumab and nivolumab, followed by nivolumab with cabozantinib in patients with untreated renal cell carcinoma that has spread to other parts of the body. The addition of cabozantinib to the …

liver metastasis
sunitinib
metastasis
il-2
calcium
Novant Health Oncology Specialists-Mount Airy
 (0.3 away) Contact site
  • 157 views
  • 04 Aug, 2021
  • +680 other locations
CompassHER2-pCR: Decreasing Chemotherapy for Breast Cancer Patients After Pre-surgery Chemo and Targeted Therapy

This trial studies how well paclitaxel, trastuzumab, and pertuzumab work in eliminating further chemotherapy after surgery in patients with HER2-positive stage II-IIIa breast cancer who have no cancer remaining at surgery (either in the breast or underarm lymph nodes) after pre-operative chemotherapy and HER2-targeted therapy. Drugs used in chemotherapy, such …

core needle biopsy
estrogen receptor
paclitaxel
estrogen
chemotherapy drugs
Novant Health Oncology Specialists-Mount Airy
 (0.3 away) Contact site
  • 43 views
  • 01 Aug, 2021
  • +576 other locations
Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors Lymphomas or Multiple Myeloma (The MATCH Screening Trial)

This phase II MATCH trial studies how well treatment that is directed by genetic testing works in patients with solid tumors or lymphomas that have progressed following at least one line of standard treatment or for which no agreed upon treatment approach exists. Genetic tests look at the unique genetic …

liver metastasis
cancer treatment
platelet count
alopecia
serum pregnancy test
Novant Health Oncology Specialists-Mount Airy
 (0.3 away) Contact site
  • 6088 views
  • 04 Aug, 2021
  • +1020 other locations
Pegylated Liposomal Doxorubicin Hydrochloride With Atezolizumab and/or Bevacizumab in Treating Patients With Recurrent Ovarian Fallopian Tube or Primary Peritoneal Cancer

This phase II/III trial studies how well pegylated liposomal doxorubicin hydrochloride with atezolizumab and/or bevacizumab work in treating patients with ovarian, fallopian tube, or primary peritoneal cancer that has come back (recurrent). Chemotherapy drugs, such as pegylated liposomal doxorubicin hydrochloride, work in different ways to stop the growth of tumor …

international normalized ratio
atezolizumab
warfarin
measurable disease
thromboplastin
Novant Health Oncology Specialists-Mount Airy
 (0.3 away) Contact site
  • 185 views
  • 04 Aug, 2021
  • +748 other locations
Testing The Addition of a New Anti-cancer Drug Venetoclax to the Usual Treatment (Ibrutinib and Obinutuzumab) in Untreated Older Patients With Chronic Lymphocytic Leukemia

This phase III trial compares adding a new anti-cancer drug (venetoclax) to the usual treatment (ibrutinib plus obinutuzumab) in older patients with chronic lymphocytic leukemia who have not received previous treatment. The addition of venetoclax to the usual treatment might prevent chronic lymphocytic leukemia from returning. This trial also will …

obinutuzumab
thrombocytopenia
platelet count
fatigue
chronic lymphocytic leukemia
Novant Health Oncology Specialists-Mount Airy
 (0.3 away) Contact site
  • 374 views
  • 04 Aug, 2021
  • +738 other locations