Mooresville, North Carolina Clinical Trials

A listing of Mooresville, North Carolina clinical trials actively recruiting patient volunteers.

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Found 10 clinical trials
Genetic Testing in Screening Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been or Will Be Removed by Surgery (The ALCHEMIST Screening Trial)

This ALCHEMIST trial studies genetic testing in screening patients with stage IB-IIIA non-small cell lung cancer that has been or will be removed by surgery. Studying the genes in a patient's tumor cells may help doctors select the best treatment for patients that have certain genetic changes.

squamous cell carcinoma
Lake Norman Hematology Oncology Specialists-Mooresville
 (2.6 away) Contact site
  • 04 Aug, 2021
  • +1138 other locations
Randomized Placebo-controlled Trial of FCM as Treatment for Heart Failure With Iron Deficiency

The primary objective of this study is to determine the efficacy and safety of iron therapy using intravenous (IV) ferric carboxymaltose (FCM), relative to placebo in the treatment of participants in heart failure with a reduced ejection fraction and with iron deficiency

ejection fraction
cardiac resynchronization therapy
b-type natriuretic peptide
Crossroads Clinical Research, Inc.
 (2.6 away) Contact site
  • 02 Aug, 2021
  • +365 other locations
A Study to Evaluate the Effect of Testosterone Replacement Therapy (TRT) on the Incidence of Major Adverse Cardiovascular Events (MACE) and Efficacy Measures in Hypogonadal Men

This is a blinded and placebo-controlled study of topical testosterone replacement therapy (TRT) in symptomatic hypogonadal men with increased risk for cardiovascular (CV) disease.

serum testosterone
testosterone topical
testosterone level
replacement therapy
Research Institute of the Caro /ID# 170341
 (2.6 away) Contact site
  • 30 Jul, 2021
  • +485 other locations
Efficacy and Safety of Benralizumab in Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD) With a History of Frequent Exacerbations

Phase 3 study to evaluate the efficacy and safety of a benralizumab in patients with moderate to very severe COPD with a history of frequent COPD exacerbations and elevated peripheral blood eosinophils (300/L). Eligible patients must have a history of 2 moderate and/or severe COPD exacerbations in the previous year …

severe chronic obstructive pulmonary disease
eosinophil count
Research Site
 (2.6 away) Contact site
  • 04 Aug, 2021
  • +426 other locations
Tezepelumab COPD Exacerbation Study

A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel Group, Phase 2a Study to Explore the Efficacy and Safety of Tezepelumab in Adults with Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD)

severe chronic obstructive pulmonary disease
copd exacerbation
ct scan
Research Site
 (2.6 away) Contact site
  • 23 Jul, 2021
  • +107 other locations
CompassHER2-pCR: Decreasing Chemotherapy for Breast Cancer Patients After Pre-surgery Chemo and Targeted Therapy

This trial studies how well paclitaxel, trastuzumab, and pertuzumab work in eliminating further chemotherapy after surgery in patients with HER2-positive stage II-IIIa breast cancer who have no cancer remaining at surgery (either in the breast or underarm lymph nodes) after pre-operative chemotherapy and HER2-targeted therapy. Drugs used in chemotherapy, such …

core needle biopsy
estrogen receptor
chemotherapy drugs
Novant Health Cancer Institute - Mooresville
 (3.2 away) Contact site
  • 01 Aug, 2021
  • +576 other locations
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

cardiovascular disease
body mass index
hemoglobin a1c
PMG Research Mooresville, LLC
 (3.2 away) Contact site
  • 29 Jul, 2021
  • +888 other locations
Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors Lymphomas or Multiple Myeloma (The MATCH Screening Trial)

This phase II MATCH trial studies how well treatment that is directed by genetic testing works in patients with solid tumors or lymphomas that have progressed following at least one line of standard treatment or for which no agreed upon treatment approach exists. Genetic tests look at the unique genetic …

liver metastasis
cancer treatment
platelet count
serum pregnancy test
Lake Norman Hematology Oncology Specialists-Mooresville
 (2.6 away) Contact site
  • 04 Aug, 2021
  • +1020 other locations
A Phase 3 Trial to Evaluate the Safety and Efficacy of Ensifentrine in Patients With COPD

The purpose of this study is to determine if ensifentrine is safe and effective for the treatment of patients with moderate to severe Chronic Obstructive Pulmonary Disease (COPD).

Clinical Research of Lake Norman
 (2.6 away) Contact site
  • 25 Jul, 2021
  • +110 other locations
Study Describing Cognitive Processing Speed Changes in Relapsing Multiple Sclerosis Subjects Treated With Ozanimod (RPC-1063)

This is a multicenter, longitudinal, single-arm, open-label study to describe the change from baseline in cognitive processing speed, measured by the SDMT, in subjects with RMS treated with ozanimod HCl 1 mg at 3 years. All subjects will receive orally administered ozanimod HCl 1 mg. The primary efficacy endpoint is …

relapsing multiple sclerosis
Lake Norman Neurology
 (2.6 away) Contact site
  • 21 Jul, 2021
  • +83 other locations